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− | + | {{DISPLAYTITLE:Haematolymphoid Tumours 5th ed. (HAEM5) Table of Contents}} | |
+ | |||
+ | ==Myeloid proliferations and neoplasms== | ||
+ | |||
+ | '''Myeloid precursor lesions''' | ||
+ | ''Clonal Haematopoiesis'' | ||
+ | - [[HAEM5:Clonal haematopoiesis]] | ||
+ | - [[HAEM5:Clonal cytopenias of undetermined significance]] | ||
+ | |||
+ | '''Myeloproliferative neoplasms | ||
+ | ''Myeloproliferative neoplasms'' | ||
+ | - [[HAEM5:Chronic myeloid leukaemia]] | ||
+ | - [[HAEM5:Chronic neutrophilic leukaemia]] | ||
+ | - [[HAEM5:Chronic eosinophilic leukaemia]] | ||
+ | - [[HAEM5:Polycythaemia vera]] | ||
+ | - [[HAEM5:Essential thrombocythaemia]] | ||
+ | - [[HAEM5:Primary myelofibrosis]] | ||
+ | - [[HAEM5:Juvenile myelomonocytic leukaemia]] | ||
+ | - [[HAEM5:Myeloproliferative neoplasm, NOS]] | ||
+ | |||
+ | '''Mastocytosis''' | ||
+ | - [[HAEM5:Cutaneous mastocytosis]] | ||
+ | - [[HAEM5:Systemic mastocytosis]] | ||
+ | - [[HAEM5:Mast cell sarcoma]] | ||
+ | |||
+ | '''Myelodysplastic neoplasms''' | ||
+ | ''Myelodysplastic neoplasms, with defining genetic abnormalities'' | ||
+ | - [[HAEM5:Myelodysplastic neoplasm with low blasts and 5q deletion]] | ||
+ | - [[HAEM5:Myelodysplastic neoplasm with low blasts and SF3B1 mutation]] | ||
+ | - [[HAEM5:Myelodysplastic neoplasm with biallelic TP53 inactivation]] | ||
+ | ''Myelodysplastic neoplasms, morphologically defined'' | ||
+ | - [[HAEM5:Myelodysplastic neoplasm with low blasts]] | ||
+ | - [[HAEM5:Myelodysplastic neoplasm, hypoplastic]] | ||
+ | - [[HAEM5:Myelodysplastic neoplasm with increased blasts]] | ||
+ | ''Myelodysplastic neoplasms of childhood'' | ||
+ | - [[HAEM5:Childhood myelodysplastic neoplasm with low blasts]] | ||
+ | - [[HAEM5:Childhood myelodysplastic neoplasm with increased blasts]] | ||
+ | |||
+ | '''Myelodysplastic/myeloproliferative neoplasms''' | ||
+ | - [[HAEM5:Chronic myelomonocytic leukaemia]] | ||
+ | - [[HAEM5:Myelodysplastic/myeloproliferative neoplasm with neutrophilia]] | ||
+ | - [[HAEM5:Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis]] | ||
+ | - [[HAEM5:Myelodysplastic/myeloproliferative neoplasm, NOS]] | ||
+ | |||
+ | '''Acute myeloid leukaemia''' | ||
+ | ''Acute myeloid leukaemia with defining genetic abnormalities'' | ||
+ | - [[HAEM5:Acute promyelocytic leukaemia with PML::RARA fusion]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with CBFB::MYH11 fusion]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with DEK::NUP214 fusion]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with RBM15::MRTFA fusion]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with BCR::ABL1 fusion]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with KMT2A rearrangement]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with MECOM rearrangement]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with NUP98 rearrangement]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with NPM1 mutation]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with CEBPA mutation]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia, myelodysplasia-related]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with other defined genetic alterations]] | ||
+ | ''Acute myeloid leukaemia, defined by differentiation'' | ||
+ | - [[HAEM5:Acute myeloid leukaemia with minimal differentiation]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia without maturation]] | ||
+ | - [[HAEM5:Acute myeloid leukaemia with maturation]] | ||
+ | - [[HAEM5:Acute basophilic leukaemia]] | ||
+ | - [[HAEM5:Acute myelomonocytic leukaemia]] | ||
+ | - [[HAEM5:Acute monocytic leukaemia]] | ||
+ | - [[HAEM5:Acute erythroid leukaemia]] | ||
