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Renal Cell Neoplasia Tables: Recurrent Cytogenomic Alterations (view source)
Revision as of 22:47, 14 January 2021
, 22:47, 14 January 2021no edit summary
{{DISPLAYTITLE:Renal Table: Recurrent Genomic Alterations Detected by Chromosomal Microarray}}
'''Table 1 - Recurrent Genomic Alterations in AML Detected by Chromosomal Microarray (Literature Review)'''. This is a comprehensive list of CNAs and CN-LOH detectable by CMA testing with strong diagnostic, prognostic and treatment implications in AML. Table derived from Xu et al., 2018 [PMID: 32434132] with permission from Cancer Genetics.
{| class="wikitable"
{| class="wikitable"
| colspan="8" |'''WHO Classification'''
| colspan="8" |'''WHO Classification'''
|'''Papillary RCC'''
|'''Papillary RCC'''
'''Type 1'''
'''Type 1'''
|'''Papillary RCC'''
|'''Papillary RCC'''
|15-20%
|15-20%
|15-20%
|15-20%
| colspan="2" |1-5%
| colspan="2" | 1-5%
|5%
| 5%
|5%
| 5%
|-
|-
|'''Origin'''
|'''Origin'''
|1p- (10%) [2; R]
|1p- (10%) [2; R]
|
|
|1p- (25%) [2; R]
| 1p- (25%) [2; R]
| colspan="2" |1p- (30%) [3; R]
| colspan="2" |1p- (30%) [3; R]
|'''-1''' (90%) '''[1; D]<sup>c</sup>'''
|'''-1''' (90%) '''[1; D]<sup>c</sup>'''
|'''+7/+7,+7''' (84%) '''[1; D]<sup>c</sup>'''
|'''+7/+7,+7''' (84%) '''[1; D]<sup>c</sup>'''
|'''+7''' (25%) '''[1; D]'''
|'''+7''' (25%) '''[1; D]'''
| colspan="2" |+7 (30%) [3; R]
| colspan="2" | +7 (30%) [3; R]
|
|
|
|
|<nowiki>+12 (52%) [2; R]</nowiki>
|<nowiki>+12 (52%) [2; R]</nowiki>
|<nowiki>+12 (15%) [3; R]</nowiki>
|<nowiki>+12 (15%) [3; R]</nowiki>
| colspan="2" |+12 (35%) [3; R]
| colspan="2" | +12 (35%) [3; R]
|
|
|
|
|
|
|<nowiki>-15 (15%) [3; R]</nowiki>
|<nowiki>-15 (15%) [3; R]</nowiki>
| colspan="2" |-15 (15%) [3; R]
| colspan="2" | -15 (15%) [3; R]
|
|
|
|
| colspan="8" |'''Mutations (SNVs, Indels) [level of evidence; clinical significance]'''
| colspan="8" |'''Mutations (SNVs, Indels) [level of evidence; clinical significance]'''
|-
|-
|Mutated
| Mutated
in >20%
in >20%
|
|
|-
|-
|Mutated
| Mutated
in 10-20%
in 10-20%