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==References==
 
==References==
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=== EXAMPLE Book ===
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*Asmar, F., Christensen, J., Johansen, J.V., Blåbjerg, A., Pedersen, A., Hother, C., Ralfkiaer, U., Helin, K., and Grønbæk, K. (2011). TET2 mutations in Diffuse Large B-Cell Lymphoma: The Role of TET2 in the Regulation of Methylation Patterns at TET2 Target Genes. Blood 118, 1364–1364. PMID:
#Arber DA, et al., (2008). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, Editors. IARC Press: Lyon, France, p117-118.
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=== EXAMPLE Journal Article ===
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*Bejar, R., Stevenson, K., Abdel-Wahab, O., Galili, N., Nilsson, B., Garcia-Manero, G., Kantarjian, H., Raza, A., Levine, R.L., Neuberg, D., et al. (2011). Clinical effect of point mutations in myelodysplastic syndromes. N. Engl. J. Med. 364, 2496–2506. PMID: 21714648
#Li Y, et al., (2001). Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet 28:220-221, PMID 11431691.
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*Busque, L., Patel, J.P., Figueroa, M., Vasanthakumar, A., Provost, S., Hamilou, Z., Mollica, L., Li, J., Viale, A., Heguy, A., et al. (2012). Recurrent Somatic TET2 Mutations in Normal Elderly Individuals With Clonal Hematopoiesis. Nat Genet 44, 1179–1181. PMID: 23001125
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*Chen, Q., Chen, Y., Bian, C., Fujiki, R., and Yu, X. (2013). TET2 promotes histone O-GlcNAcylation during gene transcription. Nature 493, 561–564. PMID: 23222540
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*Ciesielski, P., Jóźwiak, P., Wójcik-Krowiranda, K., Forma, E., Cwonda, Ł., Szczepaniec, S., Bieńkiewicz, A., Bryś, M., and Krześlak, A. (2017). Differential expression of ten-eleven translocation genes in endometrial cancers. Tumour Biol. 39, 1010428317695017. PMID: 28349832
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*Cimmino, L., Abdel-Wahab, O., Levine, R.L., and Aifantis, I. (2011). TET family proteins and their role in stem cell differentiation and transformation. Cell Stem Cell 9, 193–204. PMID: 21885017
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*Delhommeau, F., Dupont, S., Della Valle, V., James, C., Trannoy, S., Massé, A., Kosmider, O., Le Couedic, J.-P., Robert, F., Alberdi, A., et al. (2009). Mutation in TET2 in myeloid cancers. N. Engl. J. Med. 360, 2289–2301. PMID: 19474426
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*Deng, W., Wang, J., Zhang, J., Cai, J., Bai, Z., and Zhang, Z. (2016). TET2 regulates LncRNA-ANRIL expression and inhibits the growth of human gastric cancer cells. IUBMB Life 68, 355–364. PMID: 27027260
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*Deplus, R., Delatte, B., Schwinn, M.K., Defrance, M., Méndez, J., Murphy, N., Dawson, M.A., Volkmar, M., Putmans, P., Calonne, E., et al. (2013). TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. The EMBO Journal 32, 645–655. PMID: 23353889
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*Du, C., Kurabe, N., Matsushima, Y., Suzuki, M., Kahyo, T., Ohnishi, I., Tanioka, F., Tajima, S., Goto, M., Yamada, H., et al. (2015). Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer. Gastric Cancer 18, 516–525. PMID: 25098926
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*Figueroa, M.E., Abdel-Wahab, O., Lu, C., Ward, P.S., Patel, J., Shih, A., Li, Y., Bhagwat, N., Vasanthakumar, A., Fernandez, H.F., et al. (2010). Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18, 553–567. PMID: 21130701
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*Guo, X., Long, J., Zeng, C., Michailidou, K., Ghoussaini, M., Bolla, M.K., Wang, Q., Milne, R.L., Shu, X.-O., Cai, Q., et al. (2015). Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 24, 1680–1691. PMID: 26354892
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*Huang, Y., Wang, G., Liang, Z., Yang, Y., Cui, L., and Liu, C.-Y. (2016). Loss of nuclear localization of TET2 in colorectal cancer. Clin Epigenetics 8, 9. PMID: 26816554
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*Itzykson, R., Kosmider, O., Cluzeau, T., Mansat-De Mas, V., Dreyfus, F., Beyne-Rauzy, O., Quesnel, B., Vey, N., Gelsi-Boyer, V., Raynaud, S., et al. (2011). Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias. Leukemia 25, 1147–1152. PMID: 21494260
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*Itzykson, R., Kosmider, O., Renneville, A., Morabito, M., Preudhomme, C., Berthon, C., Adès, L., Fenaux, P., Platzbecker, U., Gagey, O., et al. (2013a). Clonal architecture of chronic myelomonocytic leukemias. Blood 121, 2186–2198. PMID: 23319568