+ | - [[HAEM5:Acute megakaryoblastic leukaemia]] | ||
+ | ''Myeloid sarcoma'' | ||
+ | - [[HAEM5:Myeloid sarcoma]] | ||
+ | |||
+ | '''Myeloid neoplasms, secondary''' | ||
+ | ''Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions'' | ||
+ | - [[HAEM5:Myeloid neoplasm post cytotoxic therapy]] | ||
+ | - [[HAEM5:Myeloid neoplasms associated with germline predisposition]] | ||
+ | - [[HAEM5:Myeloid proliferations associated with Down syndrome]] | ||
+ | |||
+ | '''Myeloid/lymphoid neoplasms''' | ||
+ | ''Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement'' | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasm with PDGFRA rearrangement]] | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasm with PDGFRB rearrangement]] | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasm with FGFR1 rearrangement]] | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasm with JAK2 rearrangement]] | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasm with FLT3 rearrangement]] | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion]] | ||
+ | - [[HAEM5:Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes]] | ||
+ | |||
+ | '''Acute leukaemias of mixed or ambiguous lineage''' | ||
+ | ''Acute leukaemia of ambiguous lineage with defining genetic abnormalities'' | ||
+ | - [[HAEM5:Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]] | ||
+ | - [[HAEM5:Mixed-phenotype acute leukaemia with KMT2A rearrangement]] | ||
+ | - [[HAEM5:Acute leukaemia of ambiguous lineage with other defined genetic alterations ]] | ||
+ | ''Acute leukaemia of ambiguous lineage, immunophenotypically defined'' | ||
+ | - [[HAEM5:Mixed-phenotype acute leukaemia, B/myeloid]] | ||
+ | - [[HAEM5:Mixed-phenotype acute leukaemia, T/myeloid]] | ||
+ | - [[HAEM5:Mixed-phenotype acute leukaemia, rare types]] | ||
+ | - [[HAEM5:Acute leukaemia of ambiguous lineage, NOS]] | ||
+ | - [[HAEM5:Acute undifferentiated leukaemia]] | ||
+ | ==Histiocytic/Dendritic cell neoplasms== | ||
+ | |||
+ | '''Plasmacytoid dendritic cell neoplasms''' | ||
+ | ''Plasmacytoid dendritic cell neoplasms'' | ||
+ | - [[HAEM5:Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm]] | ||
+ | - [[HAEM5:Blastic plasmacytoid dendritic cell neoplasm]] | ||
+ | |||
+ | '''Langerhans cell and other dendritic cell neoplasms''' | ||
+ | ''Langerhans cells neoplasms'' | ||
+ | - [[HAEM5:Langerhans cell histiocytosis]] | ||
+ | - [[HAEM5:Langerhans cell sarcoma]] | ||
+ | ''Other dendritic cell neoplasms'' | ||
+ | - [[HAEM5:Indeterminate dendritic cell tumour]] | ||
+ | - [[HAEM5:Interdigitating dendritic cell sarcoma]] | ||
+ | |||
+ | '''Histiocyte/macrophage neoplasms''' | ||
+ | ''Histiocytic neoplasms'' | ||
+ | - [[HAEM5:Juvenile xanthogranuloma]] | ||
+ | - [[HAEM5:Erdheim-Chester disease]] | ||
+ | - [[HAEM5:Rosai-Dorfman Disease]] | ||
+ | - [[HAEM5:ALK-positive histiocytosis]] | ||
+ | - [[HAEM5:Histiocytic sarcoma]] | ||
+ | ==B-cell lymphoid proliferations and lymphomas== | ||
+ | |||
+ | '''Tumour like lesions with B-cell predominance''' | ||
+ | - [[HAEM5:Reactive B-cell rich lymphoid proliferations that can mimic lymphoma]] | ||
+ | - [[HAEM5:IgG4-related disease]] | ||
+ | - [[HAEM5:Unicentric Castleman disease]] | ||
+ | - [[HAEM5:Idiopathic multicentric Castleman disease]] | ||
+ | - [[HAEM5:KSHV/HHV8-associated multicentric Castleman disease]] | ||
+ | |||
+ | '''Precursor B-cell neoplasms''' | ||
+ | ''B-lymphoblastic leukaemias/lymphomas'' | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with hypodiploidy]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with iAMP21]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features]] | ||
+ | - [[HAEM5:B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement]] | ||
