Difference between revisions of "Testingnew move2"
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− | == | + | ==Forewords and Introductions[[chapter['chapterTitle'|Overview Page Link]]== |
- [[General Introduction]] | - [[General Introduction]] | ||
- [[ICCR datasets: Haemopoietic]] | - [[ICCR datasets: Haemopoietic]] | ||
− | == | + | ==Myeloid proliferations and neoplasms[[chapter['chapterTitle'|Overview Page Link]]== |
− | * | + | *Myeloid precursor lesions |
− | '' | + | ''Clonal Haematopoiesis'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Clonal haematopoiesis]] | - [[Clonal haematopoiesis]] | ||
- [[Clonal cytopenias of undetermined significance]] | - [[Clonal cytopenias of undetermined significance]] | ||
− | * | + | *Myeloproliferative neoplasms |
− | '' | + | ''Myeloproliferative neoplasms'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Chronic myeloid leukaemia]] | - [[Chronic myeloid leukaemia]] | ||
Line 19: | Line 19: | ||
- [[Juvenile myelomonocytic leukaemia]] | - [[Juvenile myelomonocytic leukaemia]] | ||
- [[Myeloproliferative neoplasm, NOS]] | - [[Myeloproliferative neoplasm, NOS]] | ||
− | * | + | *Mastocytosis |
- [[Introduction]] | - [[Introduction]] | ||
- [[Cutaneous mastocytosis]] | - [[Cutaneous mastocytosis]] | ||
- [[Systemic mastocytosis]] | - [[Systemic mastocytosis]] | ||
- [[Mast cell sarcoma]] | - [[Mast cell sarcoma]] | ||
− | * | + | *Myelodysplastic neoplasms |
- [[Introduction]] | - [[Introduction]] | ||
− | '' | + | ''Myelodysplastic neoplasms, with defining genetic abnormalities'' |
- [[Myelodysplastic neoplasm with low blasts and 5q deletion]] | - [[Myelodysplastic neoplasm with low blasts and 5q deletion]] | ||
- [[Myelodysplastic neoplasm with low blasts and SF3B1 mutation]] | - [[Myelodysplastic neoplasm with low blasts and SF3B1 mutation]] | ||
- [[Myelodysplastic neoplasm with biallelic TP53 inactivation]] | - [[Myelodysplastic neoplasm with biallelic TP53 inactivation]] | ||
− | '' | + | ''Myelodysplastic neoplasms, morphologically defined'' |
- [[Myelodysplastic neoplasm with low blasts]] | - [[Myelodysplastic neoplasm with low blasts]] | ||
- [[Myelodysplastic neoplasm, hypoplastic]] | - [[Myelodysplastic neoplasm, hypoplastic]] | ||
- [[Myelodysplastic neoplasm with increased blasts]] | - [[Myelodysplastic neoplasm with increased blasts]] | ||
− | '' | + | ''Myelodysplastic neoplasms of childhood'' |
- [[Childhood myelodysplastic neoplasm with low blasts]] | - [[Childhood myelodysplastic neoplasm with low blasts]] | ||
- [[Childhood myelodysplastic neoplasm with increased blasts]] | - [[Childhood myelodysplastic neoplasm with increased blasts]] | ||
− | * | + | *Myelodysplastic/myeloproliferative neoplasms |
- [[Introduction]] | - [[Introduction]] | ||
- [[Chronic myelomonocytic leukaemia]] | - [[Chronic myelomonocytic leukaemia]] | ||
Line 43: | Line 43: | ||
- [[Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis]] | - [[Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis]] | ||
- [[Myelodysplastic/myeloproliferative neoplasm, NOS]] | - [[Myelodysplastic/myeloproliferative neoplasm, NOS]] | ||
− | * | + | *Acute myeloid leukaemia |
- [[Introduction]] | - [[Introduction]] | ||
− | '' | + | ''Acute myeloid leukaemia with defining genetic abnormalities'' |
- [[Acute promyelocytic leukaemia with PML::RARA fusion]] | - [[Acute promyelocytic leukaemia with PML::RARA fusion]] | ||
- [[Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion]] | - [[Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion]] | ||
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- [[Acute myeloid leukaemia, myelodysplasia-related]] | - [[Acute myeloid leukaemia, myelodysplasia-related]] | ||
- [[Acute myeloid leukaemia with other defined genetic alterations]] | - [[Acute myeloid leukaemia with other defined genetic alterations]] | ||
− | '' | + | ''Acute myeloid leukaemia, defined by differentiation'' |
- [[Acute myeloid leukaemia with minimal differentiation]] | - [[Acute myeloid leukaemia with minimal differentiation]] | ||
- [[Acute myeloid leukaemia without maturation]] | - [[Acute myeloid leukaemia without maturation]] | ||