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*Itzykson, R., Kosmider, O., Renneville, A., Gelsi-Boyer, V., Meggendorfer, M., Morabito, M., Berthon, C., Adès, L., Fenaux, P., Beyne-Rauzy, O., et al. (2013b). Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia. Journal of Clinical Oncology 31, 2428–2436. PMID: 23690417
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*Kim, S.I., Lee, J.W., Lee, M., Kim, H.S., Chung, H.H., Kim, J.-W., Park, N.H., Song, Y.-S., and Seo, J.-S. (2018). Genomic landscape of ovarian clear cell carcinoma via whole exome sequencing. Gynecol. Oncol. 148, 375–382. PMID: 29233531
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*Kim, Y.-H., Pierscianek, D., Mittelbronn, M., Vital, A., Mariani, L., Hasselblatt, M., and Ohgaki, H. (2011). TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations. J. Clin. Pathol. 64, 850–852. PMID: 21690245
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*Ko, M., An, J., Bandukwala, H.S., Chavez, L., Aijö, T., Pastor, W.A., Segal, M.F., Li, H., Koh, K.P., Lähdesmäki, H., et al. (2013). Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature 497, 122–126. PMID: 23563267
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*Koutros, S., Berndt, S.I., Hughes Barry, K., Andreotti, G., Hoppin, J.A., Sandler, D.P., Yeager, M., Burdett, L.A., Yuenger, J., Alavanja, M.C.R., et al. (2013). Genetic Susceptibility Loci, Pesticide Exposure and Prostate Cancer Risk. PLoS One 8. PMID: 23593118
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*Kraus, T.F.J., Greiner, A., Steinmaurer, M., Dietinger, V., Guibourt, V., and Kretzschmar, H.A. (2015). Genetic Characterization of Ten-Eleven-Translocation Methylcytosine Dioxygenase Alterations in Human Glioma. J Cancer 6, 832–842. PMID: 26284134
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*Kunimoto, H., Fukuchi, Y., Sakurai, M., Sadahira, K., Ikeda, Y., Okamoto, S., and Nakajima, H. (2012). Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells. Sci Rep 2, 273. PMID: 22355785
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*Langemeijer, S.M.C., Kuiper, R.P., Berends, M., Knops, R., Aslanyan, M.G., Massop, M., Stevens-Linders, E., Hoogen, P. van, Kessel, A.G. van, Raymakers, R.A.P., et al. (2009). Acquired mutations in TET2 are common in myelodysplastic syndromes. Nature Genetics 41, 838–842. PMID: 19483684
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*Lemonnier, F., Couronné, L., Parrens, M., Jaïs, J.-P., Travert, M., Lamant, L., Tournillac, O., Rousset, T., Fabiani, B., Cairns, R.A., et al. (2012). Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters. Blood 120, 1466–1469. PMID: 22760778
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*Lorsbach, R.B., Moore, J., Mathew, S., Raimondi, S.C., Mukatira, S.T., and Downing, J.R. (2003). TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 17, 637–641. PMID: 12646957
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*Moran-Crusio, K., Reavie, L., Shih, A., Abdel-Wahab, O., Ndiaye-Lobry, D., Lobry, C., Figueroa, M.E., Vasanthakumar, A., Patel, J., Zhao, X., et al. (2011). Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation. Cancer Cell 20, 11–24. PMID: 21723200
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*Muto, T., Sashida, G., Oshima, M., Wendt, G.R., Mochizuki-Kashio, M., Nagata, Y., Sanada, M., Miyagi, S., Saraya, A., Kamio, A., et al. (2013). Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders. Journal of Experimental Medicine 210, 2627–2639. PMID: 24218139
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*Namba-Fukuyo, H., Funata, S., Matsusaka, K., Fukuyo, M., Rahmutulla, B., Mano, Y., Fukayama, M., Aburatani, H., and Kaneda, A. (2016). TET2 functions as a resistance factor against DNA methylation acquisition during Epstein-Barr virus infection. Oncotarget 7, 81512–81526. PMID: 27829228
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*Odejide, O., Weigert, O., Lane, A.A., Toscano, D., Lunning, M.A., Kopp, N., Kim, S., Bodegom, D. van, Bolla, S., Schatz, J.H., et al. (2014). A targeted mutational landscape of angioimmunoblastic T-cell lymphoma. Blood 123, 1293–1296. PMID: 24345752
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*Pan, F., Weeks, O., Yang, F.-C., and Xu, M. (2015). The TET2 interactors and their links to hematological malignancies. IUBMB Life 67, 438–445. PMID: 26099018
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*Patel, J.P., Gönen, M., Figueroa, M.E., Fernandez, H., Sun, Z., Racevskis, J., Van Vlierberghe, P., Dolgalev, I., Thomas, S., Aminova, O., et al. (2012). Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N. Engl. J. Med. 366, 1079–1089. PMID: 22417203
