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| − | __TOC__
| + | ==General Disease Overview / Description of Cancer Category== |
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| − | ==Cancer Category/Type== | |
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| − | Put your text here
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| − | ==Cancer Sub-Classification / Subtype==
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| − | Put your text here
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| − | ==Definition / Description of Disease==
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| − | ==Synonyms / Terminology==
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| − | ==Epidemiology / Prevalence==
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| − | Put your text here
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| − | ==Clinical Features==
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| − | Put your text here
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| − | ==Sites of Involvement==
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| − | Put your text here
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| − | ==Morphologic Features==
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| − | Put your text here
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| − | ==Immunophenotype==
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| − | Put your text here and/or fill in the table
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| − | {| class="wikitable sortable"
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| − | ! Finding !! Marker
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| − | |Positive (universal) || EXAMPLE CD1
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| − | |Positive (subset) || EXAMPLE CD2
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| − | |Negative (universal) || EXAMPLE CD3
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| − | |Negative (subset) || EXAMPLE CD4
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| − | |}
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| − | ==Chromosomal Rearrangements (Gene Fusions)==
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| − | Put your text here and/or fill in the table
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| − | {| class="wikitable sortable"
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| − | ! Chromosomal Rearrangement !! Genes in Fusion (5’ or 3’ Segments) !! Pathogenic Derivative !! Prevalence
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| − | |EXAMPLE t(9;22)(q34;q11.2) || EXAMPLE 3'ABL1 / 5'BCR || EXAMPLE der(22) || EXAMPLE 5%
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| − | |EXAMPLE t(8;21)(q22;q22) || EXAMPLE 5'RUNX1 / 3'RUNXT1 || EXAMPLE der(8) || EXAMPLE 5%
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| − | ==Characteristic Chromosomal Aberrations / Patterns==
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| − | ==Genomic Gain/Loss/LOH==
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| − | Put your text here and/or fill in the table
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| − | {| class="wikitable sortable"
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| − | ! Chromosome Number !! Gain/Loss/Amp/LOH !! Region
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| − | |EXAMPLE 8 || EXAMPLE Gain || EXAMPLE chr8:0-1000000
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| − | |EXAMPLE 7 || EXAMPLE Loss || EXAMPLE chr7:0-1000000
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| − | ==Gene Mutations (SNV/INDEL)==
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| − | Put your text here and/or fill in the tables
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| − | {| class="wikitable sortable"
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| − | ! Gene !! Mutation !! Oncogene/Tumor Suppressor/Other !! Presumed Mechanism (LOF/GOF/Other; Driver/Passenger) !! Prevalence (COSMIC/TCGA/Other)
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| − | | EXAMPLE TP53 || EXAMPLE R273H || EXAMPLE Tumor Suppressor || EXAMPLE LOF || EXAMPLE 20%
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| − | ===Other Mutations===
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| − | {| class="wikitable sortable"
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| − | ! Type !! Gene/Region/Other
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| − | | Concomitant Mutations || EXAMPLE IDH1 R123H
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| − | | Secondary Mutations || EXAMPLE Trisomy 7
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| − | |Mutually Exclusive || EXAMPLE EGFR Amplification
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| − | |}
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| − | ==Epigenomics (Methylation)==
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| − | ==Genes and Main Pathways Involved==
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| − | ==Diagnostic Testing Methods==
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| | Put your text here | | Put your text here |
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| − | ==Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)== | + | ==WHO Classification Pages (Includes Links to Content)== |
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| − | Put your text here | + | Put your text here, EXAMPLE #[[Chromophobe renal cell carcinoma]] |
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| − | ==Familial Forms== | + | ==Other Related Pages (Includes Links to Content)== |
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| − | Put your text here | + | Put your text here, EXAMPLE #[[Acute Myeloid Leukemia (AML) with Mutated FLT3]] |
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| − | ==Other Information== | + | ==Additional Information== |
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| | Put your text here | | Put your text here |
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| − | ==Links==
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| − | Put your links here
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| | ==References== | | ==References== |
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| | === EXAMPLE Book === | | === EXAMPLE Book === |
| − | #Arber DA, et al., (2008). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4thedition.Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, Editors. IARC Press: Lyon, France, p117-118. | + | #Arber DA, et al., (2008). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, Editors. IARC Press: Lyon, France, p117-118. |
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| | === EXAMPLE Journal Article === | | === EXAMPLE Journal Article === |