Compendium of Cancer Genome Aberrations

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==Myeloid proliferations and neoplasms ([[Myeloid proliferations and neoplasms|Overview Page Link]])==
 
==Myeloid proliferations and neoplasms ([[Myeloid proliferations and neoplasms|Overview Page Link]])==
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Myeloid precursor lesions
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'''Myeloid precursor lesions'''
 
   ''Clonal Haematopoiesis''
 
   ''Clonal Haematopoiesis''
 
     - [[Clonal haematopoiesis]]
 
     - [[Clonal haematopoiesis]]
 
     - [[Clonal cytopenias of undetermined significance]]
 
     - [[Clonal cytopenias of undetermined significance]]
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===Myeloproliferative neoplasms===
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'''Myeloproliferative neoplasms
 
   ''Myeloproliferative neoplasms''
 
   ''Myeloproliferative neoplasms''
 
     - [[Chronic myeloid leukaemia]]
 
     - [[Chronic myeloid leukaemia]]
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     - [[Juvenile myelomonocytic leukaemia]]
 
     - [[Juvenile myelomonocytic leukaemia]]
 
     - [[Myeloproliferative neoplasm, NOS]]
 
     - [[Myeloproliferative neoplasm, NOS]]
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===Mastocytosis===
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 +
'''Mastocytosis'''
 
     - [[Cutaneous mastocytosis]]
 
     - [[Cutaneous mastocytosis]]
 
     - [[Systemic mastocytosis]]
 
     - [[Systemic mastocytosis]]
 
     - [[Mast cell sarcoma]]
 
     - [[Mast cell sarcoma]]
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===Myelodysplastic neoplasms===
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 +
'''Myelodysplastic neoplasms'''
 
   ''Myelodysplastic neoplasms, with defining genetic abnormalities''
 
   ''Myelodysplastic neoplasms, with defining genetic abnormalities''
 
     - [[Myelodysplastic neoplasm with low blasts and 5q deletion]]
 
     - [[Myelodysplastic neoplasm with low blasts and 5q deletion]]
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     - [[Childhood myelodysplastic neoplasm with low blasts]]
 
     - [[Childhood myelodysplastic neoplasm with low blasts]]
 
     - [[Childhood myelodysplastic neoplasm with increased blasts]]
 
     - [[Childhood myelodysplastic neoplasm with increased blasts]]
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===Myelodysplastic/myeloproliferative neoplasms===
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'''Myelodysplastic/myeloproliferative neoplasms'''
 
     - [[Chronic myelomonocytic leukaemia]]
 
     - [[Chronic myelomonocytic leukaemia]]
 
     - [[Myelodysplastic/myeloproliferative neoplasm with neutrophilia]]
 
     - [[Myelodysplastic/myeloproliferative neoplasm with neutrophilia]]
 
     - [[Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis]]
 
     - [[Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis]]
 
     - [[Myelodysplastic/myeloproliferative neoplasm, NOS]]
 
     - [[Myelodysplastic/myeloproliferative neoplasm, NOS]]
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===Acute myeloid leukaemia===
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'''Acute myeloid leukaemia'''
 
   ''Acute myeloid leukaemia with defining genetic abnormalities''
 
   ''Acute myeloid leukaemia with defining genetic abnormalities''
 
     - [[Acute promyelocytic leukaemia with PML::RARA fusion]]
 
     - [[Acute promyelocytic leukaemia with PML::RARA fusion]]
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   ''Myeloid sarcoma''
 
   ''Myeloid sarcoma''
 
     - [[Myeloid sarcoma]]
 
     - [[Myeloid sarcoma]]
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===Myeloid neoplasms, secondary===
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 +
'''Myeloid neoplasms, secondary'''
 
   ''Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions''
 
   ''Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions''
 
     - [[Myeloid neoplasm post cytotoxic therapy]]
 
     - [[Myeloid neoplasm post cytotoxic therapy]]
 
     - [[Myeloid neoplasms associated with germline predisposition]]
 
     - [[Myeloid neoplasms associated with germline predisposition]]
 
     - [[Myeloid proliferations associated with Down syndrome]]
 
     - [[Myeloid proliferations associated with Down syndrome]]
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===Myeloid/lymphoid neoplasms===
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 +
'''Myeloid/lymphoid neoplasms'''
 
   ''Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement''
 
   ''Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement''
 
     - [[Myeloid/lymphoid neoplasm with PDGFRA rearrangement]]
 
     - [[Myeloid/lymphoid neoplasm with PDGFRA rearrangement]]
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     - [[Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion]]
 
     - [[Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion]]
 
     - [[Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes]]
 