+ | - [[HAEM5:B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features]] | ||
+ | - [[HAEM5:B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion]] | ||
+ | - [[HAEM5:B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion ]] | ||
+ | - [[HAEM5:B lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations]] | ||
+ | - [[HAEM5:B-lymphoblastic leukaemia/lymphoma, NOS]] | ||
+ | |||
+ | '''Mature B-cell neoplasms''' | ||
+ | ''Pre-neoplastic and neoplastic small lymphocytic proliferations '' | ||
+ | - [[HAEM5:Monoclonal B-cell lymphocytosis]] | ||
+ | - [[HAEM5:Chronic lymphocytic leukaemia/small lymphocytic lymphoma]] | ||
+ | ''Splenic B-cell lymphomas and leukaemias'' | ||
+ | - [[HAEM5:Hairy cell leukaemia]] | ||
+ | - [[HAEM5:Splenic marginal zone lymphoma]] | ||
+ | - [[HAEM5:Splenic diffuse red pulp small B-cell lymphoma]] | ||
+ | - [[HAEM5:Splenic B-cell lymphoma/leukaemia with prominent nucleoli]] | ||
+ | ''Lymphoplasmacytic lymphoma'' | ||
+ | - [[HAEM5:Lymphoplasmacytic lymphoma]] | ||
+ | ''Marginal zone lymphoma'' | ||
+ | - [[HAEM5:Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue]] | ||
+ | - [[HAEM5:Primary cutaneous marginal zone lymphoma ]] | ||
+ | - [[HAEM5:Nodal marginal zone lymphoma]] | ||
+ | - [[HAEM5:Paediatric nodal marginal zone lymphoma]] | ||
+ | ''Follicular lymphoma'' | ||
+ | - [[HAEM5:In situ follicular B-cell neoplasm]] | ||
+ | - [[HAEM5:Follicular lymphoma]] | ||
+ | - [[HAEM5:Paediatric-type follicular lymphoma]] | ||
+ | - [[HAEM5:Duodenal-type follicular lymphoma]] | ||
+ | ''Cutaneous follicle centre lymphoma'' | ||
+ | - [[HAEM5:Primary cutaneous follicle centre lymphoma]] | ||
+ | ''Mantle cell lymphoma'' | ||
+ | - [[HAEM5:In situ mantle cell neoplasm]] | ||
+ | - [[HAEM5:Mantle cell lymphoma]] | ||
+ | - [[HAEM5:Leukaemic non-nodal mantle cell lymphoma]] | ||
+ | ''Transformations of indolent B-cell lymphomas'' | ||
+ | - [[HAEM5:Transformations of indolent B-cell lymphomas]] | ||
+ | ''Large B-cell lymphomas'' | ||
+ | - [[HAEM5:Diffuse large B-cell lymphoma, NOS]] | ||
+ | - [[HAEM5:T-cell/histiocyte-rich large B-cell lymphoma]] | ||
+ | - [[HAEM5:Diffuse large B-cell lymphoma / high grade B-cell lymphoma with MYC and BCL2 rearrangements]] | ||
+ | - [[HAEM5:ALK-positive large B-cell lymphoma]] | ||
+ | - [[HAEM5:Large B-cell lymphoma with IRF4 rearrangement]] | ||
+ | - [[HAEM5:High grade B-cell lymphoma with 11q aberrations]] | ||
+ | - [[HAEM5:Lymphomatoid granulomatosis]] | ||
+ | - [[HAEM5:EBV-positive diffuse large B-cell lymphoma]] | ||
+ | - [[HAEM5:Diffuse large B-cell lymphoma associated with chronic inflammation]] | ||
+ | - [[HAEM5:Fibrin-associated large B-cell lymphoma]] | ||
+ | - [[HAEM5:Fluid overload-associated large B-cell lymphoma]] | ||
+ | - [[HAEM5:Plasmablastic lymphoma]] | ||
+ | - [[HAEM5:Primary large B-cell lymphoma of immune-privileged sites]] | ||
+ | - [[HAEM5:Primary cutaneous diffuse large B-cell lymphoma, leg type]] | ||
+ | - [[HAEM5:Intravascular large B-cell lymphoma]] | ||
+ | - [[HAEM5:Primary mediastinal large B-cell lymphoma]] | ||
+ | - [[HAEM5:Mediastinal grey zone lymphoma]] | ||
+ | - [[HAEM5:High-grade B-cell lymphoma, NOS]] | ||
+ | ''Burkitt lymphoma'' | ||
+ | - [[HAEM5:Burkitt lymphoma]] | ||
+ | ''KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas'' | ||
+ | - [[HAEM5:Primary effusion lymphoma]] | ||
+ | - [[HAEM5:KSHV/HHV8-positive diffuse large B-cell lymphoma]] | ||
+ | - [[HAEM5:KSHV/HHV8-positive germinotropic lymphoproliferative disorder]] | ||
+ | ''Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation'' | ||
+ | - [[HAEM5:Hyperplasias arising in immune deficiency/dysregulation]] | ||
+ | - [[HAEM5:Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation ]] | ||