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*Patnaik, M.M., Lasho, T.L., Vijayvargiya, P., Finke, C.M., Hanson, C.A., Ketterling, R.P., Gangat, N., and Tefferi, A. (2016). Prognostic interaction between ASXL1 and TET2 mutations in chronic myelomonocytic leukemia. Blood Cancer J 6, e385. PMID: 26771811
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*Quivoron, C., Couronné, L., Della Valle, V., Lopez, C.K., Plo, I., Wagner-Ballon, O., Do Cruzeiro, M., Delhommeau, F., Arnulf, B., Stern, M.-H., et al. (2011). TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20, 25–38. PMID: 21723201
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*Rawłuszko-Wieczorek, A.A., Siera, A., Horbacka, K., Horst, N., Krokowicz, P., and Jagodziński, P.P. (2015). Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer. J. Cancer Res. Clin. Oncol. 141, 1379–1392. PMID: 25557833
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*Setiawan, V.W., Schumacher, F., Prescott, J., Haessler, J., Malinowski, J., Wentzensen, N., Yang, H., Chanock, S., Brinton, L., Hartge, P., et al. (2014). Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia. Carcinogenesis 35, 2068–2073. PMID: 24832084
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*Solary, E., Bernard, O.A., Tefferi, A., Fuks, F., and Vainchenker, W. (2014). The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases. Leukemia 28, 485–496. PMID: 24220273
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*Steensma, D.P., Bejar, R., Jaiswal, S., Lindsley, R.C., Sekeres, M.A., Hasserjian, R.P., and Ebert, B.L. (2015). Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood 126, 9–16. PMID: 25931582
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*Swerdlow, S.H., Campo, E., Harris, N.L., Pileri, S.A., Jaffe, E.S., Stein, H., and Thiele, J. (2017). WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (International Agency for Research on Cancer).
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*Takayama, K., Misawa, A., Suzuki, T., Takagi, K., Hayashizaki, Y., Fujimura, T., Homma, Y., Takahashi, S., Urano, T., and Inoue, S. (2015). TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression. Nat Commun 6, 8219. PMID: 26404510
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*Tsai, K.-W., Li, G.-C., Chen, C.-H., Yeh, M.-H., Huang, J.-S., Tseng, H.-H., Fu, T.-Y., Liou, H.-H., Pan, H.-W., Huang, S.-F., et al. (2015). Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype. Breast Cancer Res. Treat. 153, 219–234. PMID: 26253945
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*Vella, P., Scelfo, A., Jammula, S., Chiacchiera, F., Williams, K., Cuomo, A., Roberto, A., Christensen, J., Bonaldi, T., Helin, K., et al. (2013). Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells. Molecular Cell 49, 645–656. PMID: 23352454
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*Wang, Y., Xiao, M., Chen, X., Chen, L., Xu, Y., Lv, L., Wang, P., Yang, H., Ma, S., Lin, H., et al. (2015). WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation. Mol. Cell 57, 662–673. PMID: 25601757
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*Weissmann, S., Alpermann, T., Grossmann, V., Kowarsch, A., Nadarajah, N., Eder, C., Dicker, F., Fasan, A., Haferlach, C., Haferlach, T., et al. (2012). Landscape of TET2 mutations in acute myeloid leukemia. Leukemia 26, 934–942. PMID: 22116554
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*Wu, H., and Zhang, Y. (2014). Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions. Cell 156, 45–68. PMID: 24439369
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*Yan, H., Parsons, D.W., Jin, G., McLendon, R., Rasheed, B.A., Yuan, W., Kos, I., Batinic-Haberle, I., Jones, S., and Riggins, G.J. (2009). IDH1 and IDH2 mutations in gliomas. New England Journal of Medicine 360, 765–773. PMID: 23532369
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*Yang, L., Yu, S.-J., Hong, Q., Yang, Y., and Shao, Z.-M. (2015). Reduced Expression of TET1, TET2, TET3 and TDG mRNAs Are Associated with Poor Prognosis of Patients with Early Breast Cancer. PLoS ONE 10, e0133896. PMID: 26207381
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*Yang, Q., Wu, K., Ji, M., Jin, W., He, N., Shi, B., and Hou, P. (2013). Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients. J Biomed Nanotechnol 9, 1607–1616. PMID: 23980508
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*Zhang, L.-Y., Li, P.-L., Wang, T.-Z., and Zhang, X.-C. (2015). Prognostic values of 5-hmC, 5-mC and TET2 in epithelial ovarian cancer. Arch. Gynecol. Obstet. 292, 891–897. PMID: 25827305
    
== Notes ==
 
== Notes ==
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