Difference between revisions of "Tumours of Haematopoietic and Lymphoid Tissues"

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== Myeloproliferative Neoplasms (MPN) ==
+
==Myeloproliferative Neoplasms (MPN) ([[HAEM4:Myeloproliferative Neoplasms (MPN)|Overview Page Link]])==
*[[Chronic Myeloid Leukemia (CML), BCR-ABL1 Positive]]
 
*[[Chronic Neutrophilic Leukemia (CNL)]]
 
*[[Polycythemia Vera (PV)]]
 
*[[Primary Myelofibrosis (PMF)]]
 
*[[Essential Thrombocythemia (ET)]]
 
*[[Chronic Eosinophilic Leukemia, Not Otherwise Specified]]
 
*[[Myeloproliferative Neoplasm (MPN), Unclassifiable]]
 
  
== Mastocytosis ==
+
*[[HAEM5:Chronic myeloid leukaemia]]
*[[Cutaneous Mastocytosis]]
+
*[[HAEM5:Chronic neutrophilic leukaemia]]
*[[Systemic Mastocytosis]]
+
*[[HAEM5:Polycythaemia vera]]
*[[Mast Cell Sarcoma]]
+
*[[HAEM5:Primary myelofibrosis]]
 +
*[[HAEM5:Essential thrombocythaemia]]
 +
*[[HAEM5:Chronic eosinophilic leukaemia]]
 +
*[[HAEM5:Myeloproliferative neoplasm, NOS]]
  
== Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2 ==
+
==Mastocytosis ([[HAEM4:Mastocytosis|Overview Page Link]])==
*[[Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement]]
 
*[[Myeloid/Lymphoid Neoplasms with PDGFRB Rearrangement]]
 
*[[Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement]]
 
*[[Myeloid/Lymphoid Neoplasms with PCM1-JAK2]]
 
  
== Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) ==
+
*[[HAEM5:Cutaneous mastocytosis]]
*[[Chronic Myelomonocytic Leukemia (CMML)]]
+
*[[HAEM5:Systemic mastocytosis]]
*[[Atypical Chronic Myeloid Leukemia (aCML), BCR-ABL1 Negative]]
+
*[[HAEM5:Mast cell sarcoma]]
*[[Juvenile Myelomonocytic Leukemia (JMML)]]
 
*[[Myelodysplastic/Myeloproliferative Neoplasms with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)|MDS/MPN with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)]]
 
*[[Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN), Unclassifiable|MDS/MPN, Unclassifiable]]
 
  
== Myelodysplastic Syndromes (MDS) ==
+
==Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2 ([[HAEM4:Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2|Overview Page Link]])==
*[[Myelodysplastic Syndrome (MDS) with Single Lineage Dysplasia|MDS with Single Lineage Dysplasia]]
 
*[[Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)|MDS with Ring Sideroblasts (MDS-RS)]]
 
*[[Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia|MDS with Ring Sideroblasts and Multilineage Dysplasia]]
 
*[[Myelodysplastic Syndrome (MDS) with Multilineage Dysplasia|MDS with Multilineage Dysplasia]]
 
*[[Myelodysplastic Syndrome (MDS) with Excess Blasts|MDS with Excess Blasts]]
 
*[[Myelodysplastic Syndrome (MDS) with Isolated del(5q)|MSD with Isolated del(5q)]]
 
*[[Myelodysplastic Syndrome (MDS), Unclassifiable|MDS, Unclassifiable]]
 
*[[Refractory Cytopenia of Childhood]]
 
  
== Myeloid Neoplasms with Germline Predisposition ==
+
*[[HAEM5:Myeloid/lymphoid neoplasm with PDGFRA rearrangement]]
 +
*[[HAEM5:Myeloid/lymphoid neoplasm with PDGFRB rearrangement]]
 +
*[[HAEM5:Myeloid/lymphoid neoplasm with FGFR1 rearrangement]]
 +
*[[HAEM5:Myeloid/lymphoid neoplasm with JAK2 rearrangement]]
  
*[[Acute Myeloid Leukaemia with Germline CEBPA Mutation]]
+
==Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) ([[HAEM4:Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)|Overview Page Link]])==
*[[Myeloid Neoplasms with Germline DDX41 Mutation]]
 
*[[Myeloid Neoplasms with Germline RUNX1 Mutation]]
 
*[[Myeloid Neoplasms with Germline ANKRD26 Mutation]]
 
*[[Myeloid Neoplasms with Germline ETV6 Mutation]]
 
*[[Myeloid Neoplasms with Germline GATA2 Mutation]]
 
  
== Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms ==
+
*[[HAEM5:Chronic myelomonocytic leukaemia]]
*[[Acute Myeloid Leukemia (AML) with Recurrent Genetic Abnormalities|AML with Recurrent Genetic Abnormalities]]
+
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm with neutrophilia]]
 +
*[[HAEM5:Juvenile myelomonocytic leukaemia]]
 +
*[[HAEM5:Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis|MDS/MPN with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)]]
 +
*[[HAEM4:Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN), Unclassifiable|MDS/MPN, Unclassifiable]]
  
  - [[Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22.1); RUNX1-RUNX1T1|AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1]]
+
==Myelodysplastic Syndromes (MDS) ([[HAEM4:Myelodysplastic Syndromes (MDS)|Overview Page Link]])==
  - [[Acute Myeloid Leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11|AML with with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11]]
 
  - [[Acute Promyelocytic Leukemia (APL) with PML-RARA]]
 
  - [[Acute Myeloid Leukemia (AML) with t(9;11)(p21.3;q23.3); KMT2A-MLLT3|AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3]]
 