+ | - [[HAEM5:EBV-positive mucocutaneous ulcer]] | ||
+ | - [[HAEM5:Lymphomas arising in immune deficiency / dysregulation ]] | ||
+ | - [[HAEM5:Inborn error of immunity-associated lymphoid proliferations and lymphomas]] | ||
+ | |||
+ | '''Hodgkin lymphoma''' | ||
+ | - [[HAEM5:Classic Hodgkin lymphoma ]] | ||
+ | - [[HAEM5:Nodular lymphocyte predominant Hodgkin lymphoma]] | ||
+ | |||
+ | '''Plasma cell neoplasms and other diseases with paraproteins''' | ||
+ | ''Monoclonal gammopathies'' | ||
+ | - [[HAEM5:Cold agglutinin disease ]] | ||
+ | - [[HAEM5:IgM monoclonal gammopathy of undetermined significance]] | ||
+ | - [[HAEM5:Non-IgM monoclonal gammopathy of undetermined significance]] | ||
+ | - [[HAEM5:Monoclonal gammopathy of renal significance]] | ||
+ | ''Diseases with monoclonal immunoglobulin deposition'' | ||
+ | - [[HAEM5:Immunoglobulin-related (AL) amyloidosis]] | ||
+ | - [[HAEM5:Monoclonal immunoglobulin deposition disease]] | ||
+ | ''Heavy chain diseases'' | ||
+ | - [[HAEM5:Mu heavy chain disease]] | ||
+ | - [[HAEM5:Gamma heavy chain disease]] | ||
+ | - [[HAEM5:Alpha heavy chain disease]] | ||
+ | ''Plasma cell neoplasms'' | ||
+ | - [[HAEM5:Plasmacytoma]] | ||
+ | - [[HAEM5:Plasma cell myeloma / multiple myeloma]] | ||
+ | - [[HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome]] | ||
+ | ==T-cell and NK-cell lymphoid proliferations and lymphomas== | ||
+ | |||
+ | '''Tumour-like lesions with T-cell predominance''' | ||
+ | - [[HAEM5:Kikuchi-Fujimoto disease]] | ||
+ | - [[HAEM5:Autoimmune lymphoproliferative syndrome]] | ||
+ | - [[HAEM5:Indolent T-lymphoblastic proliferation]] | ||
+ | |||
+ | '''Precursor T-cell neoplasms''' | ||
+ | ''T-lymphoblastic leukaemia / lymphoma'' | ||
+ | - [[HAEM5:T-lymphoblastic leukaemia / lymphoma, NOS]] | ||
+ | - [[HAEM5:Early T-precursor lymphoblastic leukaemia / lymphoma ]] | ||
+ | |||
+ | '''Mature T-cell and NK-cell neoplasms''' | ||
+ | ''Mature T-cell and NK-cell leukaemias'' | ||
+ | - [[HAEM5:T-prolymphocytic leukaemia]] | ||
+ | - [[HAEM5:T-large granular lymphocytic leukaemia]] | ||
+ | - [[HAEM5:NK-large granular lymphocytic leukaemia]] | ||
+ | - [[HAEM5:Adult T-cell leukaemia/lymphoma]] | ||
+ | - [[HAEM5:Sezary syndrome]] | ||
+ | - [[HAEM5:Aggressive NK-cell leukaemia]] | ||
+ | ''Primary cutaneous T-cell lymphoid proliferations and lymphomas'' | ||
+ | - [[HAEM5:Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder]] | ||
+ | - [[HAEM5:Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder]] | ||
+ | - [[HAEM5:Mycosis fungoides]] | ||
+ | - [[HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis]] | ||
+ | - [[HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma]] | ||
+ | - [[HAEM5:Subcutaneous panniculitis-like T-cell lymphoma]] | ||
+ | - [[HAEM5:Primary cutaneous gamma/delta T-cell lymphoma]] | ||
+ | - [[HAEM5:Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma]] | ||
+ | - [[HAEM5:Primary cutaneous peripheral T-cell lymphoma, NOS]] | ||
+ | ''Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas'' | ||
+ | - [[HAEM5:Indolent T-cell lymphoma of the gastrointestinal tract]] | ||
+ | - [[HAEM5:Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract]] | ||
+ | - [[HAEM5:Enteropathy-associated T-cell lymphoma]] | ||
+ | - [[HAEM5:Monomorphic epitheliotropic intestinal T-cell lymphoma]] | ||
+ | - [[HAEM5:Intestinal T-cell lymphoma, NOS]] | ||
+ | ''Hepatosplenic T-cell lymphoma'' | ||
+ | - [[HAEM5:Hepatosplenic T-cell lymphoma]] | ||
+ | ''Anaplastic large cell lymphoma'' | ||
+ | - [[HAEM5:ALK-positive anaplastic large cell lymphoma]] | ||
+ | - [[HAEM5:ALK-negative anaplastic large cell lymphoma]] | ||
+ | - [[HAEM5:Breast implant-associated anaplastic large cell lymphoma]] | ||
