Search results

• HAEM4Backup:Blastic Plasmacytoid Dendritic Cell Neoplasm
  ....gov/pubmed/30350260|journal=Current Hematologic Malignancy Reports|volume=13|issue=6|pages=477–483|doi=10.1007/s11899-018-0489-z|issn=1558-822X|pmid=3 ...et age and shorter median survival<ref name=":5" />. ''RUNX2'', located on chromosome 6p21, is strongly expressed in pDCs and BPDCN cells. The t(6,8) generates m
  17 KB (2,329 words) - 12:35, 3 November 2023
• HAEM4:Blastic Plasmacytoid Dendritic Cell Neoplasm
  ....gov/pubmed/30350260|journal=Current Hematologic Malignancy Reports|volume=13|issue=6|pages=477–483|doi=10.1007/s11899-018-0489-z|issn=1558-822X|pmid=3 ...et age and shorter median survival<ref name=":5" />. ''RUNX2'', located on chromosome 6p21, is strongly expressed in pDCs and BPDCN cells. The t(6,8) generates m
  17 KB (2,369 words) - 13:47, 3 November 2023
• BRST5:Adenoid Cystic Carcinoma
  ...nih.gov/31105427|journal=Breast Cancer: Basic and Clinical Research|volume=13|pages=1178223419842185|doi=10.1177/1178223419842185|issn=1178-2234|pmc=6501 |Fusions involving ''MYB'' with other gene partners or complex structural abnormalities associated with ''MYB'' gene fusion generate more complex karyotypes. Loss
  19 KB (2,737 words) - 13:17, 29 February 2024
• HAEM5:B-lymphoblastic leukaemia/lymphoma with hypodiploidy
  ...mphoblastic leukemias. The majority of cases (>80%) fall within the 44-45 chromosome range. However, beyond this, there are three main groups, that although ra ...edscape Article, Drugs & Diseases, Hematology.</ref>. Hypodiploid ALL with chromosome numbers less than 44 is associated with poor prognosis.
  30 KB (4,118 words) - 14:20, 13 December 2023
• HAEM4:Acute Myeloid Leukemia (AML) with BCR-ABL1
  ...ion. The t(9:22)(q34.1;q11.2) results in the formation of the Philadelphia chromosome and the chimeric BCR-ABL1 fusion gene. It is worth noting that the fusion g ...there are only a few cases described where acquisition of the Philadelphia chromosome upon disease relapse or transformation of antecedent myelodysplastic syndro
  18 KB (2,576 words) - 13:45, 3 November 2023
• HAEM4Backup:Anaplastic Large Cell Lymphoma, ALK-Negative
  ...ac|date=2012-09-13|title=Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas|url=http ...rst9=Kip|date=2012|title=Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas|url=http
  23 KB (3,346 words) - 12:52, 3 November 2023
• HAEM4:Anaplastic Large Cell Lymphoma, ALK-Negative
  ...ac|date=2012-09-13|title=Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas|url=http ...rst9=Kip|date=2012|title=Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas|url=http
  24 KB (3,388 words) - 16:41, 4 December 2023
• HAEM4Backup:High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)
  .... Jeffrey|date=2015-02|title=B-cell lymphomas with concurrent MYC and BCL2 abnormalities other than translocations behave similarly to MYC/BCL2 double-hit lymphomas ...pical immunophenotype (e.g. diffuse and strong BCL2 expression) or genetic abnormalities (e.g. a complex karyotype) are present<ref name=":0" /><ref name=":4">{{Cit
  17 KB (2,506 words) - 12:47, 3 November 2023
• HAEM5:Blastic plasmacytoid dendritic cell neoplasm
  ....gov/pubmed/30350260|journal=Current Hematologic Malignancy Reports|volume=13|issue=6|pages=477–483|doi=10.1007/s11899-018-0489-z|issn=1558-822X|pmid=3 ...et age and shorter median survival<ref name=":5" />. ''RUNX2'', located on chromosome 6p21, is strongly expressed in pDCs and BPDCN cells. The t(6,8) generates m
  26 KB (3,637 words) - 14:21, 13 December 2023
• HAEM4:High-Grade B-cell Lymphoma, Not Otherwise Specified (NOS)
  .... Jeffrey|date=2015-02|title=B-cell lymphomas with concurrent MYC and BCL2 abnormalities other than translocations behave similarly to MYC/BCL2 double-hit lymphomas ...pical immunophenotype (e.g. diffuse and strong BCL2 expression) or genetic abnormalities (e.g. a complex karyotype) are present<ref name=":0" /><ref name=":4">{{Cit
  18 KB (2,549 words) - 16:38, 4 December 2023
• HAEM5:T-prolymphocytic leukaemia
  |These genetic abnormalities serve as diagnostic markers and generally indicate an aggressive disease. T ...frequent changes are deletions in 12p13 and 22q, gains in 8q24 (MYC), and abnormalities in chromosomes 5p, 6, and 17.
