Germline Cancer Predisposition Genes

From Compendium of Cancer Genome Aberrations
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Gene Symbol Chromosome Band Cancer Syndrome Tumour Types Arising
ALK 2p23 familial neuroblastoma neuroblastoma
APC 5q21 adenomatous polyposis coli; Turcot syndrome colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS
ATM 11q22.3 ataxia-telangiectasia leukaemia, lymphoma, medulloblastoma, glioma
ATR 3q23 familial cutaneous telangiectasia and cancer sydrome oropharyngeal
AXIN2 17q24.1 oligodontia-colorectal cancer syndrome colorectal carcinoma
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