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| Ganglioglioma
 
| Ganglioglioma
| Only 30% are abnormal by karyotype '''Gain:''' polysomy 7
+
| Only 30% are abnormal by karyotype <br>
 +
'''Gain:''' polysomy 7
 
| '''Mutations:''' BRAF V600E in 20-60% of cases (can be concurrent with CDKN2A homozygous deletion)<br>
 
| '''Mutations:''' BRAF V600E in 20-60% of cases (can be concurrent with CDKN2A homozygous deletion)<br>
 
'''Fusions:''' KIAA1549-BRAF
 
'''Fusions:''' KIAA1549-BRAF
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|
 
| Pleomorphic xanthoastrocytoma (PXA)
 
| Pleomorphic xanthoastrocytoma (PXA)
| Polysomy 3, polysomy 7 observed; '''Loss:''' monosomy 9 / 9p deletion
+
| Polysomy 3, polysomy 7 observed<br>
 +
'''Loss:''' monosomy 9 / 9p deletion
 
| '''Mutations:''' BRAF V600E in ~60%; TP53 (5%)<br>
 
| '''Mutations:''' BRAF V600E in ~60%; TP53 (5%)<br>
 
'''Loss:''' CDKN2A/CDKN2B  
 
'''Loss:''' CDKN2A/CDKN2B  
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|IDH-mutant  
 
|IDH-mutant  
 
|'''Gain:''' 1q, 2q, 3q, 7, 16p, 17q, 21q<br>
 
|'''Gain:''' 1q, 2q, 3q, 7, 16p, 17q, 21q<br>
'''Loss:''' 6q, 8q, 9p, 9q, 10q, 13q, 17p, 22q
+
'''Loss:''' 6q, 8q, 9p, 9q, 10q, 13q, 17p, 22q<br>
 
''' Chromothripsis:''' observed
 
''' Chromothripsis:''' observed
 
|'''Loss:''' PTEN, RB1, TP53, CDKN2A/B/C  
 
|'''Loss:''' PTEN, RB1, TP53, CDKN2A/B/C