     - [[Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes]]
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===Acute leukaemias of mixed or ambiguous lineage===
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 +
'''Acute leukaemias of mixed or ambiguous lineage'''
 
   ''Acute leukaemia of ambiguous lineage with defining genetic abnormalities''
 
   ''Acute leukaemia of ambiguous lineage with defining genetic abnormalities''
 
     - [[Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]]
 
     - [[Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]]
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     - [[Acute undifferentiated leukaemia]]
 
     - [[Acute undifferentiated leukaemia]]
 
==Histiocytic/Dendritic cell neoplasms ([[Histiocytic/Dendritic cell neoplasms|Overview Page Link]])==
 
==Histiocytic/Dendritic cell neoplasms ([[Histiocytic/Dendritic cell neoplasms|Overview Page Link]])==
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===Plasmacytoid dendritic cell neoplasms===
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'''Plasmacytoid dendritic cell neoplasms'''
 
   ''Plasmacytoid dendritic cell neoplasms''
 
   ''Plasmacytoid dendritic cell neoplasms''
 
     - [[Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm]]
 
     - [[Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm]]
 
     - [[Blastic plasmacytoid dendritic cell neoplasm]]
 
     - [[Blastic plasmacytoid dendritic cell neoplasm]]
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===Langerhans cell and other dendritic cell neoplasms===
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'''Langerhans cell and other dendritic cell neoplasms'''
 
   ''Langerhans cells neoplasms''
 
   ''Langerhans cells neoplasms''
 
     - [[Langerhans cell histiocytosis]]
 
     - [[Langerhans cell histiocytosis]]
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     - [[Indeterminate dendritic cell tumour]]
 
     - [[Indeterminate dendritic cell tumour]]
 
     - [[Interdigitating dendritic cell sarcoma]]
 
     - [[Interdigitating dendritic cell sarcoma]]
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===Histiocyte/macrophage neoplasms===
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'''Histiocyte/macrophage neoplasms'''
 
   ''Histiocytic neoplasms''
 
   ''Histiocytic neoplasms''
 
     - [[Juvenile xanthogranuloma]]
 
     - [[Juvenile xanthogranuloma]]
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     - [[Histiocytic sarcoma]]
 
     - [[Histiocytic sarcoma]]
 
==B-cell lymphoid proliferations and lymphomas ([[B-cell lymphoid proliferations and lymphomas|Overview Page Link]])==
 
==B-cell lymphoid proliferations and lymphomas ([[B-cell lymphoid proliferations and lymphomas|Overview Page Link]])==
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===Tumour like lesions with B-cell predominance===
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'''Tumour like lesions with B-cell predominance'''
 
     - [[Reactive B-cell rich lymphoid proliferations that can mimic lymphoma]]
 
     - [[Reactive B-cell rich lymphoid proliferations that can mimic lymphoma]]
 
     - [[IgG4-related disease]]
 
     - [[IgG4-related disease]]
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     - [[Idiopathic multicentric Castleman disease]]
 
     - [[Idiopathic multicentric Castleman disease]]
 
     - [[KSHV/HHV8-associated multicentric Castleman disease]]
 
     - [[KSHV/HHV8-associated multicentric Castleman disease]]
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===Precursor B-cell neoplasms===
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'''Precursor B-cell neoplasms'''
 
   ''B-lymphoblastic leukaemias/lymphomas''
 
   ''B-lymphoblastic leukaemias/lymphomas''
 
     - [[B-lymphoblastic leukaemia/lymphoma]]
 
     - [[B-lymphoblastic leukaemia/lymphoma]]
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     - [[B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations]]
 
     - [[B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations]]
 
     - [[B-lymphoblastic leukaemia/lymphoma, NOS]]
 
     - [[B-lymphoblastic leukaemia/lymphoma, NOS]]
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===Mature B-cell neoplasms===
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'''Mature B-cell neoplasms'''
 
   ''Pre-neoplastic and neoplastic small lymphocytic proliferations ''
 
   ''Pre-neoplastic and neoplastic small lymphocytic proliferations ''
 
     - [[Monoclonal B-cell lymphocytosis]]
 
     - [[Monoclonal B-cell lymphocytosis]]
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     - [[Lymphomas arising in immune deficiency / dysregulation ]]
 
     - [[Lymphomas arising in immune deficiency / dysregulation ]]
 
     - [[Inborn error of immunity-associated lymphoid proliferations and lymphomas]]
 
     - [[Inborn error of immunity-associated lymphoid proliferations and lymphomas]]
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===Hodgkin lymphoma===
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'''Hodgkin lymphoma'''
 
     - [[Classic Hodgkin lymphoma ]]
 