  - [[Acute Myeloid Leukemia (AML) with t(6;9)(p23;q34.1); DEK-NUP214|AML with t(6;9)(p23;q34.1); DEK-NUP214]]
 
  - [[Acute Myeloid Leukemia (AML) with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM|AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM]]
 
  - [[Acute Myeloid Leukemia (AML) Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1|AML Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1]]
 
  - [[Acute Myeloid Leukemia (AML) with BCR-ABL1|AML with BCR-ABL1]]
 
  - [[Acute Myeloid Leukemia (AML) with Mutated NPM1|AML with Mutated NPM1]]
 
  - [[Acute Myeloid Leukemia (AML) with Biallelic Mutations of CEBPA|AML with Biallelic Mutations of CEBPA]]
 
  - [[Acute Myeloid Leukemia (AML) with Mutated RUNX1|AML with Mutated RUNX1]]
 
  
*[[Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes|AML with Myelodysplasia-Related Changes]]
+
*[[HAEM4:Myelodysplastic Syndrome (MDS) with Single Lineage Dysplasia|MDS with Single Lineage Dysplasia]]
 +
*[[HAEM4:Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)|MDS with Ring Sideroblasts (MDS-RS)]]
 +
*[[HAEM4:Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia|MDS with Ring Sideroblasts and Multilineage Dysplasia]]
 +
*[[HAEM4:Myelodysplastic Syndrome (MDS) with Multilineage Dysplasia|MDS with Multilineage Dysplasia]]
 +
*[[HAEM5:Myelodysplastic neoplasm with increased blasts|MDS with Excess Blasts]]
 +
*[[HAEM5:Myelodysplastic neoplasm with low blasts and 5q deletion|MDS with Isolated del(5q)]]
 +
*[[HAEM4:Myelodysplastic Syndrome (MDS), Unclassifiable|MDS, Unclassifiable]]
 +
*[[HAEM4:Refractory Cytopenia of Childhood]]
  
*[[Therapy-Related Myeloid Neoplasms]]
+
==Myeloid Neoplasms with Germline Predisposition ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
  
*[[Acute Myeloid Leukemia (AML), Not Otherwise Specified|AML, Not Otherwise Specified]]
+
*[[HAEM4:Acute Myeloid Leukaemia with Germline CEBPA Mutation]]
 +
*[[HAEM4:Myeloid Neoplasms with Germline DDX41 Mutation]]
 +
*[[HAEM4:Myeloid Neoplasms with Germline RUNX1 Mutation]]
 +
*[[HAEM4:Myeloid Neoplasms with Germline ANKRD26 Mutation]]
 +
*[[HAEM4:Myeloid Neoplasms with Germline ETV6 Mutation]]
 +
*[[HAEM4:Myeloid Neoplasms with Germline GATA2 Mutation]]
  
  - [[Acute Myeloid Leukemia (AML) with Minimal Differentiation|AML with Minimal Differentiation]]
+
==Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
  - [[Acute Myeloid Leukemia (AML) without Maturation|AML without Maturation]]
 
  - [[Acute Myeloid Leukemia (AML) with Maturation|AML with Maturation]]
 
  - [[Acute Myelomonocytic Leukemia]]
 
  - [[Acute Monoblastic and Monocytic Leukemia]]
 
  - [[Pure Erythroid Leukemia]]
 
  - [[Acute Megakaryoblastic Leukemia (AMKL)]]
 
  - [[Acute Basophilic Leukemia]]
 
  - [[Acute Panmyelosis with Myelofibrosis]]
 
  
*[[Myeloid Sarcoma]]
+
*[[HAEM4:Acute Myeloid Leukemia (AML) with Recurrent Genetic Abnormalities|AML with Recurrent Genetic Abnormalities]]
  
*[[Myeloid Proliferations Associated with Down Syndrome]]
+
  - [[HAEM5:Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion|AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1]]
 +
  - [[HAEM5:Acute myeloid leukaemia with CBFB::MYH11 fusion|AML with with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11]]
 +
  - [[HAEM5:Acute promyelocytic leukaemia with PML::RARA fusion]]
 +
  - [[HAEM5:Acute myeloid leukaemia with KMT2A rearrangement|AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3]]
 +
  - [[HAEM5:Acute myeloid leukaemia with DEK::NUP214 fusion|AML with t(6;9)(p23;q34.1); DEK-NUP214]]
 +
  - [[HAEM5:Acute myeloid leukaemia with MECOM rearrangement|AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM]]
 +
  - [[HAEM5:Acute myeloid leukaemia with RBM15::MRTFA fusion|AML Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1]]
 +
  - [[HAEM5:Acute myeloid leukaemia with BCR::ABL1 fusion|AML with BCR-ABL1]]
 +
  - [[HAEM5:Acute myeloid leukaemia with NPM1 mutation|AML with Mutated NPM1]]
 +
  - [[HAEM5:Acute myeloid leukaemia with CEBPA mutation|AML with Biallelic Mutations of CEBPA]]
 +
  - [[HAEM4:Acute Myeloid Leukemia (AML) with Mutated RUNX1|AML with Mutated RUNX1]]
  
  - [[Transient Abnormal Myelopoiesis (TAM) Associated with Down Syndrome]]
+
*[[HAEM5:Acute myeloid leukaemia, myelodysplasia-related|AML with Myelodysplasia-Related Changes]]
  - [[Myeloid Leukemia Associated with Down Syndrome]]
 
  
== Blastic Plasmacytoid Dendritic Cell Neoplasm ==
+
*[[HAEM5:Myeloid neoplasm post cytotoxic therapy]]
*[[Blastic Plasmacytoid Dendritic Cell Neoplasm]]
 