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- [[Acute erythroid leukaemia]] | - [[Acute erythroid leukaemia]] | ||
- [[Acute megakaryoblastic leukaemia]] | - [[Acute megakaryoblastic leukaemia]] | ||
− | '' | + | ''Myeloid sarcoma'' |
- [[Myeloid sarcoma]] | - [[Myeloid sarcoma]] | ||
− | * | + | *Myeloid neoplasms, secondary |
− | '' | + | ''Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Myeloid neoplasm post cytotoxic therapy]] | - [[Myeloid neoplasm post cytotoxic therapy]] | ||
- [[Myeloid neoplasms associated with germline predisposition]] | - [[Myeloid neoplasms associated with germline predisposition]] | ||
- [[Myeloid proliferations associated with Down syndrome]] | - [[Myeloid proliferations associated with Down syndrome]] | ||
− | * | + | *Myeloid/lymphoid neoplasms |
− | '' | + | ''Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Myeloid/lymphoid neoplasm with PDGFRA rearrangement]] | - [[Myeloid/lymphoid neoplasm with PDGFRA rearrangement]] | ||
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- [[Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion]] | - [[Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion]] | ||
- [[Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes]] | - [[Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes]] | ||
− | * | + | *Acute leukaemias of mixed or ambiguous lineage |
- [[Introduction]] | - [[Introduction]] | ||
− | '' | + | ''Acute leukaemia of ambiguous lineage with defining genetic abnormalities'' |
- [[Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]] | - [[Mixed-phenotype acute leukaemia with BCR::ABL1 fusion]] | ||
- [[Mixed-phenotype acute leukaemia with KMT2A rearrangement]] | - [[Mixed-phenotype acute leukaemia with KMT2A rearrangement]] | ||
- [[Acute leukaemia of ambiguous lineage with other defined genetic alterations ]] | - [[Acute leukaemia of ambiguous lineage with other defined genetic alterations ]] | ||
− | '' | + | ''Acute leukaemia of ambiguous lineage, immunophenotypically defined'' |
- [[Mixed-phenotype acute leukaemia, B/myeloid]] | - [[Mixed-phenotype acute leukaemia, B/myeloid]] | ||
- [[Mixed-phenotype acute leukaemia, T/myeloid]] | - [[Mixed-phenotype acute leukaemia, T/myeloid]] | ||
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- [[Acute leukaemia of ambiguous lineage, NOS]] | - [[Acute leukaemia of ambiguous lineage, NOS]] | ||
- [[Acute undifferentiated leukaemia]] | - [[Acute undifferentiated leukaemia]] | ||
− | == | + | ==Histiocytic/Dendritic cell neoplasms[[chapter['chapterTitle'|Overview Page Link]]== |
- [[Introduction]] | - [[Introduction]] | ||
− | * | + | *Plasmacytoid dendritic cell neoplasms |
− | '' | + | ''Plasmacytoid dendritic cell neoplasms'' |
- [[Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm]] | - [[Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm]] | ||
- [[Blastic plasmacytoid dendritic cell neoplasm]] | - [[Blastic plasmacytoid dendritic cell neoplasm]] | ||
− | * | + | *Langerhans cell and other dendritic cell neoplasms |
− | '' | + | ''Langerhans cells neoplasms'' |
- [[Langerhans cell histiocytosis]] | - [[Langerhans cell histiocytosis]] | ||
- [[Langerhans cell sarcoma]] | - [[Langerhans cell sarcoma]] | ||
− | '' | + | ''Other dendritic cell neoplasms'' |
- [[Indeterminate dendritic cell tumour]] | - [[Indeterminate dendritic cell tumour]] | ||
- [[Interdigitating dendritic cell sarcoma]] | - [[Interdigitating dendritic cell sarcoma]] | ||
− | * | + | *Histiocyte/macrophage neoplasms |
− | '' | + | ''Histiocytic neoplasms'' |
- [[Juvenile xanthogranuloma]] | - [[Juvenile xanthogranuloma]] | ||
- [[Erdheim-Chester disease]] | - [[Erdheim-Chester disease]] | ||
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- [[ALK-positive histiocytosis]] | - [[ALK-positive histiocytosis]] | ||
- [[Histiocytic sarcoma]] | - [[Histiocytic sarcoma]] | ||
− | == | + | ==B-cell lymphoid proliferations and lymphomas[[chapter['chapterTitle'|Overview Page Link]]== |
- [[Introduction to B-cell lymphoproliferative disorders and neoplasms]] | - [[Introduction to B-cell lymphoproliferative disorders and neoplasms]] | ||
− | * | + | *Tumour like lesions with B-cell predominance |
