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HAEM4:Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS) (view source)
Revision as of 16:24, 4 December 2023
, 16:24, 4 December 2023no edit summary
{{DISPLAYTITLE:Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)}}
<blockquote class='blockedit'>{{Box-round|title=PREVIOUS EDITION|This page from the 4th edition of Haematolymphoid Tumours is being updated. See 5th edition [[HAEM5:Table_of_Contents|Table of Contents]].
}}</blockquote>
==Primary Author(s)*==
==Primary Author(s)*==
==Characteristic Chromosomal Aberrations / Patterns==
==Characteristic Chromosomal Aberrations / Patterns==
About 10% of MDS-RS-SLD and 50% of MDS-RS-MLD have cytogenetic abnormalities [Cancer Cytogenetics]. These abnormalities mostly involve in single chromosome and are not specific for these disease entities. +8 is the most common chromosome abnormalities in MDS-RS and additional chromosomes reported include -7, 20q-, and -5 <ref>{{Cite journal|last=R|first=Ohba|last2=K|first2=Furuyama|last3=K|first3=Yoshida|last4=T|first4=Fujiwara|last5=N|first5=Fukuhara|last6=Y|first6=Onishi|last7=A|first7=Manabe|last8=E|first8=Ito|last9=K|first9=Ozawa|date=2013|title=Clinical and Genetic Characteristics of Congenital Sideroblastic Anemia: Comparison With Myelodysplastic Syndrome With Ring Sideroblast (MDS-RS)|url=https://pubmed.ncbi.nlm.nih.gov/22983749/|language=en|doi=10.1007/s00277-012-1564-5|pmc=PMC3536986|pmid=22983749}}</ref>. For chromosome abnormalities and prognostic values in MDS, please refer to [[Myelodysplastic Syndromes (MDS)|MDS]].
About 10% of MDS-RS-SLD and 50% of MDS-RS-MLD have cytogenetic abnormalities [Cancer Cytogenetics]. These abnormalities mostly involve in single chromosome and are not specific for these disease entities. +8 is the most common chromosome abnormalities in MDS-RS and additional chromosomes reported include -7, 20q-, and -5 <ref>{{Cite journal|last=R|first=Ohba|last2=K|first2=Furuyama|last3=K|first3=Yoshida|last4=T|first4=Fujiwara|last5=N|first5=Fukuhara|last6=Y|first6=Onishi|last7=A|first7=Manabe|last8=E|first8=Ito|last9=K|first9=Ozawa|date=2013|title=Clinical and Genetic Characteristics of Congenital Sideroblastic Anemia: Comparison With Myelodysplastic Syndrome With Ring Sideroblast (MDS-RS)|url=https://pubmed.ncbi.nlm.nih.gov/22983749/|language=en|doi=10.1007/s00277-012-1564-5|pmc=PMC3536986|pmid=22983749}}</ref>. For chromosome abnormalities and prognostic values in MDS, please refer to [[HAEM4:Myelodysplastic Syndromes (MDS)|MDS]].
==Genomic Gain/Loss/LOH==
==Genomic Gain/Loss/LOH==
==Notes==
==Notes==
<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.
<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.
[[Category:HAEM4]] [[Category:DISEASE]]