+ | ''Nodal T-follicular helper (TFH) cell lymphoma'' | ||
+ | - [[HAEM5:Nodal TFH cell lymphoma, angioimmunoblastic-type]] | ||
+ | - [[HAEM5:Nodal TFH cell lymphoma, follicular-type]] | ||
+ | - [[HAEM5:Nodal TFH cell lymphoma, NOS]] | ||
+ | ''Other peripheral T-cell lymphomas'' | ||
+ | - [[HAEM5:Peripheral T-cell lymphoma, NOS]] | ||
+ | ''EBV-positive NK-cell and T-cell lymphomas'' | ||
+ | - [[HAEM5:EBV-positive nodal T- and NK-cell lymphoma]] | ||
+ | - [[HAEM5:Extranodal NK/T-cell lymphoma]] | ||
+ | ''EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood'' | ||
+ | - [[HAEM5:Severe mosquito bite allergy]] | ||
+ | - [[HAEM5:Hydroa vacciniforme lymphoproliferative disorder]] | ||
+ | - [[HAEM5:Systemic chronic active EBV disease]] | ||
+ | - [[HAEM5:Systemic EBV-positive T-cell lymphoma of childhood]] | ||
+ | ==Stroma-derived neoplasms of lymphoid tissues== | ||
+ | |||
+ | '''Mesenchymal dendritic cell neoplasms''' | ||
+ | ''Follicular dendritic cell neoplasms'' | ||
+ | - [[HAEM5:Follicular dendritic cell sarcoma]] | ||
+ | - [[HAEM5:EBV-positive inflammatory follicular dendritic cell sarcoma]] | ||
+ | - [[HAEM5:Fibroblastic reticular cell tumour]] | ||
+ | |||
+ | '''Myofibroblastic tumours''' | ||
+ | ''Myofibroblastic tumour'' | ||
+ | - [[HAEM5:Intranodal palisaded myofibroblastoma]] | ||
+ | |||
+ | '''Spleen-specific vascular-stromal tumours''' | ||
+ | ''Splenic vascular-stromal tumours'' | ||
+ | - [[HAEM5:Littoral cell angioma]] | ||
+ | - [[HAEM5:Splenic hamartoma]] | ||
+ | - [[HAEM5:Sclerosing angiomatoid nodular transformation (SANT) of spleen]] | ||
+ | ==Genetic tumour syndromes== | ||
+ | - [[HAEM5:Fanconi anaemia]] | ||
+ | - [[HAEM5:Bloom syndrome]] | ||
+ | - [[HAEM5:Ataxia-telangiectasia syndrome]] | ||
+ | - [[HAEM5:RASopathies]] |
Latest revision as of 16:21, 3 November 2023
Myeloid proliferations and neoplasms
Myeloid precursor lesions Clonal Haematopoiesis - HAEM5:Clonal haematopoiesis - HAEM5:Clonal cytopenias of undetermined significance
Myeloproliferative neoplasms Myeloproliferative neoplasms - HAEM5:Chronic myeloid leukaemia - HAEM5:Chronic neutrophilic leukaemia - HAEM5:Chronic eosinophilic leukaemia - HAEM5:Polycythaemia vera - HAEM5:Essential thrombocythaemia - HAEM5:Primary myelofibrosis - HAEM5:Juvenile myelomonocytic leukaemia - HAEM5:Myeloproliferative neoplasm, NOS
Mastocytosis - HAEM5:Cutaneous mastocytosis - HAEM5:Systemic mastocytosis - HAEM5:Mast cell sarcoma
Myelodysplastic neoplasms Myelodysplastic neoplasms, with defining genetic abnormalities - HAEM5:Myelodysplastic neoplasm with low blasts and 5q deletion - HAEM5:Myelodysplastic neoplasm with low blasts and SF3B1 mutation - HAEM5:Myelodysplastic neoplasm with biallelic TP53 inactivation Myelodysplastic neoplasms, morphologically defined - HAEM5:Myelodysplastic neoplasm with low blasts - HAEM5:Myelodysplastic neoplasm, hypoplastic - HAEM5:Myelodysplastic neoplasm with increased blasts Myelodysplastic neoplasms of childhood - HAEM5:Childhood myelodysplastic neoplasm with low blasts - HAEM5:Childhood myelodysplastic neoplasm with increased blasts
Myelodysplastic/myeloproliferative neoplasms - HAEM5:Chronic myelomonocytic leukaemia - HAEM5:Myelodysplastic/myeloproliferative neoplasm with neutrophilia - HAEM5:Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis - HAEM5:Myelodysplastic/myeloproliferative neoplasm, NOS
