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- 1 member (0 subcategories, 0 files) - 11:29, 15 January 2021
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- ...ollaborative project to document and describe chromosome and other genomic abnormalities in cancer. This resource is supported by the [http://www.cancergenomics.org ...es V|V]]''' | '''[[:Category:Diseases W|W]]''' | '''[[:Category:Diseases X|X]]''' | '''[[:Category:Diseases Y|Y]]''' | '''[[:Category:Diseases Z|Z]]'''7 KB (905 words) - 22:59, 20 November 2017
- == Structural == * Structural Abnormalities10 KB (1,089 words) - 22:30, 20 November 2017
- ...inclusion in any of the other AML groups (i.e. AML with Recurrent Genetic Abnormalities, AML with Myelodysplasia-Related Changes, or Therapy-Related Myeloid Neopla ...3|issn=1528-0020|pmid=21474671}}</ref>. Rearrangement of MYB/GATA1 with t(X;6)(p11;q23) has been reported in four male infants<ref name=":4" /><ref nam11 KB (1,531 words) - 12:34, 3 November 2023
- ...et al., (2017). B-Lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic a ...the general population. Additionally, patients with a constitutional ring chromosome 21, r(21), may potentially be predisposed to iAMP21 ALL.<ref name=":1" />12 KB (1,705 words) - 12:38, 3 November 2023
- ...">Arber DA, et al., (2017). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic a ...cal fusions are expressed, the ''RBM15''-''MKL1'' fusion on the derivative chromosome 22 is the candidate oncoprotein because it contains all of the putative fun10 KB (1,334 words) - 12:32, 3 November 2023
- ...in >50 chromosome (usually <66), typically without translocations or other structural alterations. ...tology|volume=99|issue=1|pages=93–100|doi=10.1046/j.1365-2141.1997.3493163.x|issn=0007-1048|pmid=9359508}}</ref> <ref>{{Cite journal|last=Reismüller|fi16 KB (2,198 words) - 12:37, 3 November 2023
- ...in >50 chromosome (usually <66), typically without translocations or other structural alterations. ...tology|volume=99|issue=1|pages=93–100|doi=10.1046/j.1365-2141.1997.3493163.x|issn=0007-1048|pmid=9359508}}</ref> <ref>{{Cite journal|last=Reismüller|fi17 KB (2,231 words) - 13:48, 3 November 2023
- ...ique L.|last2=van Slegtenhorst|first2=Marjon|last3=De Menezes|first3=Renée X.|last4=Cheok|first4=Meyling H.|last5=Buijs-Gladdines|first5=Jessica G. C. A ...p A.|last9=Bräundl|first9=Kathrin|date=2017|title=Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutati19 KB (2,670 words) - 12:38, 3 November 2023
- ...et al., (2017). B-Lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic a ...the general population. Additionally, patients with a constitutional ring chromosome 21, r(21), may potentially be predisposed to iAMP21 ALL.<ref name=":1" />12 KB (1,721 words) - 13:49, 3 November 2023
- ...in >50 chromosome (usually <66), typically without translocations or other structural alterations. ...tology|volume=99|issue=1|pages=93–100|doi=10.1046/j.1365-2141.1997.3493163.x|issn=0007-1048|pmid=9359508}}</ref> <ref>{{Cite journal|last=Reismüller|fi24 KB (3,252 words) - 14:20, 13 December 2023
- ...et al., (2017). B-Lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic a ...the general population. Additionally, patients with a constitutional ring chromosome 21, r(21), may potentially be predisposed to iAMP21 ALL.<ref name=":0" />14 KB (2,044 words) - 10:09, 27 February 2024
- Somatic Structural variants of translocation: |t(2,x)(p22.3/p22.12)17 KB (2,353 words) - 12:42, 3 November 2023
- Somatic Structural variants of translocation: |t(2,x)(p22.3/p22.12)17 KB (2,397 words) - 16:35, 4 December 2023
- ...gression, see the table below for the more commonly implicated cytogenetic abnormalities. !Chromosome Number!!Gain/Loss/Amp/LOH!!Region24 KB (3,493 words) - 12:46, 3 November 2023
- ...mphoblastic leukemias. The majority of cases (>80%) fall within the 44-45 chromosome range. However, beyond this, there are three main groups, that although ra ...edscape Article, Drugs & Diseases, Hematology.</ref>. Hypodiploid ALL with chromosome numbers less than 44 is associated with poor prognosis.21 KB (2,882 words) - 12:37, 3 November 2023
- ...mphoblastic leukemias. The majority of cases (>80%) fall within the 44-45 chromosome range. However, beyond this, there are three main groups, that although ra ...edscape Article, Drugs & Diseases, Hematology.</ref>. Hypodiploid ALL with chromosome numbers less than 44 is associated with poor prognosis.21 KB (2,915 words) - 13:48, 3 November 2023
- |Fusions involving ''MYB'' with other gene partners or complex structural abnormalities associated with ''MYB'' gene fusion generate more complex karyotypes. Loss ...ns involving ''MYBL1'' with other gene partners or more complex structural abnormalities associated with ''MYBL1'' gene fusion generate more complex karyotypes. Oth19 KB (2,737 words) - 13:17, 29 February 2024
- ...gression, see the table below for the more commonly implicated cytogenetic abnormalities. !Chromosome Number!!Gain/Loss/Amp/LOH!!Region24 KB (3,499 words) - 16:37, 4 December 2023
- |These genetic abnormalities serve as diagnostic markers and generally indicate an aggressive disease. T |t(X;14)(q28;q11.2)16 KB (2,286 words) - 20:51, 9 May 2024
- ...Options in Oncology|volume=20|issue=1|pages=9|doi=10.1007/s11864-019-0605-x|issn=1534-6277|pmid=30715612}}</ref>. ...et age and shorter median survival<ref name=":5" />. ''RUNX2'', located on chromosome 6p21, is strongly expressed in pDCs and BPDCN cells. The t(6,8) generates m17 KB (2,329 words) - 12:35, 3 November 2023