Changes

iAMP21 is an intrachromosomal amplification of Chromosome 21 which includes the genes RUNX1, miR-802 among others.  This amplification occurs in about 1.5-2% of all Acute Lymphocytic Leukemia cases tested and is associated with poor prognostication (5).  

iAMP21 is an intrachromosomal amplification of Chromosome 21 which includes the genes RUNX1, miR-802 among others.  This amplification occurs in about 1.5-2% of all Acute Lymphocytic Leukemia cases tested and is associated with poor prognostication (5).  

'''T-cell Acute Lymphocytic Leukemia (T-ALL)'''

'''[http://www.ccga.io/index.php/T-ALL T-cell Acute Lymphocytic Leukemia (T-ALL)]'''

RUNX1 mutations have bee described in 20% o patients with early T-cell precursor acute lymphoblastic leukemia (ETP-ALL)(6).

 

RUNX1 mutations have bee described in 20% of patients with early T-cell precursor acute lymphoblastic leukemia (ETP-ALL)(6).

'''B-cell Acute Lymphocytic Leukemia (B-ALL)'''   

'''B-cell Acute Lymphocytic Leukemia (B-ALL)'''