- [[Introduction]] | - [[Introduction]] | ||
- [[Reactive B-cell rich lymphoid proliferations that can mimic lymphoma]] | - [[Reactive B-cell rich lymphoid proliferations that can mimic lymphoma]] | ||
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- [[Idiopathic multicentric Castleman disease]] | - [[Idiopathic multicentric Castleman disease]] | ||
- [[KSHV/HHV8-associated multicentric Castleman disease]] | - [[KSHV/HHV8-associated multicentric Castleman disease]] | ||
− | * | + | *Precursor B-cell neoplasms |
− | '' | + | ''B-lymphoblastic leukaemias/lymphomas'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[B-lymphoblastic leukaemia/lymphoma]] | - [[B-lymphoblastic leukaemia/lymphoma]] | ||
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- [[B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations]] | - [[B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations]] | ||
- [[B-lymphoblastic leukaemia/lymphoma, NOS]] | - [[B-lymphoblastic leukaemia/lymphoma, NOS]] | ||
− | * | + | *Mature B-cell neoplasms |
− | '' | + | ''Pre-neoplastic and neoplastic small lymphocytic proliferations '' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Monoclonal B-cell lymphocytosis]] | - [[Monoclonal B-cell lymphocytosis]] | ||
- [[Chronic lymphocytic leukaemia/small lymphocytic lymphoma]] | - [[Chronic lymphocytic leukaemia/small lymphocytic lymphoma]] | ||
− | '' | + | ''Splenic B-cell lymphomas and leukaemias'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Hairy cell leukaemia]] | - [[Hairy cell leukaemia]] | ||
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- [[Splenic diffuse red pulp small B-cell lymphoma]] | - [[Splenic diffuse red pulp small B-cell lymphoma]] | ||
- [[Splenic B-cell lymphoma/leukaemia with prominent nucleoli]] | - [[Splenic B-cell lymphoma/leukaemia with prominent nucleoli]] | ||
− | '' | + | ''Lymphoplasmacytic lymphoma'' |
- [[Lymphoplasmacytic lymphoma]] | - [[Lymphoplasmacytic lymphoma]] | ||
− | '' | + | ''Marginal zone lymphoma'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue]] | - [[Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue]] | ||
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- [[Nodal marginal zone lymphoma]] | - [[Nodal marginal zone lymphoma]] | ||
- [[Paediatric nodal marginal zone lymphoma]] | - [[Paediatric nodal marginal zone lymphoma]] | ||
− | '' | + | ''Follicular lymphoma'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[In situ follicular B-cell neoplasm]] | - [[In situ follicular B-cell neoplasm]] | ||
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- [[Paediatric-type follicular lymphoma]] | - [[Paediatric-type follicular lymphoma]] | ||
- [[Duodenal-type follicular lymphoma]] | - [[Duodenal-type follicular lymphoma]] | ||
− | '' | + | ''Cutaneous follicle centre lymphoma'' |
- [[Primary cutaneous follicle centre lymphoma]] | - [[Primary cutaneous follicle centre lymphoma]] | ||
− | '' | + | ''Mantle cell lymphoma'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[In situ mantle cell neoplasm]] | - [[In situ mantle cell neoplasm]] | ||
- [[Mantle cell lymphoma]] | - [[Mantle cell lymphoma]] | ||
- [[Leukaemic non-nodal mantle cell lymphoma]] | - [[Leukaemic non-nodal mantle cell lymphoma]] | ||
− | '' | + | ''Transformations of indolent B-cell lymphomas'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Transformations of indolent B-cell lymphomas]] | - [[Transformations of indolent B-cell lymphomas]] | ||
− | '' | + | ''Large B-cell lymphomas'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Diffuse large B-cell lymphoma, NOS]] | - [[Diffuse large B-cell lymphoma, NOS]] | ||
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- [[Mediastinal grey zone lymphoma]] | - [[Mediastinal grey zone lymphoma]] | ||
- [[High-grade B-cell lymphoma, NOS]] | - [[High-grade B-cell lymphoma, NOS]] | ||
− | '' | + | ''Burkitt lymphoma'' |
- [[Burkitt lymphoma]] | - [[Burkitt lymphoma]] | ||
− | '' | + | ''KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Primary effusion lymphoma]] | - [[Primary effusion lymphoma]] | ||
- [[KSHV/HHV8-positive diffuse large B-cell lymphoma]] | - [[KSHV/HHV8-positive diffuse large B-cell lymphoma]] | ||
