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The ''TP53'' gene is well-known tumor suppressor gene that has been implicated in many cancer types [1]. The ''TP53'' protein product is involved in regulating the cell cycle pathway and can prevent replication if cell damage has occurred [2]. Deletions, LOH, and loss of function (LOF) mutations have been associated with ''TP53''. These alterations often confer a poor prognosis and chemoresistance.

The ''TP53'' gene is well-known tumor suppressor gene that has been implicated in many cancer types [1]. The ''TP53'' protein product is involved in regulating the cell cycle pathway and can prevent replication if cell damage has occurred [2]. Deletions, LOH, and loss of function (LOF) mutations have been associated with ''TP53''. These alterations often confer a poor prognosis and chemoresistance.

==Most Common Types of Alterations==

==Common Alteration Types==

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