  
== Acute Leukemias of Ambiguous Lineage (MPAL) ==
+
*[[HAEM4:Acute Myeloid Leukemia (AML), Not Otherwise Specified|AML, Not Otherwise Specified]]
*[[Acute Leukemias of Ambiguous Lineage]]
 
  
   - [[Acute Undifferentiated Leukemia]]
+
   - [[HAEM5:Acute myeloid leukaemia with minimal differentiation|AML with Minimal Differentiation]]
   - [[Mixed Phenotype Acute Leukemia (MPAL) with t(9;22)(q34.1;q11.2); BCR-ABL1]]
+
   - [[HAEM5:Acute myeloid leukaemia without maturation|AML without Maturation]]
   - [[Mixed Phenotype Acute Leukemia (MPAL) with t(v;11q23.3); KMT2A Rearranged]]
+
  - [[HAEM5:Acute myeloid leukaemia with maturation|AML with Maturation]]
   - [[Mixed Phenotype Acute Leukemia (MPAL), B/Myeloid, Not Otherwise Specified]]
+
  - [[HAEM5:Acute myelomonocytic leukaemia]]
   - [[Mixed Phenotype Acute Leukemia (MPAL), T/Myeloid, Not Otherwise Specified]]
+
   - [[HAEM5:Acute monocytic leukaemia]]
   - [[Mixed-Phenotype Acute Leukemia, Not Otherwise Specified (NOS), Rare Types]]
+
   - [[HAEM5:Acute erythroid leukaemia]]
   - [[Acute Leukemias of Ambiguous Lineage, Not Otherwise Specified (NOS)]]
+
   - [[HAEM5:Acute megakaryoblastic leukaemia]]
 +
   - [[HAEM5:Acute basophilic leukaemia]]
 +
   - [[HAEM4:Acute Panmyelosis with Myelofibrosis]]
  
== Precursor Lymphoid Neoplasms (B-ALL, T-ALL) ==
+
*[[HAEM5:Myeloid sarcoma]]
*[[B-Lymphoblastic Leukemia/Lymphoma with Recurrent Genetic Abnormalities|B-Lymphoblastic Leukemia/Lymphoma (B-ALL) with Recurrent Genetic Abnormalities]]
 
  
  - [[B-Lymphoblastic Leukemia/Lymphoma with t(9;22)(q34.1;q11.2); BCR-ABL1|B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1]]
+
*[[HAEM4:Myeloid Proliferations Associated with Down Syndrome]]
  - [[B-Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A-Rearranged|B-ALL with t(v;11q23.3); KMT2A-Rearranged]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1|B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma with Hyperdiploidy|B-ALL with Hyperdiploidy]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma with Hypodiploidy|B-ALL with Hypodiploidy]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma with t(5;14)(q31.1;q32.1); IGH/IL3|B-ALL with t(5;14)(q31.1;q32.1); IGH/IL3]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma with t(1;19)(q23;p13.3); TCF3-PBX1|B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like|B-ALL, BCR-ABL1-Like]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma with iAMP21|B-ALL with iAMP21]]
 
  - [[B-Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified|B-ALL, Not Otherwise Specified]]
 
  
*[[T-Lymphoblastic Leukemia/Lymphoma|T-Lymphoblastic Leukemia/Lymphoma (T-ALL)]]
+
  - [[HAEM5:Myeloid proliferations associated with Down syndrome]]
 +
  - [[HAEM5:Myeloid proliferations associated with Down syndrome]]
  
  - [[Early T-Cell Precursor Lymphoblastic Leukemia]]
+
==Blastic Plasmacytoid Dendritic Cell Neoplasm ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
  - [[NK-Lymphoblastic Leukemia/Lymphoma]]
 
  
== Mature B-Cell Neoplasms (CLL, Plasma Cell Neoplasms, Non-Hodgkin Lymphomas) ==
+
*[[HAEM5:Blastic plasmacytoid dendritic cell neoplasm]]
*[[Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma]]
 
  - [[Monoclonal B-cell Lymphocytosis]]
 
  
*[[B-cell Prolymphocytic Leukemia]]
+
==Acute Leukemias of Ambiguous Lineage (MPAL) ([[HAEM4:Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms|Overview Page Link]])==
  
*[[Splenic Marginal Zone Lymphoma]]
+
*[[HAEM4:Acute Leukemias of Ambiguous Lineage]]
  
*[[Hairy Cell Leukemia]]
+
  - [[HAEM5:Acute undifferentiated leukaemia]]
 +
  - [[HAEM5:Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]]
 +
  - [[HAEM5:Mixed-phenotype acute leukaemia with KMT2A rearrangement]]
 +
  - [[HAEM5:Mixed-phenotype acute leukaemia, B/myeloid]]
 +
  - [[HAEM5:Mixed-phenotype acute leukaemia, T/myeloid]]
 +
  - [[HAEM5:Mixed-phenotype acute leukaemia, rare types]]
 +
  - [[HAEM4:Acute Leukemias of Ambiguous Lineage, Not Otherwise Specified (NOS)]]
  
*[[Splenic B-cell Lymphoma/Leukemia, Unclassifiable]]
+
==Precursor Lymphoid Neoplasms (B-ALL, T-ALL) ([[HAEM4:Precursor Lymphoid Neoplasms|Overview Page Link]])==
  - [[Splenic Diffuse Red Pulp Small B-cell Lymphoma]]
 
  - [[Hairy Cell Leukemia Variant]]
 
  
*[[Lymphoplasmacytic Lymphoma]]
+
*[[HAEM4:B-Lymphoblastic Leukemia/Lymphoma with Recurrent Genetic Abnormalities|B-Lymphoblastic Leukemia/Lymphoma (B-ALL) with Recurrent Genetic Abnormalities]]
  - [[Waldenstrom Macroglobulinemia]]
 
