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Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray (view source)
Revision as of 13:42, 15 November 2018
, 13:42, 15 November 2018no edit summary
| PMID:26829751; PMID:23633565; PMID:26778052 PMID:23583981
| PMID:26829751; PMID:23633565; PMID:26778052 PMID:23583981
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| Ganglioglioma
| Only 30% are abnormal by karyotype '''Gain:''' polysomy 7
| '''Mutations:''' BRAF V600E in 20-60% of cases (can be concurrent with CDKN2A homozygous deletion); '''Fusions:''' KIAA1549-BRAF
| Generally indolent tumors for which surgical resection can be curative
| PMID:25461780; PMID:23583981; PMID:11996800 PMID:23609006; PMID:29880043
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