- [[KSHV/HHV8-positive germinotropic lymphoproliferative disorder]] | - [[KSHV/HHV8-positive germinotropic lymphoproliferative disorder]] | ||
− | '' | + | ''Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Hyperplasias arising in immune deficiency/dysregulation]] | - [[Hyperplasias arising in immune deficiency/dysregulation]] | ||
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- [[Lymphomas arising in immune deficiency / dysregulation ]] | - [[Lymphomas arising in immune deficiency / dysregulation ]] | ||
- [[Inborn error of immunity-associated lymphoid proliferations and lymphomas]] | - [[Inborn error of immunity-associated lymphoid proliferations and lymphomas]] | ||
− | * | + | *Hodgkin lymphoma |
- [[Introduction]] | - [[Introduction]] | ||
- [[Classic Hodgkin lymphoma ]] | - [[Classic Hodgkin lymphoma ]] | ||
- [[Nodular lymphocyte predominant Hodgkin lymphoma]] | - [[Nodular lymphocyte predominant Hodgkin lymphoma]] | ||
− | * | + | *Plasma cell neoplasms and other diseases with paraproteins |
- [[Introduction]] | - [[Introduction]] | ||
− | '' | + | ''Monoclonal gammopathies'' |
- [[Cold agglutinin disease ]] | - [[Cold agglutinin disease ]] | ||
- [[IgM monoclonal gammopathy of undetermined significance]] | - [[IgM monoclonal gammopathy of undetermined significance]] | ||
- [[Non-IgM monoclonal gammopathy of undetermined significance]] | - [[Non-IgM monoclonal gammopathy of undetermined significance]] | ||
- [[Monoclonal gammopathy of renal significance]] | - [[Monoclonal gammopathy of renal significance]] | ||
− | '' | + | ''Diseases with monoclonal immunoglobulin deposition'' |
- [[Immunoglobulin-related (AL) amyloidosis]] | - [[Immunoglobulin-related (AL) amyloidosis]] | ||
- [[Monoclonal immunoglobulin deposition disease]] | - [[Monoclonal immunoglobulin deposition disease]] | ||
− | '' | + | ''Heavy chain diseases'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Mu heavy chain disease]] | - [[Mu heavy chain disease]] | ||
- [[Gamma heavy chain disease]] | - [[Gamma heavy chain disease]] | ||
- [[Alpha heavy chain disease]] | - [[Alpha heavy chain disease]] | ||
− | '' | + | ''Plasma cell neoplasms'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Plasmacytoma]] | - [[Plasmacytoma]] | ||
- [[Plasma cell myeloma / multiple myeloma]] | - [[Plasma cell myeloma / multiple myeloma]] | ||
- [[Plasma cell neoplasms with associated paraneoplastic syndrome]] | - [[Plasma cell neoplasms with associated paraneoplastic syndrome]] | ||
− | == | + | ==T-cell and NK-cell lymphoid proliferations and lymphomas [[chapter['chapterTitle'|Overview Page Link]]== |
- [[Introduction]] | - [[Introduction]] | ||
− | * | + | *Tumour-like lesions with T-cell predominance |
- [[Kikuchi-Fujimoto disease]] | - [[Kikuchi-Fujimoto disease]] | ||
- [[Autoimmune lymphoproliferative syndrome]] | - [[Autoimmune lymphoproliferative syndrome]] | ||
- [[Indolent T-lymphoblastic proliferation]] | - [[Indolent T-lymphoblastic proliferation]] | ||
− | * | + | *Precursor T-cell neoplasms |
− | '' | + | ''T-lymphoblastic leukaemia / lymphoma'' |
- [[T-lymphoblastic leukaemia / lymphoma, NOS]] | - [[T-lymphoblastic leukaemia / lymphoma, NOS]] | ||
- [[Early T-precursor lymphoblastic leukaemia / lymphoma ]] | - [[Early T-precursor lymphoblastic leukaemia / lymphoma ]] | ||
− | * | + | *Mature T-cell and NK-cell neoplasms |
− | '' | + | ''Mature T-cell and NK-cell leukaemias'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[T-prolymphocytic leukaemia]] | - [[T-prolymphocytic leukaemia]] | ||
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- [[Sezary syndrome]] | - [[Sezary syndrome]] | ||
- [[Aggressive NK-cell leukaemia]] | - [[Aggressive NK-cell leukaemia]] | ||
− | '' | + | ''Primary cutaneous T-cell lymphoid proliferations and lymphomas'' |
- [[Introduction to primary cutaneous T-cell neoplasms]] | - [[Introduction to primary cutaneous T-cell neoplasms]] | ||
- [[Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder]] | - [[Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder]] | ||
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- [[Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma]] | - [[Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma]] | ||
