Herein are defined the founding principles of the Compendium of Cancer Genome Aberrations (CCGA), which are based on CCGA development through interdisciplinary and community consensus efforts for use as a freely accessible resource. These founding principles are supported by CCGA leadership (Editor-in-Chief and CCGA steering committee) and CCGA Workgroup members, and approved by the Cancer Genomic Consortium Board of Directors (CGC BOD).
- Democratization of Genomic Knowledge: The CGC and CCGA are dedicated to offering genomic resources to the community. The CCGA is currently and will remain an open-access (i.e. free and public) resource.
- Inclusivity and Diversity: The CCGA and CGC actively promote diversity and inclusivity of contributors with various backgrounds, institutions, nationalities and experience levels in the field who have applicable knowledge and/or expertise. Contributors and users of the CCGA are encouraged, but not required, to be CGC members.
- Community Collaborations: The CCGA brings together cancer genetics and genomics knowledge through curation and connections to existing resources. The CCGA and CGC form strategic partnerships with other organizations and project leaders who have similar core principles and complementary goals.
- Learning and Teaching: The CCGA is an educational resource. Information in the CCGA is freely available for educational purposes. Trainees are also encouraged to contribute to the creation and maintenance of CCGA content with guidance and support from mentors.
The CCGA is a global collaborative effort to describe clinical context-based knowledge for gene- and chromosome-level abnormalities observed in cancer.
- Provide a centralized resource of genetic correlates for pathologic entities, structured based on current disease-level WHO classification system, with direct links to significant internal and external site content.
- Support real-time updating and sharing of clinically relevant content that is peer-reviewed and easily searchable.
- Engage community experts and their trainees in curating, updating and utilizing content.
- Include cancer variant knowledge identified through diverse methods and across multiple disciplines.
- Facilitate building educational content that describes the latest advancements in the field.
The global hub for clinical cancer genomic aberrations.
The CCGA is a Cancer Genomics Consortium (CGC)-supported resource.