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==Recurrent Genomic Alterations in Pediatric and Adult CNS Detected by Chromosomal Microarray (Literature Review)==
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==Recurrent Genomic Alterations in Pediatric and Adult CNS Detected by Chromosomal Microarray
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Table 1 - Pediatric Central Nervous System Tumors.  Table derived from Ligon et al., 2018 [  ] with permission from Cancer Genetics.
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Table 1 - Pediatric Central Nervous System Tumors.  Table derived from CGC CNS Workgroup 2018.
 
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| Generally indolent tumors for which  surgical resection can be curative  
 
| Generally indolent tumors for which  surgical resection can be curative  
 
| PMID:25461780; PMID:23583981; PMID:11996800 PMID:23609006; PMID:29880043
 
| PMID:25461780; PMID:23583981; PMID:11996800 PMID:23609006; PMID:29880043
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|-
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|Low grade glioma, WHO grade II
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|Diffuse astrocytoma
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|No diagnostic aberrations
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| '''Rearrangement:''' MYBL1 truncating rearrangements and tandem duplication, FGFR1 rearrangements; '''Mutation:''' FGFR1
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| Anaplastic features associated with decreased progression free survival
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| PMID:25664944; PMID:23633565; PMID:26061751 PMID:26824661; PMID:26004297; PMID:25461780  PMID:23583981
 
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| Pleomorphic xanthoastrocytoma (PXA)
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| Polysomy 3, polysomy 7 observed; '''Loss:''' monosomy 9 / 9p deletion
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| '''Mutations:''' BRAF V600E in ~60%; TP53 (5%); '''Loss:''' CDKN2A/CDKN2B
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|
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| PMID:25461780; PMID:23583981; PMID:16909113; PMID:12484572
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|-