  
*[[IgM Monoclonal Gammopathy of Undetermined Significance]]
+
  - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion|B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1]]
 +
  - [[HAEM5:B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement|B-ALL with t(v;11q23.3); KMT2A-Rearranged]]
 +
  - [[HAEM5:B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion|B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1]]
 +
  - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy|B-ALL with Hyperdiploidy]]
 +
  - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with hypodiploidy|B-ALL with Hypodiploidy]]
 +
  - [[HAEM5:B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion|B-ALL with t(5;14)(q31.1;q32.1); IGH/IL3]]
 +
  - [[HAEM5:B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion|B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1]]
 +
  - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features|B-ALL, BCR-ABL1-Like]]
 +
  - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with iAMP21|B-ALL with iAMP21]]
 +
  - [[HAEM5:B-lymphoblastic leukaemia/lymphoma|B-ALL, Not Otherwise Specified]]
  
*[[Heavy Chain Diseases]]
+
*[[HAEM4:T-Lymphoblastic Leukemia/Lymphoma|T-Lymphoblastic Leukemia/Lymphoma (T-ALL)]]
  - [[Mu Heavy Chain Disease]]
 
  - [[Gamma Heavy Chain Disease]]
 
  - [[Alpha Heavy Chain Disease]]
 
  
*[[Plasma Cell Neoplasms]]
+
   - [[HAEM5:Early T-precursor lymphoblastic leukaemia / lymphoma]]
  - [[Non-IgM Monoclonal Gammopathy of Undetermined Significance]]
+
   - [[HAEM4:NK-Lymphoblastic Leukemia/Lymphoma]]
  - [[Plasma Cell Myeloma]]
 
  - [[Plasma Cell Myeloma Variants]]
 
  - [[Plasmacytoma]]
 
   - [[Monoclonal Immunoglobulin Deposition Diseases]]
 
        - [[Primary Amyloidosis]]
 
        - [[Light Chain and Heavy Chain Deposition Disease]]
 
   - [[Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
 
        - [[POEMS Syndrome]]
 
        - [[TEMPI Syndrome]]
 
  
*[[Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT Lymphoma)]]
+
==Mature B-Cell Neoplasms (CLL, Plasma Cell Neoplasms, Non-Hodgkin B-cell Lymphomas) ([[HAEM4:Mature B-Cell Neoplasms|Overview Page Link]])==
  
*[[Nodal Marginal Zone Lymphoma]]
+
*[[HAEM5:Chronic lymphocytic leukaemia/small lymphocytic lymphoma]]
  - [[Paediatric Nodal Marginal Zone Lymphoma]]
 
  
*[[Follicular Lymphoma]]
+
   - [[HAEM5:Monoclonal B-cell lymphocytosis]]
  - [[Testicular Follicular Lymphoma]]
 
  - [[In Situ Follicular Neoplasia]]
 
   - [[Duodenal-Type Follicular Lymphoma]]
 
  
*[[Paediatric-Type Follicular Lymphoma]]
+
*[[HAEM4:B-cell Prolymphocytic Leukemia]]
  
*[[Large B-cell Lymphoma with IRF4 Rearrangement]]
+
*[[HAEM5:Splenic marginal zone lymphoma]]
  
*[[Primary Cutaneous Follicle Centre Lymphoma]]
+
*[[HAEM5:Hairy cell leukaemia]]
  
*[[Mantle Cell Lymphoma]]
+
*[[HAEM4:Splenic B-cell Lymphoma/Leukemia, Unclassifiable]]
  - [[Leukemic Non-Nodal Mantle Cell Lymphoma]]
 
  - [[In Situ Mantle Cell Neoplasia]]
 
  
*[[Diffuse Large B-cell Lymphoma, Not Otherwise Specified]]
+
  - [[HAEM5:Splenic diffuse red pulp small B-cell lymphoma]]
 +
  - [[HAEM5:Hairy cell leukaemia Variant]]
  
*[[T-cell/Histiocyte-Rich Large B-cell Lymphoma]]
+
*[[HAEM5:Lymphoplasmacytic lymphoma]]
  
*[[Primary Diffuse Large B-cell Lymphoma of the CNS]]
+
  - [[HAEM5:Lymphoplasmacytic lymphoma]]
  
*[[Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type]]
+
*[[HAEM5:IgM monoclonal gammopathy of undetermined significance]]
  
*[[EBV-Positive Diffuse Large B-cell Lymphoma, Not Otherwise Specified (NOS)]]
+
*[[HAEM4:Heavy Chain Diseases]]
  
*[[EBV-Positive Mucocutaneous Ulcer]]
+
  - [[HAEM5:Mu heavy chain disease]]
 +
  - [[HAEM5:Gamma heavy chain disease]]
 +
  - [[HAEM5:Alpha heavy chain disease]]
  
*[[Diffuse Large B-cell Lymphoma Associated with Chronic Inflammation]]
+
*[[HAEM4:Plasma Cell Neoplasms]]
  - [[Fibrin-Associated Diffuse Large B-cell Lymphoma]]
 
  
*[[Lymphomatoid Granulomatosis]]
+
  - [[HAEM5:Non-IgM monoclonal gammopathy of undetermined significance]]
 +
  - [[HAEM5:Plasma cell myeloma / multiple myeloma]]
 +
  - [[HAEM5:Plasma cell myeloma / multiple myeloma Variants]]
 +
  - [[HAEM5:Plasmacytoma]]
 +
  - [[HAEM4:Monoclonal Immunoglobulin Deposition Diseases]]
 +
        - [[HAEM5:Immunoglobulin-related (AL) amyloidosis]]
 +
        - [[HAEM5:Monoclonal immunoglobulin deposition disease]]
 +
  - [[HAEM4:Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
 +
        - [[HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome]]
 +
        - [[HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome]]
  