- [[Primary cutaneous peripheral T-cell lymphoma, NOS]] | - [[Primary cutaneous peripheral T-cell lymphoma, NOS]] | ||
− | '' | + | ''Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Indolent T-cell lymphoma of the gastrointestinal tract]] | - [[Indolent T-cell lymphoma of the gastrointestinal tract]] | ||
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- [[Monomorphic epitheliotropic intestinal T-cell lymphoma]] | - [[Monomorphic epitheliotropic intestinal T-cell lymphoma]] | ||
- [[Intestinal T-cell lymphoma, NOS]] | - [[Intestinal T-cell lymphoma, NOS]] | ||
− | '' | + | ''Hepatosplenic T-cell lymphoma'' |
- [[Hepatosplenic T-cell lymphoma]] | - [[Hepatosplenic T-cell lymphoma]] | ||
− | '' | + | ''Anaplastic large cell lymphoma'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[ALK-positive anaplastic large cell lymphoma]] | - [[ALK-positive anaplastic large cell lymphoma]] | ||
- [[ALK-negative anaplastic large cell lymphoma]] | - [[ALK-negative anaplastic large cell lymphoma]] | ||
- [[Breast implant-associated anaplastic large cell lymphoma]] | - [[Breast implant-associated anaplastic large cell lymphoma]] | ||
− | '' | + | ''Nodal T-follicular helper (TFH) cell lymphoma'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Nodal TFH cell lymphoma, angioimmunoblastic-type]] | - [[Nodal TFH cell lymphoma, angioimmunoblastic-type]] | ||
- [[Nodal TFH cell lymphoma, follicular-type]] | - [[Nodal TFH cell lymphoma, follicular-type]] | ||
- [[Nodal TFH cell lymphoma, NOS]] | - [[Nodal TFH cell lymphoma, NOS]] | ||
− | '' | + | ''Other peripheral T-cell lymphomas'' |
- [[Peripheral T-cell lymphoma, NOS]] | - [[Peripheral T-cell lymphoma, NOS]] | ||
− | '' | + | ''EBV-positive NK-cell and T-cell lymphomas'' |
- [[EBV-positive nodal T- and NK-cell lymphoma]] | - [[EBV-positive nodal T- and NK-cell lymphoma]] | ||
- [[Extranodal NK/T-cell lymphoma]] | - [[Extranodal NK/T-cell lymphoma]] | ||
− | '' | + | ''EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood'' |
- [[Introduction]] | - [[Introduction]] | ||
- [[Severe mosquito bite allergy]] | - [[Severe mosquito bite allergy]] | ||
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- [[Systemic chronic active EBV disease]] | - [[Systemic chronic active EBV disease]] | ||
- [[Systemic EBV-positive T-cell lymphoma of childhood]] | - [[Systemic EBV-positive T-cell lymphoma of childhood]] | ||
− | == | + | ==Stroma-derived neoplasms of lymphoid tissues[[chapter['chapterTitle'|Overview Page Link]]== |
- [[Introduction]] | - [[Introduction]] | ||
− | * | + | *Mesenchymal dendritic cell neoplasms |
− | '' | + | ''Follicular dendritic cell neoplasms'' |
- [[Follicular dendritic cell sarcoma]] | - [[Follicular dendritic cell sarcoma]] | ||
- [[EBV-positive inflammatory follicular dendritic cell sarcoma]] | - [[EBV-positive inflammatory follicular dendritic cell sarcoma]] | ||
- [[Fibroblastic reticular cell tumour]] | - [[Fibroblastic reticular cell tumour]] | ||
− | * | + | *Myofibroblastic tumours |
− | '' | + | ''Myofibroblastic tumour'' |
- [[Intranodal palisaded myofibroblastoma]] | - [[Intranodal palisaded myofibroblastoma]] | ||
− | * | + | *Spleen-specific vascular-stromal tumours |
− | '' | + | ''Splenic vascular-stromal tumours'' |
- [[Littoral cell angioma]] | - [[Littoral cell angioma]] | ||
- [[Splenic hamartoma]] | - [[Splenic hamartoma]] | ||
- [[Sclerosing angiomatoid nodular transformation (SANT) of spleen]] | - [[Sclerosing angiomatoid nodular transformation (SANT) of spleen]] | ||
− | == | + | ==Genetic tumour syndromes[[chapter['chapterTitle'|Overview Page Link]]== |
- [[Introduction]] | - [[Introduction]] | ||
- [[Fanconi anaemia]] | - [[Fanconi anaemia]] |
Revision as of 11:37, 25 August 2022
Forewords and Introductions[[chapter['chapterTitle'|Overview Page Link]]
- General Introduction - ICCR datasets: Haemopoietic
Myeloid proliferations and neoplasms[[chapter['chapterTitle'|Overview Page Link]]
- Myeloid precursor lesions
Clonal Haematopoiesis - Introduction - Clonal haematopoiesis - Clonal cytopenias of undetermined significance
- Myeloproliferative neoplasms