     - [[Classic Hodgkin lymphoma ]]
 
     - [[Nodular lymphocyte predominant Hodgkin lymphoma]]
 
     - [[Nodular lymphocyte predominant Hodgkin lymphoma]]
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===Plasma cell neoplasms and other diseases with paraproteins===
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'''Plasma cell neoplasms and other diseases with paraproteins'''
 
   ''Monoclonal gammopathies''
 
   ''Monoclonal gammopathies''
 
     - [[Cold agglutinin disease ]]
 
     - [[Cold agglutinin disease ]]
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     - [[Alpha heavy chain disease]]
 
     - [[Alpha heavy chain disease]]
 
   ''Plasma cell neoplasms''
 
   ''Plasma cell neoplasms''
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     - [[Plasmacytoma]]
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     - [[HAEM5:Plasmacytoma]]
 
     - [[Plasma cell myeloma / multiple myeloma]]
 
     - [[Plasma cell myeloma / multiple myeloma]]
 
     - [[Plasma cell neoplasms with associated paraneoplastic syndrome]]
 
     - [[Plasma cell neoplasms with associated paraneoplastic syndrome]]
 
==T-cell and NK-cell lymphoid proliferations and lymphomas  ([[T-cell and NK-cell lymphoid proliferations and lymphomas |Overview Page Link]])==
 
==T-cell and NK-cell lymphoid proliferations and lymphomas  ([[T-cell and NK-cell lymphoid proliferations and lymphomas |Overview Page Link]])==
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===Tumour-like lesions with T-cell predominance===
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'''Tumour-like lesions with T-cell predominance'''
 
     - [[Kikuchi-Fujimoto disease]]
 
     - [[Kikuchi-Fujimoto disease]]
 
     - [[Autoimmune lymphoproliferative syndrome]]
 
     - [[Autoimmune lymphoproliferative syndrome]]
 
     - [[Indolent T-lymphoblastic proliferation]]
 
     - [[Indolent T-lymphoblastic proliferation]]
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===Precursor T-cell neoplasms===
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'''Precursor T-cell neoplasms'''
 
   ''T-lymphoblastic leukaemia / lymphoma''
 
   ''T-lymphoblastic leukaemia / lymphoma''
 
     - [[T-lymphoblastic leukaemia / lymphoma, NOS]]
 
     - [[T-lymphoblastic leukaemia / lymphoma, NOS]]
 
     - [[Early T-precursor lymphoblastic leukaemia / lymphoma ]]
 
     - [[Early T-precursor lymphoblastic leukaemia / lymphoma ]]
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===Mature T-cell and NK-cell neoplasms===
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'''Mature T-cell and NK-cell neoplasms'''
 
   ''Mature T-cell and NK-cell leukaemias''
 
   ''Mature T-cell and NK-cell leukaemias''
 
     - [[T-prolymphocytic leukaemia]]
 
     - [[T-prolymphocytic leukaemia]]
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     - [[Systemic EBV-positive T-cell lymphoma of childhood]]
 
     - [[Systemic EBV-positive T-cell lymphoma of childhood]]
 
==Stroma-derived neoplasms of lymphoid tissues ([[Stroma-derived neoplasms of lymphoid tissues|Overview Page Link]])==
 
==Stroma-derived neoplasms of lymphoid tissues ([[Stroma-derived neoplasms of lymphoid tissues|Overview Page Link]])==
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===Mesenchymal dendritic cell neoplasms===
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'''Mesenchymal dendritic cell neoplasms'''
 
   ''Follicular dendritic cell neoplasms''
 
   ''Follicular dendritic cell neoplasms''
 
     - [[Follicular dendritic cell sarcoma]]
 
     - [[Follicular dendritic cell sarcoma]]
 
     - [[EBV-positive inflammatory follicular dendritic cell sarcoma]]
 
     - [[EBV-positive inflammatory follicular dendritic cell sarcoma]]
 
     - [[Fibroblastic reticular cell tumour]]
 
     - [[Fibroblastic reticular cell tumour]]
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===Myofibroblastic tumours===
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'''Myofibroblastic tumours'''
 
   ''Myofibroblastic tumour''
 
   ''Myofibroblastic tumour''
 
     - [[Intranodal palisaded myofibroblastoma]]
 
     - [[Intranodal palisaded myofibroblastoma]]
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===Spleen-specific vascular-stromal tumours===
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'''Spleen-specific vascular-stromal tumours'''
 
   ''Splenic vascular-stromal tumours''
 
   ''Splenic vascular-stromal tumours''
 
     - [[Littoral cell angioma]]
 
     - [[Littoral cell angioma]]
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