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RUNX1 (view source)

86 bytes added , 17:02, 27 June 2018

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==Genomic Location==

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'''Cytoband:''' ~~Put your text here. EXAMPLE:~~ 21q22.12

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'''Cytoband:''' 21q22.12

'''Genomic Coordinates:'''

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~~Put your text here~~

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chr21:36,160,098-37,376,965 [hg19]

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~~EXAMPLE~~: ~~chr17:7~~,~~571,720-7,590,868 [hg19]~~

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chr21:34,787,801-36,004,667 [hg38]

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~~EXAMPLE: chr21:940~~,~~414~~ - 1,~~201~~,~~911~~ [hg38]

==Cancer Category/Type==

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~~Put your text here~~

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Acute Myeloid Leukemia (AML); Chromic Myeloid Leukemia (CML)

==Gene Overview==

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~~Put your text here~~.

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Heterodimer with CBFB. RUNX1 binds DNA as a monomer and through the Runt domain. DNA-binding is increased by heterodimerization

==Common Alteration Types==

436

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