Changes

o NGS for ''CUX1'' mutations

o NGS for ''CUX1'' mutations

[[File:Example.jpg|center]]

[[File:CUX1_deletion.jpg|center]]

'''Figure 1.'''  Chromosome genomic array testing (CGAT) demonstrating a small deletion of 7q and a large copy-neutral loss of heterozygosity of 7q.  Bone marrow samples were analyzed using CytoScan HD (Affymetrix Inc.).  The allelic tracks of chromosome 7 are shown in the upper panels and the smoothed copy number tracks are shown in lower panels.  The arrows point to the ''CUX1'' gene locus at 7q22.1.  One patient (in blue color, with the diagnosis of chronic myelomonocytic leukemia) displayed a 439-Kb deletion of ''CUX1'' as the sole abnormality.  Another patient (in orange color, with the diagnosis of MDS) showed a terminal 7q cnLOH starting at the ''CUX1'' locus, also as the sole abnormality.  (Image provided by M. Fang; copyright Fred Hutchinson Cancer Research Center.)

'''Figure 1.'''  Chromosome genomic array testing (CGAT) demonstrating a small deletion of 7q and a large copy-neutral loss of heterozygosity of 7q.  Bone marrow samples were analyzed using CytoScan HD (Affymetrix Inc.).  The allelic tracks of chromosome 7 are shown in the upper panels and the smoothed copy number tracks are shown in lower panels.  The arrows point to the ''CUX1'' gene locus at 7q22.1.  One patient (in blue color, with the diagnosis of chronic myelomonocytic leukemia) displayed a 439-Kb deletion of ''CUX1'' as the sole abnormality.  Another patient (in orange color, with the diagnosis of MDS) showed a terminal 7q cnLOH starting at the ''CUX1'' locus, also as the sole abnormality.  (Image provided by M. Fang; copyright Fred Hutchinson Cancer Research Center.)