Global Template

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Global Template

Primary Author(s)

Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.

Cancer Category/Type

Cancer Sub-Classification / Subtype

Definition / Description of Disease

Synonyms / Terminology

Epidemiology / Prevalence

Clinical Features

Sites of Involvement

Morphologic Features

Immunophenotype

Finding Marker
Positive (universal) CD1
Positive (subset) CD2
Negative (universal) CD3
Negative (subset) CD4

Additional Description:

Chromosomal Rearrangements (Gene Fusions)

Chromosomal Rearrangement Genes in Fusion (5’ or 3’ Segments) Pathogenic Derivative Prevalence


Additional Description:

Characteristic Chromosomal Aberrations / Patterns

Genomic Gain/Loss/LOH

Chromosome Number Gain/Loss/Amp/LOH Region

Additional Description:

Gene Mutations (SNV/INDEL)

Gene Mutation Oncogene/Tumor Suppressor/Other Presumed Mechanism (LOF/GOF/Other; Driver/Passenger) Prevalence (COSMIC/TCGA/Other)

Additional Description:

Other Mutations Concomitant Mutations Secondary Mutations Mutually Exclusive Additional Description:

Epigenomics (Methylation)

Genes and Main Pathways Involved

Diagnostic Testing Methods

Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)

Familial Forms

Other Information

Links

References

Reference Example, BOOK

  1. Arber DA, Brunning RD, Le Beau MM, Falini B, Vardiman JW, Porwit A, Thiele J, Bloomfield CD (2008). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4thedition.Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, Editors. IARC Press: Lyon, France, p117-118.

Reference Example, Journal Article

  1. Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GCF, Chan LC, Squire J, Scherer SW and Hitzler JK (2001). Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet 28:220-221, PMID 11431691.