*[[Primary Mediastinal (Thymic) Large B-cell Lymphoma]]
+
*[[HAEM5:Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue]]
  
*[[Intravascular Large B-cell Lymphoma]]
+
*[[HAEM5:Nodal marginal zone lymphoma]]
  
*[[ALK-Positive Large B-cell Lymphoma]]
+
  - [[HAEM5:Paediatric nodal marginal zone lymphoma]]
  
*[[Plasmablastic Lymphoma]]
+
*[[HAEM5:Follicular lymphoma]]
  
*[[Primary Effusion Lymphoma]]
+
  - [[HAEM5:Follicular lymphoma]]
 +
  - [[HAEM5:In situ follicular B-cell neoplasm]]
 +
  - [[HAEM5:Duodenal-type follicular lymphoma]]
  
*[[HHV8-Associated Lymphoproliferative Disorders]]
+
*[[HAEM5:Paediatric-type follicular lymphoma]]
  - [[Multicentric Castleman Disease]]
 
  - [[HHV8-Positive Diffuse Large B-cell Lymphoma, Not Otherwise Specified (NOS)]]
 
  - [[HHV8-Positive Germinotropic Lymphoproliferative Disorder]]
 
  
*[[Burkitt Lymphoma]]
+
*[[HAEM5:Large B-cell lymphoma with IRF4 rearrangement]]
  
*[[Burkitt-Like Lymphoma with 11q Aberration]]
+
*[[HAEM5:Primary cutaneous follicle centre lymphoma]]
  
*[[High-Grade B-cell Lymphoma]]
+
*[[HAEM5:Mantle cell lymphoma]]
  - [[High-Grade B-cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements]]
 
  - [[High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)]]
 
  
*[[B-cell Lymphoma, Unclassifiable, with Features Intermediate Between Diffuse Large B-cell Lymphoma and Classic Hodgkin Lymphoma]]
+
  - [[HAEM5:Leukaemic non-nodal mantle cell lymphoma]]
 +
  - [[HAEM5:In situ mantle cell neoplasm]]
  
== Mature T- and NK-cell Neoplasms ==
+
*[[HAEM4:Diffuse Large B-cell Lymphoma, Not Otherwise Specified]]
*[[T-cell Prolymphocytic Leukemia]]
 
  
*[[T-cell Large Granular Lymphocytic Leukemia]]
+
*[[HAEM5:T-cell/histiocyte-rich large B-cell lymphoma]]
  
*[[Chronic Lymphoproliferative Disorder of NK Cells]]
+
*[[HAEM5:Primary large B-cell lymphoma of immune-privileged sites]]
  
*[[Aggressive NK-cell Leukemia]]
+
*[[HAEM5:Primary cutaneous diffuse large B-cell lymphoma, leg type]]
  
*[[EBV-Positive T-cell and NK-cell Lymphoproliferative Diseases of Childhood]]
+
*[[HAEM5:EBV-positive diffuse large B-cell lymphoma]]
  - [[Systemic EBV-Positive T-cell Lymphoma of Childhood]]
 
  - [[Chronic Active EBV Infection of T- and NK-cell Type, Systemic Form]]
 
  - [[Hydroa Vacciniforme-Like Lymphoproliferative Disorder]]
 
  - [[Severe Mosquito Bite Allergy]]
 
  
*[[Adult T-cell Leukemia/Lymphoma]]
+
*[[HAEM5:EBV-positive mucocutaneous ulcer]]
  
*[[Extranodal NK/T-cell Lymphoma, Nasal Type]]
+
*[[HAEM5:Diffuse large B-cell lymphoma associated with chronic inflammation]]
  
*[[Intestinal T-cell Lymphoma]]
+
   - [[HAEM5:Fibrin-associated large B-cell lymphoma]]
  - [[Enteropathy-Associated T-cell Lymphoma]]
 
  - [[Monomorphic Epitheliotropic Intestinal T-cell Lymphoma]]
 
   - [[Intestinal T-cell Lymphoma, Not Otherwise Specified (NOS)]]
 
  - [[Indolent T-cell Lymphoproliferative Disorder of the Gastrointestinal Tract]]
 
  
*[[Hepatosplenic T-cell Lymphoma]]
+
*[[HAEM5:Lymphomatoid granulomatosis]]
  
*[[Subcutaneous Panniculitis-Like T-cell Lymphoma]]
+
*[[HAEM5:Primary mediastinal large B-cell lymphoma]]
  
*[[Mycosis Fungoides]]
+
*[[HAEM5:Intravascular large B-cell lymphoma]]
  
*[[Sézary Syndrome]]
+
*[[HAEM5:ALK-positive large B-cell lymphoma]]
  
*[[Primary Cutaneous CD30 Positive T-cell Lymphoproliferative Disorders]]
+
*[[HAEM5:Plasmablastic lymphoma]]
  - [[Lymphomatoid Papulosis]]
 
  - [[Primary Cutaneous Anaplastic Large Cell Lymphoma]]
 
  
*[[Primary Cutaneous Peripheral T-cell Lymphomas, Rare Subtypes]]
+
*[[HAEM5:Primary effusion lymphoma]]
  - [[Primary Cutaneous Gamma Delta T-cell Lymphoma]]
 
  - [[Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma]]
 
  - [[Primary Cutaneous Acral CD8+ T-cell Lymphoma]]
 
  - [[Primary Cutaneous CD4+ Small/Medium T-cell Lymphoproliferative Disorder]]
 
