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==Cancer Category/Type==
==Cancer Category/Type==
[[Plasma Cell Neoplasms|Plasma Cell Neoplasm]]
[[HAEM4:Plasma Cell Neoplasms|Plasma Cell Neoplasm]]
==Cancer Sub-Classification / Subtype==
==Cancer Sub-Classification / Subtype==
[[Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
[[HAEM4:Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
==Definition / Description of Disease==
==Definition / Description of Disease==
==Gene Mutations (SNV/INDEL)==
==Gene Mutations (SNV/INDEL)==
A study was conducted in 20 patients of POEMS syndrome. The study showed 7 gene shaving recurrent somatic gene mutations involved in POEMS syndrome. It is important to know that none of the important gene mutations involved in MM such as NRAS, KRAS, BRAF, and TP53 were found in POEMS syndrome patients.<ref>{{Cite journal|last=Nagao|first=Yuhei|last2=Mimura|first2=Naoya|last3=Takeda|first3=June|last4=Yoshida|first4=Kenichi|last5=Shiozawa|first5=Yusuke|last6=Oshima|first6=Motohiko|last7=Aoyama|first7=Kazumasa|last8=Saraya|first8=Atsunori|last9=Koide|first9=Shuhei|date=2019-07|title=Genetic and transcriptional landscape of plasma cells in POEMS syndrome|url=https://www.nature.com/articles/s41375-018-0348-x|journal=Leukemia|language=en|volume=33|issue=7|pages=1723–1735|doi=10.1038/s41375-018-0348-x|issn=1476-5551}}</ref> [[Plasma Cell Neoplasms]]
A study was conducted in 20 patients of POEMS syndrome. The study showed 7 gene shaving recurrent somatic gene mutations involved in POEMS syndrome. It is important to know that none of the important gene mutations involved in MM such as NRAS, KRAS, BRAF, and TP53 were found in POEMS syndrome patients.<ref>{{Cite journal|last=Nagao|first=Yuhei|last2=Mimura|first2=Naoya|last3=Takeda|first3=June|last4=Yoshida|first4=Kenichi|last5=Shiozawa|first5=Yusuke|last6=Oshima|first6=Motohiko|last7=Aoyama|first7=Kazumasa|last8=Saraya|first8=Atsunori|last9=Koide|first9=Shuhei|date=2019-07|title=Genetic and transcriptional landscape of plasma cells in POEMS syndrome|url=https://www.nature.com/articles/s41375-018-0348-x|journal=Leukemia|language=en|volume=33|issue=7|pages=1723–1735|doi=10.1038/s41375-018-0348-x|issn=1476-5551}}</ref> [[HAEM4:Plasma Cell Neoplasms]]
==Links==
==Links==
[[Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
[[HAEM4:Plasma Cell Neoplasms with Associated Paraneoplastic Syndrome]]
==References==
==References==