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B-ALL Tables: Prognostic Genomic Abnormalities and Recurrent Gene Fusions (view source)
Revision as of 12:28, 22 July 2021
, 12:28, 22 July 2021adding a reference
'''Table 1 - Gene fusions reported in Ph-like B-ALL and other new B-ALL molecular subtypes (Literature Review)'''. Table derived from Akkari et al., 2020 [PMID 32302940] with permission from Cancer Genetics.
'''Table 1 - Gene fusions reported in Ph-like B-ALL and other new B-ALL molecular subtypes (Literature Review)'''. Table derived from Akkari et al., 2020 [PMID 32302940] with permission from Cancer Genetics. <ref>{{Cite journal|last=Akkari|first=Yassmine M. N.|last2=Bruyere|first2=Helene|last3=Hagelstrom|first3=R. Tanner|last4=Kanagal-Shamanna|first4=Rashmi|last5=Liu|first5=Jie|last6=Luo|first6=Minjie|last7=Mikhail|first7=Fady M.|last8=Pitel|first8=Beth A.|last9=Raca|first9=Gordana|date=2020-05|title=Evidence-based review of genomic aberrations in B-lymphoblastic leukemia/lymphoma: Report from the cancer genomics consortium working group for lymphoblastic leukemia|url=https://pubmed.ncbi.nlm.nih.gov/32302940|journal=Cancer Genetics|volume=243|pages=52–72|doi=10.1016/j.cancergen.2020.03.001|issn=2210-7762|pmid=32302940}}</ref>
{| class="wikitable"
{| class="wikitable"
|'''Subtype'''
|'''Subtype'''
|NO
|NO
|26859458
|26859458
|Inversion of chromosome 19 juxtaposes ''EPOR'' to the upstream region of ''LAIR1''
|Inversion of chromosome 19 juxtaposes ''EPOR'' to the upstream region of ''LAIR1''
|-
|-
|''THADA''
|''THADA''
|-
|-
| rowspan="22" |'''''JAK2''''' (9p24.1)
| rowspan="22" |'''''JAK2''''' (9p24.1)
|''ATF7IP''
|''ATF7IP''
|''RFX3''
|''RFX3''
|inv(9)(p24.1p24.2)
|inv(9)(p24.1p24.2)
|''RFX3-JAK2''
|''RFX3-JAK2''
|NO
|NO
|28408464
|28408464
|''USP25''
|''USP25''
|t(9;21)(p24.1;q21.1)
|t(9;21)(p24.1;q21.1)
|''USP25-JAK2''
|''USP25-JAK2''
|? YES
|? YES
|28408464
|28408464
|''SSBP2''
|''SSBP2''
|t(5;5)(q14.1;q32)
|t(5;5)(q14.1;q32)
|''SSBP2-PDGFRB''
|''SSBP2-PDGFRB''
|? YES
|? YES
|28972016
|28972016
|''TNIP1''
|''TNIP1''
|del(5)(q32q33.1)
|del(5)(q32q33.1)
|''TNIP1-PDGFRB''
|''TNIP1-PDGFRB''
|NO
|NO
|28972016
|28972016
|t(4;12)(q21.2;p13.3)
|t(4;12)(q21.2;p13.3)
|''BMP2K-ZNF384'' on der(4)
|''BMP2K-ZNF384'' on der(4)
|YES
|YES
|27634205
|27634205
|
|