  
*[[Peripheral T-cell Lymphoma, Not Otherwise Specified (NOS)]]
+
*[[HAEM4:HHV8-Associated Lymphoproliferative Disorders]]
  
*[[Angioimmunoblastic T-cell Lymphoma and Other Nodal Lymphomas of T Follicular Helper Cell Origin]]
+
   - [[HAEM5:KSHV/HHV8-associated multicentric Castleman disease]]
   - [[Angioimmunoblastic T-cell Lymphoma]]
+
   - [[HAEM5:KSHV/HHV8-positive diffuse large B-cell lymphoma]]
   - [[Follicular T-cell Lymphoma]]
+
   - [[HAEM5:KSHV/HHV8-positive germinotropic lymphoproliferative disorder]]
   - [[Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype]]
 
  
*[[Anaplastic Large Cell Lymphoma, ALK-Positive]]
+
*[[HAEM5:Burkitt lymphoma]]
  
*[[Anaplastic Large Cell Lymphoma, ALK-Negative]]
+
*[[HAEM5:High grade B-cell lymphoma with 11q aberrations]]
  
*[[Breast Implant-Associated Anaplastic Large Cell Lymphoma]]
+
*[[HAEM4:High-Grade B-cell Lymphoma]]
  
== Hodgkin Lymphomas==
+
  - [[HAEM4:High-Grade B-cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements]]
*[[Nodular Lymphocyte Predominant Hodgkin Lymphoma]]
+
  - [[HAEM4:High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)]]
  
*[[Classic Hodgkin Lymphoma]]
+
*[[HAEM5:Mediastinal grey zone lymphoma]]
  - [[Nodular Sclerosis Classic Hodgkin Lymphoma]]
 
  - [[Lymphocyte-Rich Classic Hodgkin Lymphoma]]
 
  - [[Mixed Cellularity Classic Hodgkin Lymphoma]]
 
  - [[Lymphocyte-Depleted Classic Hodgkin Lymphoma]]
 
  
== Immunodeficiency-Associated Lymphoproliferative Disorders==
+
==Mature T- and NK-cell Neoplasms ([[HAEM4:Mature T- and NK-cell Neoplasms|Overview Page Link]])==
*[[Lymphomas Associated with HIV Infection]]
 
  
*[[Post-Transplant Lymphoproliferative Disorders]]
+
*[[HAEM5:T-prolymphocytic leukaemia]]
  - [[Non-Destructive Post-Transplant Lymphoproliferative Disorders]]
 
  - [[Polymorphic Post-Transplant Lymphoproliferative Disorders]]
 
  - [[Monomorphic Post-Transplant Lymphoproliferative Disorders (B- and T/NK-cell Types)]]
 
        - [[Monomorphic B-cell PTLD]]
 
        - [[Monomorphic T/NK-cell PTLD]]
 
  - [[Classical Hodgkin Lymphoma Post-Transplant Lymphoproliferative Disorder]]
 
  
*[[Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders]]
+
*[[HAEM5:T-large granular lymphocytic leukaemia]]
  
== Histiocytic and Dendritic Cell Neoplasms ==
+
*[[HAEM5:NK-large granular lymphocytic leukaemia]]
*[[Histiocytic Sarcoma]]
 
  
*[[Tumors Derived From Langerhans Cells]]
+
*[[HAEM5:Aggressive NK-cell leukaemia]]
  - [[Langerhans Cell Histiocytosis]]
 
  - [[Langerhans Cell Sarcoma]]
 
  
*[[Indeterminate Dendritic Cell Tumour]]
+
*[[HAEM4:EBV-Positive T-cell and NK-cell Lymphoproliferative Diseases of Childhood]]
  
*[[Interdigitating Dendritic Cell Sarcoma]]
+
  - [[HAEM5:Systemic EBV-positive T-cell lymphoma of childhood]]
 +
  - [[HAEM5:Systemic chronic active EBV disease]]
 +
  - [[HAEM5:Hydroa vacciniforme lymphoproliferative disorder]]
 +
  - [[HAEM5:Severe mosquito bite allergy]]
  
*[[Follicular Dendritic Cell Sarcoma]]
+
*[[HAEM5:Adult T-cell leukaemia/lymphoma]]
  - [[Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma]]
 
  
*[[Fibroblastic Reticular Cell Tumor]]
+
*[[HAEM5:Extranodal NK/T-cell lymphoma]]
  
*[[Disseminated Juvenile Xanthogranuloma]]
+
*[[HAEM4:Intestinal T-cell Lymphoma]]
  
*[[Erdheim-Chester Disease]]
+
  - [[HAEM5:Enteropathy-associated T-cell lymphoma]]
 +
  - [[HAEM5:Monomorphic epitheliotropic intestinal T-cell lymphoma]]
 +
  - [[HAEM4:Intestinal T-cell Lymphoma, Not Otherwise Specified (NOS)]]
 +
  - [[HAEM5:Indolent T-cell lymphoma of the gastrointestinal tract]]
 +
 
 +
*[[HAEM5:Hepatosplenic T-cell lymphoma]]
 +
 
 +
*[[HAEM5:Subcutaneous panniculitis-like T-cell lymphoma]]
 +
 
 +
*[[HAEM5:Mycosis fungoides]]
 +
 
 +
*[[HAEM5:Sezary syndrome]]
 +
 
 +
*[[HAEM4:Primary Cutaneous CD30 Positive T-cell Lymphoproliferative Disorders]]
 +
 
 +
  - [[HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis]]
 +
  - [[HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma]]
 +
 
 +
*[[HAEM4:Primary Cutaneous Peripheral T-cell Lymphomas, Rare Subtypes]]
 +
 
 +
  - [[HAEM5:Primary cutaneous gamma/delta T-cell lymphoma]]
 +
  - [[HAEM5:Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma]]
 +
  - [[HAEM5:Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder]]
 +
  - [[HAEM5:Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder]]
 +
 