Myeloproliferative neoplasms - Introduction - Chronic myeloid leukaemia - Chronic neutrophilic leukaemia - Chronic eosinophilic leukaemia - Polycythaemia vera - Essential thrombocythaemia - Primary myelofibrosis - Juvenile myelomonocytic leukaemia - Myeloproliferative neoplasm, NOS
- Mastocytosis
- Introduction - Cutaneous mastocytosis - Systemic mastocytosis - Mast cell sarcoma
- Myelodysplastic neoplasms
- Introduction Myelodysplastic neoplasms, with defining genetic abnormalities - Myelodysplastic neoplasm with low blasts and 5q deletion - Myelodysplastic neoplasm with low blasts and SF3B1 mutation - Myelodysplastic neoplasm with biallelic TP53 inactivation Myelodysplastic neoplasms, morphologically defined - Myelodysplastic neoplasm with low blasts - Myelodysplastic neoplasm, hypoplastic - Myelodysplastic neoplasm with increased blasts Myelodysplastic neoplasms of childhood - Childhood myelodysplastic neoplasm with low blasts - Childhood myelodysplastic neoplasm with increased blasts
- Myelodysplastic/myeloproliferative neoplasms
- Introduction - Chronic myelomonocytic leukaemia - Myelodysplastic/myeloproliferative neoplasm with neutrophilia - Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis - Myelodysplastic/myeloproliferative neoplasm, NOS
- Acute myeloid leukaemia
- Introduction Acute myeloid leukaemia with defining genetic abnormalities - Acute promyelocytic leukaemia with PML::RARA fusion - Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion - Acute myeloid leukaemia with CBFB::MYH11 fusion - Acute myeloid leukaemia with DEK::NUP214 fusion - Acute myeloid leukaemia with RBM15::MRTFA fusion - Acute myeloid leukaemia with BCR::ABL1 fusion - Acute myeloid leukaemia with KMT2A rearrangement - Acute myeloid leukaemia with MECOM rearrangement - Acute myeloid leukaemia with NUP98 rearrangement - Acute myeloid leukaemia with NPM1 mutation - Acute myeloid leukaemia with CEBPA mutation - Acute myeloid leukaemia, myelodysplasia-related - Acute myeloid leukaemia with other defined genetic alterations Acute myeloid leukaemia, defined by differentiation - Acute myeloid leukaemia with minimal differentiation - Acute myeloid leukaemia without maturation - Acute myeloid leukaemia with maturation - Acute basophilic leukaemia - Acute myelomonocytic leukaemia - Acute monocytic leukaemia - Acute erythroid leukaemia - Acute megakaryoblastic leukaemia Myeloid sarcoma - Myeloid sarcoma
- Myeloid neoplasms, secondary
Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions - Introduction - Myeloid neoplasm post cytotoxic therapy - Myeloid neoplasms associated with germline predisposition - Myeloid proliferations associated with Down syndrome
- Myeloid/lymphoid neoplasms
Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement - Introduction - Myeloid/lymphoid neoplasm with PDGFRA rearrangement - Myeloid/lymphoid neoplasm with PDGFRB rearrangement - Myeloid/lymphoid neoplasm with FGFR1 rearrangement - Myeloid/lymphoid neoplasm with JAK2 rearrangement - Myeloid/lymphoid neoplasm with FLT3 rearrangement - Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion - Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes
- Acute leukaemias of mixed or ambiguous lineage
- Introduction Acute leukaemia of ambiguous lineage with defining genetic abnormalities - Mixed-phenotype acute leukaemia with BCR::ABL1 fusion - Mixed-phenotype acute leukaemia with KMT2A rearrangement - Acute leukaemia of ambiguous lineage with other defined genetic alterations Acute leukaemia of ambiguous lineage, immunophenotypically defined - Mixed-phenotype acute leukaemia, B/myeloid - Mixed-phenotype acute leukaemia, T/myeloid - Mixed-phenotype acute leukaemia, rare types - Acute leukaemia of ambiguous lineage, NOS - Acute undifferentiated leukaemia
Histiocytic/Dendritic cell neoplasms[[chapter['chapterTitle'|Overview Page Link]]
- Introduction
- Plasmacytoid dendritic cell neoplasms
Plasmacytoid dendritic cell neoplasms - Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm - Blastic plasmacytoid dendritic cell neoplasm
- Langerhans cell and other dendritic cell neoplasms