  17 KB (2,392 words) - 14:32, 15 May 2024
• HAEM5:ALK-negative anaplastic large cell lymphoma
  ...ac|date=2012-09-13|title=Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas|url=http ...rst9=Kip|date=2012|title=Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas|url=http
  32 KB (4,584 words) - 14:16, 13 December 2023
• HAEM5:Acute myeloid leukaemia with BCR::ABL1 fusion
  ...ion. The t(9:22)(q34.1;q11.2) results in the formation of the Philadelphia chromosome and the chimeric BCR-ABL1 fusion gene. It is worth noting that the fusion g ...there are only a few cases described where acquisition of the Philadelphia chromosome upon disease relapse or transformation of antecedent myelodysplastic syndro
  26 KB (3,785 words) - 14:16, 13 December 2023
• CNS5:Ganglioglioma
  ...st2=K.|last3=Comair|first3=Y. G.|date=1995-07|title=Cortical architectural abnormalities and MIB1 immunoreactivity in gangliogliomas: a study of 60 patients with in ...st2=K.|last3=Comair|first3=Y. G.|date=1995-07|title=Cortical architectural abnormalities and MIB1 immunoreactivity in gangliogliomas: a study of 60 patients with in
  23 KB (3,102 words) - 13:55, 25 February 2024
• HAEM4Backup:Waldenstrom Macroglobulinemia
  ....nlm.nih.gov/23474147|journal=Clinical Lymphoma, Myeloma & Leukemia|volume=13|issue=2|pages=244–246|doi=10.1016/j.clml.2013.02.001|issn=2152-2669|pmid= ...s in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia. Chromosomal abnormalities are associated with the polymorphous subtype and an aggressive clinical cou
  35 KB (4,909 words) - 12:40, 3 November 2023
• HAEM5:High-grade B-cell lymphoma, NOS
  .... Jeffrey|date=2015-02|title=B-cell lymphomas with concurrent MYC and BCL2 abnormalities other than translocations behave similarly to MYC/BCL2 double-hit lymphomas ...pical immunophenotype (e.g. diffuse and strong BCL2 expression) or genetic abnormalities (e.g. a complex karyotype) are present<ref name=":0" /><ref name=":4">{{Cit
  26 KB (3,680 words) - 14:26, 13 December 2023
• HAEM4Backup:Intravascular Large B-cell Lymphoma
  ...ging. Radiological findings are often non-specific, but frequently include abnormalities if the central nervous system is imaged using MRI, including hyperintense l ...of three cases of IVLBCL and a literature review, Khoury et al<ref name=":13" /> described case reports of breakpoints involving BCL6, CMYC, PAX5, BCL1,
  46 KB (6,456 words) - 12:45, 3 November 2023
• HAEM4:Waldenstrom Macroglobulinemia
  ....nlm.nih.gov/23474147|journal=Clinical Lymphoma, Myeloma & Leukemia|volume=13|issue=2|pages=244–246|doi=10.1016/j.clml.2013.02.001|issn=2152-2669|pmid= ...s in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia. Chromosomal abnormalities are associated with the polymorphous subtype and an aggressive clinical cou
  35 KB (4,949 words) - 16:33, 4 December 2023
• HAEM4:Intravascular Large B-cell Lymphoma
  ...ging. Radiological findings are often non-specific, but frequently include abnormalities if the central nervous system is imaged using MRI, including hyperintense l ...of three cases of IVLBCL and a literature review, Khoury et al<ref name=":13" /> described case reports of breakpoints involving BCL6, CMYC, PAX5, BCL1,
  46 KB (6,495 words) - 13:54, 3 November 2023
• HAEM5:Intravascular large B-cell lymphoma
  ...ging. Radiological findings are often non-specific, but frequently include abnormalities if the central nervous system is imaged using MRI, including hyperintense l ...of three cases of IVLBCL and a literature review, Khoury et al<ref name=":13" /> described case reports of breakpoints involving BCL6, CMYC, PAX5, BCL1,
  55 KB (7,745 words) - 14:29, 13 December 2023

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