Acute myeloid leukaemia Acute myeloid leukaemia with defining genetic abnormalities - HAEM5:Acute promyelocytic leukaemia with PML::RARA fusion - HAEM5:Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion - HAEM5:Acute myeloid leukaemia with CBFB::MYH11 fusion - HAEM5:Acute myeloid leukaemia with DEK::NUP214 fusion - HAEM5:Acute myeloid leukaemia with RBM15::MRTFA fusion - HAEM5:Acute myeloid leukaemia with BCR::ABL1 fusion - HAEM5:Acute myeloid leukaemia with KMT2A rearrangement - HAEM5:Acute myeloid leukaemia with MECOM rearrangement - HAEM5:Acute myeloid leukaemia with NUP98 rearrangement - HAEM5:Acute myeloid leukaemia with NPM1 mutation - HAEM5:Acute myeloid leukaemia with CEBPA mutation - HAEM5:Acute myeloid leukaemia, myelodysplasia-related - HAEM5:Acute myeloid leukaemia with other defined genetic alterations Acute myeloid leukaemia, defined by differentiation - HAEM5:Acute myeloid leukaemia with minimal differentiation - HAEM5:Acute myeloid leukaemia without maturation - HAEM5:Acute myeloid leukaemia with maturation - HAEM5:Acute basophilic leukaemia - HAEM5:Acute myelomonocytic leukaemia - HAEM5:Acute monocytic leukaemia - HAEM5:Acute erythroid leukaemia - HAEM5:Acute megakaryoblastic leukaemia Myeloid sarcoma - HAEM5:Myeloid sarcoma
Myeloid neoplasms, secondary Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions - HAEM5:Myeloid neoplasm post cytotoxic therapy - HAEM5:Myeloid neoplasms associated with germline predisposition - HAEM5:Myeloid proliferations associated with Down syndrome
Myeloid/lymphoid neoplasms Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement - HAEM5:Myeloid/lymphoid neoplasm with PDGFRA rearrangement - HAEM5:Myeloid/lymphoid neoplasm with PDGFRB rearrangement - HAEM5:Myeloid/lymphoid neoplasm with FGFR1 rearrangement - HAEM5:Myeloid/lymphoid neoplasm with JAK2 rearrangement - HAEM5:Myeloid/lymphoid neoplasm with FLT3 rearrangement - HAEM5:Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion - HAEM5:Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes
Acute leukaemias of mixed or ambiguous lineage Acute leukaemia of ambiguous lineage with defining genetic abnormalities - HAEM5:Mixed-phenotype acute leukaemia with BCR::ABL1 fusion - HAEM5:Mixed-phenotype acute leukaemia with KMT2A rearrangement - HAEM5:Acute leukaemia of ambiguous lineage with other defined genetic alterations Acute leukaemia of ambiguous lineage, immunophenotypically defined - HAEM5:Mixed-phenotype acute leukaemia, B/myeloid - HAEM5:Mixed-phenotype acute leukaemia, T/myeloid - HAEM5:Mixed-phenotype acute leukaemia, rare types - HAEM5:Acute leukaemia of ambiguous lineage, NOS - HAEM5:Acute undifferentiated leukaemia
Histiocytic/Dendritic cell neoplasms
Plasmacytoid dendritic cell neoplasms Plasmacytoid dendritic cell neoplasms - HAEM5:Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm - HAEM5:Blastic plasmacytoid dendritic cell neoplasm
Langerhans cell and other dendritic cell neoplasms Langerhans cells neoplasms - HAEM5:Langerhans cell histiocytosis - HAEM5:Langerhans cell sarcoma Other dendritic cell neoplasms - HAEM5:Indeterminate dendritic cell tumour - HAEM5:Interdigitating dendritic cell sarcoma
Histiocyte/macrophage neoplasms Histiocytic neoplasms - HAEM5:Juvenile xanthogranuloma - HAEM5:Erdheim-Chester disease - HAEM5:Rosai-Dorfman Disease - HAEM5:ALK-positive histiocytosis - HAEM5:Histiocytic sarcoma
B-cell lymphoid proliferations and lymphomas
Tumour like lesions with B-cell predominance - HAEM5:Reactive B-cell rich lymphoid proliferations that can mimic lymphoma - HAEM5:IgG4-related disease - HAEM5:Unicentric Castleman disease - HAEM5:Idiopathic multicentric Castleman disease - HAEM5:KSHV/HHV8-associated multicentric Castleman disease