 +
*[[HAEM5:Peripheral T-cell lymphoma, NOS]]
 +
 
 +
*[[HAEM4:Angioimmunoblastic T-cell Lymphoma and Other Nodal Lymphomas of T Follicular Helper Cell Origin]]
 +
 
 +
  - [[HAEM5:Nodal TFH cell lymphoma, angioimmunoblastic-type]]
 +
  - [[HAEM5:Nodal TFH cell lymphoma, follicular-type]]
 +
  - [[HAEM5:Nodal TFH cell lymphoma, NOS]]
 +
 
 +
*[[HAEM5:ALK-positive anaplastic large cell lymphoma]]
 +
 
 +
*[[HAEM5:ALK-negative anaplastic large cell lymphoma]]
 +
 
 +
*[[HAEM5:Breast implant-associated anaplastic large cell lymphoma]]
 +
 
 +
==Hodgkin Lymphomas ([[HAEM4:Hodgkin Lymphomas|Overview Page Link]])==
 +
 
 +
*[[HAEM5:Nodular lymphocyte predominant Hodgkin lymphoma]]
 +
 
 +
*[[HAEM4:Classic Hodgkin Lymphoma]]
 +
 
 +
  - [[HAEM5:Classic Hodgkin lymphoma]]
 +
  - [[HAEM5:Classic Hodgkin lymphoma]]
 +
  - [[HAEM5:Classic Hodgkin lymphoma]]
 +
  - [[HAEM5:Classic Hodgkin lymphoma]]
 +
 
 +
==Immunodeficiency-Associated Lymphoproliferative Disorders ([[HAEM4:Immunodeficiency-Associated Lymphoproliferative Disorders|Overview Page Link]])==
 +
 
 +
*[[HAEM4:Lymphomas Associated with HIV Infection]]
 +
 
 +
*[[HAEM4:Post-Transplant Lymphoproliferative Disorders]]
 +
 
 +
  - [[HAEM4:Non-Destructive Post-Transplant Lymphoproliferative Disorders]]
 +
  - [[HAEM5:Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation]]
 +
  - [[HAEM4:Monomorphic Post-Transplant Lymphoproliferative Disorders (B- and T/NK-cell Types)]]
 +
        - [[HAEM4:Monomorphic B-cell PTLD]]
 +
        - [[HAEM4:Monomorphic T/NK-cell PTLD]]
 +
  - [[HAEM4:Classical Hodgkin Lymphoma Post-Transplant Lymphoproliferative Disorder]]
 +
 
 +
*[[HAEM4:Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders]]
 +
 
 +
==Histiocytic and Dendritic Cell Neoplasms ([[HAEM4:Histiocytic and Dendritic Cell Neoplasms|Overview Page Link]])==
 +
 
 +
*[[HAEM5:Histiocytic sarcoma]]
 +
 
 +
*[[HAEM4:Tumors Derived From Langerhans Cells]]
 +
 
 +
  - [[HAEM5:Langerhans cell histiocytosis]]
 +
  - [[HAEM5:Langerhans cell sarcoma]]
 +
 
 +
*[[HAEM5:Indeterminate dendritic cell tumour]]
 +
 
 +
*[[HAEM5:Interdigitating dendritic cell sarcoma]]
 +
 
 +
*[[HAEM5:Follicular dendritic cell sarcoma]]
 +
 
 +
  - [[HAEM5:EBV-positive inflammatory follicular dendritic cell sarcoma]]
 +
 
 +
*[[HAEM5:Fibroblastic reticular cell tumour]]
 +
 
 +
*[[HAEM5:Juvenile xanthogranuloma]]
 +
 
 +
*[[HAEM5:Erdheim-Chester disease]]
 +
 
 +
==Notes==
 +
<nowiki>*</nowiki>The hierarchical tumour classification structure displayed on this page is reproduced from the [https://tumourclassification.iarc.who.int/welcome/ WHO Classification of Tumours] with permission from the copyright holder, ©International Agency for Research on Cancer.

Latest revision as of 15:14, 12 December 2023

Myeloproliferative Neoplasms (MPN) (Overview Page Link)

Mastocytosis (Overview Page Link)

Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB or FGFR1, or with PCM1-JAK2 (Overview Page Link)

Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) (Overview Page Link)

Myelodysplastic Syndromes (MDS) (Overview Page Link)

Myeloid Neoplasms with Germline Predisposition (Overview Page Link)

Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms (Overview Page Link)

  - AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1
  - AML with with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11
  - HAEM5:Acute promyelocytic leukaemia with PML::RARA fusion
  - AML with t(9;11)(p21.3;q23.3); KMT2A-MLLT3
  - AML with t(6;9)(p23;q34.1); DEK-NUP214
  - AML with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM
  - AML Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1
  - AML with BCR-ABL1
  - AML with Mutated NPM1
  - AML with Biallelic Mutations of CEBPA
  - AML with Mutated RUNX1
  - AML with Minimal Differentiation
  - AML without Maturation
  - AML with Maturation
  - HAEM5:Acute myelomonocytic leukaemia
  - HAEM5:Acute monocytic leukaemia
  - HAEM5:Acute erythroid leukaemia
  - HAEM5:Acute megakaryoblastic leukaemia
  - HAEM5:Acute basophilic leukaemia
  - HAEM4:Acute Panmyelosis with Myelofibrosis
  - HAEM5:Myeloid proliferations associated with Down syndrome
  - HAEM5:Myeloid proliferations associated with Down syndrome