Langerhans cells neoplasms - Langerhans cell histiocytosis - Langerhans cell sarcoma Other dendritic cell neoplasms - Indeterminate dendritic cell tumour - Interdigitating dendritic cell sarcoma
- Histiocyte/macrophage neoplasms
Histiocytic neoplasms - Juvenile xanthogranuloma - Erdheim-Chester disease - Rosai-Dorfman Disease - ALK-positive histiocytosis - Histiocytic sarcoma
B-cell lymphoid proliferations and lymphomas[[chapter['chapterTitle'|Overview Page Link]]
- Introduction to B-cell lymphoproliferative disorders and neoplasms
- Tumour like lesions with B-cell predominance
- Introduction - Reactive B-cell rich lymphoid proliferations that can mimic lymphoma - IgG4-related disease - Unicentric Castleman disease - Idiopathic multicentric Castleman disease - KSHV/HHV8-associated multicentric Castleman disease
- Precursor B-cell neoplasms
B-lymphoblastic leukaemias/lymphomas - Introduction - B-lymphoblastic leukaemia/lymphoma - B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy - B-lymphoblastic leukaemia/lymphoma with hypodiploidy - B-lymphoblastic leukaemia/lymphoma with iAMP21 - B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion - B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features - B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement - B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion - B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features - B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion - B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion - B lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion - B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations - B-lymphoblastic leukaemia/lymphoma, NOS
- Mature B-cell neoplasms
Pre-neoplastic and neoplastic small lymphocytic proliferations - Introduction - Monoclonal B-cell lymphocytosis - Chronic lymphocytic leukaemia/small lymphocytic lymphoma Splenic B-cell lymphomas and leukaemias - Introduction - Hairy cell leukaemia - Splenic marginal zone lymphoma - Splenic diffuse red pulp small B-cell lymphoma - Splenic B-cell lymphoma/leukaemia with prominent nucleoli Lymphoplasmacytic lymphoma - Lymphoplasmacytic lymphoma Marginal zone lymphoma - Introduction - Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue - Primary cutaneous marginal zone lymphoma - Nodal marginal zone lymphoma - Paediatric nodal marginal zone lymphoma Follicular lymphoma - Introduction - In situ follicular B-cell neoplasm - Follicular lymphoma - Paediatric-type follicular lymphoma - Duodenal-type follicular lymphoma Cutaneous follicle centre lymphoma - Primary cutaneous follicle centre lymphoma Mantle cell lymphoma - Introduction - In situ mantle cell neoplasm - Mantle cell lymphoma - Leukaemic non-nodal mantle cell lymphoma Transformations of indolent B-cell lymphomas - Introduction - Transformations of indolent B-cell lymphomas Large B-cell lymphomas - Introduction - Diffuse large B-cell lymphoma, NOS - T-cell/histiocyte-rich large B-cell lymphoma - Diffuse large B-cell lymphoma / high grade B-cell lymphoma with MYC and BCL2 rearrangements - ALK-positive large B-cell lymphoma - Large B-cell lymphoma with IRF4 rearrangement - High grade B-cell lymphoma with 11q aberrations - Lymphomatoid granulomatosis - EBV-positive diffuse large B-cell lymphoma - Diffuse large B-cell lymphoma associated with chronic inflammation - Fibrin-associated large B-cell lymphoma - Fluid overload-associated large B-cell lymphoma - Plasmablastic lymphoma - Primary large B-cell lymphoma of immune-privileged sites - Primary cutaneous diffuse large B-cell lymphoma, leg type - Intravascular large B-cell lymphoma - Primary mediastinal large B-cell lymphoma - Mediastinal grey zone lymphoma - High-grade B-cell lymphoma, NOS Burkitt lymphoma - Burkitt lymphoma KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas - Introduction - Primary effusion lymphoma - KSHV/HHV8-positive diffuse large B-cell lymphoma - KSHV/HHV8-positive germinotropic lymphoproliferative disorder Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation - Introduction - Hyperplasias arising in immune deficiency/dysregulation - Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation - EBV-positive mucocutaneous ulcer - Lymphomas arising in immune deficiency / dysregulation - Inborn error of immunity-associated lymphoid proliferations and lymphomas