Precursor B-cell neoplasms B-lymphoblastic leukaemias/lymphomas - HAEM5:B-lymphoblastic leukaemia/lymphoma - HAEM5:B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy - HAEM5:B-lymphoblastic leukaemia/lymphoma with hypodiploidy - HAEM5:B-lymphoblastic leukaemia/lymphoma with iAMP21 - HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion - HAEM5:B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features - HAEM5:B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement - HAEM5:B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion - HAEM5:B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features - HAEM5:B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion - HAEM5:B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion - HAEM5:B lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion - HAEM5:B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations - HAEM5:B-lymphoblastic leukaemia/lymphoma, NOS
Mature B-cell neoplasms Pre-neoplastic and neoplastic small lymphocytic proliferations - HAEM5:Monoclonal B-cell lymphocytosis - HAEM5:Chronic lymphocytic leukaemia/small lymphocytic lymphoma Splenic B-cell lymphomas and leukaemias - HAEM5:Hairy cell leukaemia - HAEM5:Splenic marginal zone lymphoma - HAEM5:Splenic diffuse red pulp small B-cell lymphoma - HAEM5:Splenic B-cell lymphoma/leukaemia with prominent nucleoli Lymphoplasmacytic lymphoma - HAEM5:Lymphoplasmacytic lymphoma Marginal zone lymphoma - HAEM5:Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue - HAEM5:Primary cutaneous marginal zone lymphoma - HAEM5:Nodal marginal zone lymphoma - HAEM5:Paediatric nodal marginal zone lymphoma Follicular lymphoma - HAEM5:In situ follicular B-cell neoplasm - HAEM5:Follicular lymphoma - HAEM5:Paediatric-type follicular lymphoma - HAEM5:Duodenal-type follicular lymphoma Cutaneous follicle centre lymphoma - HAEM5:Primary cutaneous follicle centre lymphoma Mantle cell lymphoma - HAEM5:In situ mantle cell neoplasm - HAEM5:Mantle cell lymphoma - HAEM5:Leukaemic non-nodal mantle cell lymphoma Transformations of indolent B-cell lymphomas - HAEM5:Transformations of indolent B-cell lymphomas Large B-cell lymphomas - HAEM5:Diffuse large B-cell lymphoma, NOS - HAEM5:T-cell/histiocyte-rich large B-cell lymphoma - HAEM5:Diffuse large B-cell lymphoma / high grade B-cell lymphoma with MYC and BCL2 rearrangements - HAEM5:ALK-positive large B-cell lymphoma - HAEM5:Large B-cell lymphoma with IRF4 rearrangement - HAEM5:High grade B-cell lymphoma with 11q aberrations - HAEM5:Lymphomatoid granulomatosis - HAEM5:EBV-positive diffuse large B-cell lymphoma - HAEM5:Diffuse large B-cell lymphoma associated with chronic inflammation - HAEM5:Fibrin-associated large B-cell lymphoma - HAEM5:Fluid overload-associated large B-cell lymphoma - HAEM5:Plasmablastic lymphoma - HAEM5:Primary large B-cell lymphoma of immune-privileged sites - HAEM5:Primary cutaneous diffuse large B-cell lymphoma, leg type - HAEM5:Intravascular large B-cell lymphoma - HAEM5:Primary mediastinal large B-cell lymphoma - HAEM5:Mediastinal grey zone lymphoma - HAEM5:High-grade B-cell lymphoma, NOS Burkitt lymphoma - HAEM5:Burkitt lymphoma KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas - HAEM5:Primary effusion lymphoma - HAEM5:KSHV/HHV8-positive diffuse large B-cell lymphoma - HAEM5:KSHV/HHV8-positive germinotropic lymphoproliferative disorder Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation - HAEM5:Hyperplasias arising in immune deficiency/dysregulation - HAEM5:Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation - HAEM5:EBV-positive mucocutaneous ulcer - HAEM5:Lymphomas arising in immune deficiency / dysregulation - HAEM5:Inborn error of immunity-associated lymphoid proliferations and lymphomas
Hodgkin lymphoma - HAEM5:Classic Hodgkin lymphoma - HAEM5:Nodular lymphocyte predominant Hodgkin lymphoma