Blastic Plasmacytoid Dendritic Cell Neoplasm (Overview Page Link)

Acute Leukemias of Ambiguous Lineage (MPAL) (Overview Page Link)

  - HAEM5:Acute undifferentiated leukaemia
  - HAEM5:Mixed-phenotype acute leukaemia with BCR::ABL1 fusion
  - HAEM5:Mixed-phenotype acute leukaemia with KMT2A rearrangement
  - HAEM5:Mixed-phenotype acute leukaemia, B/myeloid
  - HAEM5:Mixed-phenotype acute leukaemia, T/myeloid
  - HAEM5:Mixed-phenotype acute leukaemia, rare types
  - HAEM4:Acute Leukemias of Ambiguous Lineage, Not Otherwise Specified (NOS)

Precursor Lymphoid Neoplasms (B-ALL, T-ALL) (Overview Page Link)

  - B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1
  - B-ALL with t(v;11q23.3); KMT2A-Rearranged
  - B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1
  - B-ALL with Hyperdiploidy
  - B-ALL with Hypodiploidy
  - B-ALL with t(5;14)(q31.1;q32.1); IGH/IL3
  - B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1
  - B-ALL, BCR-ABL1-Like
  - B-ALL with iAMP21
  - B-ALL, Not Otherwise Specified
  - HAEM5:Early T-precursor lymphoblastic leukaemia / lymphoma
  - HAEM4:NK-Lymphoblastic Leukemia/Lymphoma

Mature B-Cell Neoplasms (CLL, Plasma Cell Neoplasms, Non-Hodgkin B-cell Lymphomas) (Overview Page Link)

  - HAEM5:Monoclonal B-cell lymphocytosis
  - HAEM5:Splenic diffuse red pulp small B-cell lymphoma
  - HAEM5:Hairy cell leukaemia Variant
  - HAEM5:Lymphoplasmacytic lymphoma
  - HAEM5:Mu heavy chain disease
  - HAEM5:Gamma heavy chain disease
  - HAEM5:Alpha heavy chain disease
  - HAEM5:Non-IgM monoclonal gammopathy of undetermined significance
  - HAEM5:Plasma cell myeloma / multiple myeloma
  - HAEM5:Plasma cell myeloma / multiple myeloma Variants
  - HAEM5:Plasmacytoma
  - HAEM4:Monoclonal Immunoglobulin Deposition Diseases
        - HAEM5:Immunoglobulin-related (AL) amyloidosis
        - HAEM5:Monoclonal immunoglobulin deposition disease
  - HAEM4:Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome
        - HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome
        - HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome
  - HAEM5:Paediatric nodal marginal zone lymphoma
  - HAEM5:Follicular lymphoma
  - HAEM5:In situ follicular B-cell neoplasm
  - HAEM5:Duodenal-type follicular lymphoma
  - HAEM5:Leukaemic non-nodal mantle cell lymphoma
  - HAEM5:In situ mantle cell neoplasm
  - HAEM5:Fibrin-associated large B-cell lymphoma
  - HAEM5:KSHV/HHV8-associated multicentric Castleman disease
  - HAEM5:KSHV/HHV8-positive diffuse large B-cell lymphoma
  - HAEM5:KSHV/HHV8-positive germinotropic lymphoproliferative disorder
  - HAEM4:High-Grade B-cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements
  - HAEM4:High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)

Mature T- and NK-cell Neoplasms (Overview Page Link)

  - HAEM5:Systemic EBV-positive T-cell lymphoma of childhood
  - HAEM5:Systemic chronic active EBV disease
  - HAEM5:Hydroa vacciniforme lymphoproliferative disorder
  - HAEM5:Severe mosquito bite allergy
  - HAEM5:Enteropathy-associated T-cell lymphoma
  - HAEM5:Monomorphic epitheliotropic intestinal T-cell lymphoma
  - HAEM4:Intestinal T-cell Lymphoma, Not Otherwise Specified (NOS)
  - HAEM5:Indolent T-cell lymphoma of the gastrointestinal tract
  - HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis
  - HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma
  - HAEM5:Primary cutaneous gamma/delta T-cell lymphoma
  - HAEM5:Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma
  - HAEM5:Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder
  - HAEM5:Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder
  - HAEM5:Nodal TFH cell lymphoma, angioimmunoblastic-type
  - HAEM5:Nodal TFH cell lymphoma, follicular-type
  - HAEM5:Nodal TFH cell lymphoma, NOS

Hodgkin Lymphomas (Overview Page Link)

  - HAEM5:Classic Hodgkin lymphoma
  - HAEM5:Classic Hodgkin lymphoma
  - HAEM5:Classic Hodgkin lymphoma
  - HAEM5:Classic Hodgkin lymphoma

Immunodeficiency-Associated Lymphoproliferative Disorders (Overview Page Link)

  - HAEM4:Non-Destructive Post-Transplant Lymphoproliferative Disorders
  - HAEM5:Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation
  - HAEM4:Monomorphic Post-Transplant Lymphoproliferative Disorders (B- and T/NK-cell Types)
        - HAEM4:Monomorphic B-cell PTLD
        - HAEM4:Monomorphic T/NK-cell PTLD
  - HAEM4:Classical Hodgkin Lymphoma Post-Transplant Lymphoproliferative Disorder

Histiocytic and Dendritic Cell Neoplasms (Overview Page Link)

  - HAEM5:Langerhans cell histiocytosis
  - HAEM5:Langerhans cell sarcoma
  - HAEM5:EBV-positive inflammatory follicular dendritic cell sarcoma

Notes

*The hierarchical tumour classification structure displayed on this page is reproduced from the WHO Classification of Tumours with permission from the copyright holder, ©International Agency for Research on Cancer.