- Hodgkin lymphoma
- Introduction - Classic Hodgkin lymphoma - Nodular lymphocyte predominant Hodgkin lymphoma
- Plasma cell neoplasms and other diseases with paraproteins
- Introduction Monoclonal gammopathies - Cold agglutinin disease - IgM monoclonal gammopathy of undetermined significance - Non-IgM monoclonal gammopathy of undetermined significance - Monoclonal gammopathy of renal significance Diseases with monoclonal immunoglobulin deposition - Immunoglobulin-related (AL) amyloidosis - Monoclonal immunoglobulin deposition disease Heavy chain diseases - Introduction - Mu heavy chain disease - Gamma heavy chain disease - Alpha heavy chain disease Plasma cell neoplasms - Introduction - Plasmacytoma - Plasma cell myeloma / multiple myeloma - Plasma cell neoplasms with associated paraneoplastic syndrome
T-cell and NK-cell lymphoid proliferations and lymphomas [[chapter['chapterTitle'|Overview Page Link]]
- Introduction
- Tumour-like lesions with T-cell predominance
- Kikuchi-Fujimoto disease - Autoimmune lymphoproliferative syndrome - Indolent T-lymphoblastic proliferation
- Precursor T-cell neoplasms
T-lymphoblastic leukaemia / lymphoma - T-lymphoblastic leukaemia / lymphoma, NOS - Early T-precursor lymphoblastic leukaemia / lymphoma
- Mature T-cell and NK-cell neoplasms
Mature T-cell and NK-cell leukaemias - Introduction - T-prolymphocytic leukaemia - T-large granular lymphocytic leukaemia - NK-large granular lymphocytic leukaemia - Adult T-cell leukaemia/lymphoma - Sezary syndrome - Aggressive NK-cell leukaemia Primary cutaneous T-cell lymphoid proliferations and lymphomas - Introduction to primary cutaneous T-cell neoplasms - Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder - Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder - Mycosis fungoides - Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis - Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma - Subcutaneous panniculitis-like T-cell lymphoma - Primary cutaneous gamma/delta T-cell lymphoma - Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma - Primary cutaneous peripheral T-cell lymphoma, NOS Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas - Introduction - Indolent T-cell lymphoma of the gastrointestinal tract - Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract - Enteropathy-associated T-cell lymphoma - Monomorphic epitheliotropic intestinal T-cell lymphoma - Intestinal T-cell lymphoma, NOS Hepatosplenic T-cell lymphoma - Hepatosplenic T-cell lymphoma Anaplastic large cell lymphoma - Introduction - ALK-positive anaplastic large cell lymphoma - ALK-negative anaplastic large cell lymphoma - Breast implant-associated anaplastic large cell lymphoma Nodal T-follicular helper (TFH) cell lymphoma - Introduction - Nodal TFH cell lymphoma, angioimmunoblastic-type - Nodal TFH cell lymphoma, follicular-type - Nodal TFH cell lymphoma, NOS Other peripheral T-cell lymphomas - Peripheral T-cell lymphoma, NOS EBV-positive NK-cell and T-cell lymphomas - EBV-positive nodal T- and NK-cell lymphoma - Extranodal NK/T-cell lymphoma EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood - Introduction - Severe mosquito bite allergy - Hydroa vacciniforme lymphoproliferative disorder - Systemic chronic active EBV disease - Systemic EBV-positive T-cell lymphoma of childhood
Stroma-derived neoplasms of lymphoid tissues[[chapter['chapterTitle'|Overview Page Link]]
- Introduction
- Mesenchymal dendritic cell neoplasms
Follicular dendritic cell neoplasms - Follicular dendritic cell sarcoma - EBV-positive inflammatory follicular dendritic cell sarcoma - Fibroblastic reticular cell tumour
- Myofibroblastic tumours
Myofibroblastic tumour - Intranodal palisaded myofibroblastoma
- Spleen-specific vascular-stromal tumours
Splenic vascular-stromal tumours - Littoral cell angioma - Splenic hamartoma - Sclerosing angiomatoid nodular transformation (SANT) of spleen
Genetic tumour syndromes[[chapter['chapterTitle'|Overview Page Link]]
- Introduction - Fanconi anaemia - Bloom syndrome - Ataxia-telangiectasia syndrome - RASopathies