Plasma cell neoplasms and other diseases with paraproteins Monoclonal gammopathies - HAEM5:Cold agglutinin disease - HAEM5:IgM monoclonal gammopathy of undetermined significance - HAEM5:Non-IgM monoclonal gammopathy of undetermined significance - HAEM5:Monoclonal gammopathy of renal significance Diseases with monoclonal immunoglobulin deposition - HAEM5:Immunoglobulin-related (AL) amyloidosis - HAEM5:Monoclonal immunoglobulin deposition disease Heavy chain diseases - HAEM5:Mu heavy chain disease - HAEM5:Gamma heavy chain disease - HAEM5:Alpha heavy chain disease Plasma cell neoplasms - HAEM5:Plasmacytoma - HAEM5:Plasma cell myeloma / multiple myeloma - HAEM5:Plasma cell neoplasms with associated paraneoplastic syndrome
T-cell and NK-cell lymphoid proliferations and lymphomas
Tumour-like lesions with T-cell predominance - HAEM5:Kikuchi-Fujimoto disease - HAEM5:Autoimmune lymphoproliferative syndrome - HAEM5:Indolent T-lymphoblastic proliferation
Precursor T-cell neoplasms T-lymphoblastic leukaemia / lymphoma - HAEM5:T-lymphoblastic leukaemia / lymphoma, NOS - HAEM5:Early T-precursor lymphoblastic leukaemia / lymphoma
Mature T-cell and NK-cell neoplasms Mature T-cell and NK-cell leukaemias - HAEM5:T-prolymphocytic leukaemia - HAEM5:T-large granular lymphocytic leukaemia - HAEM5:NK-large granular lymphocytic leukaemia - HAEM5:Adult T-cell leukaemia/lymphoma - HAEM5:Sezary syndrome - HAEM5:Aggressive NK-cell leukaemia Primary cutaneous T-cell lymphoid proliferations and lymphomas - HAEM5:Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder - HAEM5:Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder - HAEM5:Mycosis fungoides - HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis - HAEM5:Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma - HAEM5:Subcutaneous panniculitis-like T-cell lymphoma - HAEM5:Primary cutaneous gamma/delta T-cell lymphoma - HAEM5:Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma - HAEM5:Primary cutaneous peripheral T-cell lymphoma, NOS Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas - HAEM5:Indolent T-cell lymphoma of the gastrointestinal tract - HAEM5:Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract - HAEM5:Enteropathy-associated T-cell lymphoma - HAEM5:Monomorphic epitheliotropic intestinal T-cell lymphoma - HAEM5:Intestinal T-cell lymphoma, NOS Hepatosplenic T-cell lymphoma - HAEM5:Hepatosplenic T-cell lymphoma Anaplastic large cell lymphoma - HAEM5:ALK-positive anaplastic large cell lymphoma - HAEM5:ALK-negative anaplastic large cell lymphoma - HAEM5:Breast implant-associated anaplastic large cell lymphoma Nodal T-follicular helper (TFH) cell lymphoma - HAEM5:Nodal TFH cell lymphoma, angioimmunoblastic-type - HAEM5:Nodal TFH cell lymphoma, follicular-type - HAEM5:Nodal TFH cell lymphoma, NOS Other peripheral T-cell lymphomas - HAEM5:Peripheral T-cell lymphoma, NOS EBV-positive NK-cell and T-cell lymphomas - HAEM5:EBV-positive nodal T- and NK-cell lymphoma - HAEM5:Extranodal NK/T-cell lymphoma EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood - HAEM5:Severe mosquito bite allergy - HAEM5:Hydroa vacciniforme lymphoproliferative disorder - HAEM5:Systemic chronic active EBV disease - HAEM5:Systemic EBV-positive T-cell lymphoma of childhood
Stroma-derived neoplasms of lymphoid tissues
Mesenchymal dendritic cell neoplasms Follicular dendritic cell neoplasms - HAEM5:Follicular dendritic cell sarcoma - HAEM5:EBV-positive inflammatory follicular dendritic cell sarcoma - HAEM5:Fibroblastic reticular cell tumour
Myofibroblastic tumours Myofibroblastic tumour - HAEM5:Intranodal palisaded myofibroblastoma
Spleen-specific vascular-stromal tumours Splenic vascular-stromal tumours - HAEM5:Littoral cell angioma - HAEM5:Splenic hamartoma - HAEM5:Sclerosing angiomatoid nodular transformation (SANT) of spleen
Genetic tumour syndromes
- HAEM5:Fanconi anaemia - HAEM5:Bloom syndrome - HAEM5:Ataxia-telangiectasia syndrome - HAEM5:RASopathies