1,190
edits
Changes
no edit summary
__TOC__
__TOC__
== Breast Tumors WHO Classification ==
== CNS Tumors WHO (2016) Classification ==
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Diffuse astrocytic and oligodendroglial tumors'''
<div class="mw-collapsible-content">
<div class="mw-collapsible-content">
:: Tubular carcinoma and cribriform carcinoma
:Diffuse astrocytoma, IDH-mutant
:: Carcinoma with medullary features
::Gemistocytic astrocytoma, IDH-mutant
:: Metaplastic carcinoma
:Diffuse astrocytoma, IDH-wildtype
:: Carcinoma with apocrine differentiation
:Diffuse astrocytoma, NOS
:: Salivary gland/skin adnexal type tumours
:Anaplastic astrocytoma, IDH-mutant
:: Adenoid cystic carcinoma
:Anaplastic astrocytoma, IDH-wildtype
:: Mucoepidermoid carcinoma
:Anaplastic astrocytoma, NOS
:: Polymorphous carcinoma
:Glioblastoma, IDH-wildtype
:: Mucinous carcinoma and carcinoma withbignet-ring-cell differentiation
::Giant cell glioblastoma
:: Carcinoma with neuroendocrine features
::Gliosarcoma
:: Invasive papillary carcinoma
::Epithelioid glioblastoma
:: Invasive micropapillary carcinoma
:Glioblastoma, IDH-mutant
:: Inflammatory carcinoma
:Glioblastoma, NOS
:: Bilateral breast carcinoma and non-synchronous breast carcinoma
:Diffuse midline glioma, H3 K27M–mutant
:: Secretory carcinoma
:Oligodendroglioma, IDH-mutant and 1p/19q-codeleted
:: Oncocytic carcinoma
:Oligodendroglioma, NOS 69
:: Sebaceous carcinoma
:Anaplastic oligodendroglioma, IDH-mutant and 1p/19q-codeleted
:Anaplastic oligodendroglioma, NOS
:: Glycogen-rich clear cell carcinoma
:Oligoastrocytoma, NOS
:: Acinic cell carcinoma
:Anaplastic oligoastrocytoma, NOS
</div>
</div>
</div>
</div>
:'''Lobular neoplasia'''
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:'''Intraductal proliferative lesions'''
'''Other astrocytic tumors'''
:: Usual ductal hyperplasia
<div class="mw-collapsible-content">
:: Columnar cell lesions
:Pilocytic astrocytoma
:: Atypical ductal hyperplasia
::Pilomyxoid astrocytoma
:: Ductal carcinoma in situ
:Subependymal giant cell astrocytoma
:'''Microinvasive carcinoma'''
:Pleomorphic xanthoastrocytoma
:'''Intraductal papillary lesions'''
:Anaplastic pleomorphic xanthoastrocytoma
:: Intraductal papilloma
</div>
:: Intraductal papillary carcinoma
</div>
:: Encapsulated papillary carcinoma
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:: Solid papillary carcinoma
'''Ependymal tumors'''
:'''Benign epithelial proliferations'''
<div class="mw-collapsible-content">
:: Adenosis, sclerosing adenosis and
:Subependymoma
:: apocrine adenosis
:Myxopapillary ependymoma
:: Microglandular adenosis,
:Ependymoma
:: atypical microglandular adenosis and
::Papillary ependymoma
:: microglandular adenosis with carcinoma
::Clear cell ependymoma
:: Radial scar and complex sclerosing lesion
::Tanycytic ependymoma
:: Tubular adenoma
:Ependymoma, RELA fusion–positive
:: Lactating adenoma
:Anaplastic ependymoma
:: Apocrine adenoma
</div>
:: Ductal adenoma
</div>
:: Pleomorphic adenoma
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:'''Myoepithelial and epithelial–myoepithelial lesions'''
'''Other gliomas'''
:: Myoepithelial and epithelial–myoepithelial lesions
<div class="mw-collapsible-content">
:: Adenomyoepithelioma and adenomyoepithelioma with carcinoma
:Chordoid glioma of the third ventricle
:'''Mesenchymal tumours'''
:Angiocentric glioma
:: Nodular fasciitis
:Astroblastoma
:: Benign vascular lesions
</div>
:: Pseudoangiomatous stromal hyperplasia
</div>
:: Myofibroblastoma
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:: Desmoid-type fibromatosis
'''Choroid plexus tumors'''
:: Inflammatory myofibroblastic tumour
<div class="mw-collapsible-content">
:: Lipoma
:Choroid plexus papilloma
:: Granular cell tumour and benign peripheral
:Atypical choroid plexus papilloma
:: nerve-sheath tumour
:Choroid plexus carcinoma
:: Angiosarcoma
</div>
:: Liposarcoma
</div>
:: Rhabdomyosarcoma
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:: Osteosarcoma
'''Neuronal and mixed neuronal–glial tumors'''
:: Leiomyoma and leiomyosarcoma
<div class="mw-collapsible-content">
:'''Fibroepithelial tumours'''
:Dysembryoplastic neuroepithelial tumour
:: Fibroadenoma
:Gangliocytoma
:: Phyllodes tumour
:Ganglioglioma
:: Hamartoma
:Anaplastic ganglioglioma
:'''Tumours of the nipple'''
:Dysplastic cerebellar gangliocytoma (Lhermitte–Duclos disease)
:: Nipple adenoma
:Desmoplastic infantile astrocytoma and ganglioglioma
:: Syringomatous tumour
:Papillary glioneuronal tumour
:: Paget disease
:Rosette-forming glioneuronal tumour
:Diffuse leptomeningeal glioneuronal tumour
:: Diffuse large B-cell lymphoma
:Central neurocytoma
:: Burkitt lymphoma
:Extraventricular neurocytoma
:: T-cell lymphoma
:Cerebellar liponeurocytoma
:: Extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue
:Paraganglioma
:: Follicular lymphoma
</div>
:'''Metastases of extramammary malignancies to the breast'''
</div>
:'''Tumors of the male breast'''
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:: Gynaecomastia
'''Tumors of the pineal region'''
:: Carcinoma of the male breast
<div class="mw-collapsible-content">
:'''Genetic susceptibility: inherited syndromes'''
:Pineocytoma
:: Inherited syndromes associated with an increased risk of breast cancer: Introduction
:Pineal parenchymal tumour of intermediate differentiation
:: BRCA1 and BRCA2 syndromes
:Pineoblastoma
:: Li-Fraumeni syndrome
:Papillary tumour of the pineal region
:: Ataxia telangiectasia syndrome
</div>
:: Cowden syndrome
</div>
:: Lynch syndrome
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
:: Other breast cancer-predisposing genes
'''Embryonal tumors'''
<div class="mw-collapsible-content">
:Medulloblastoma
:Medulloblastoma, NOS
::Medulloblastomas, genetically defined
::Medulloblastoma, WNT-activated
::Medulloblastoma, SHH-activated and TP53-mutant
::Medulloblastoma, SHH-activated and TP53-wildtype
::Medulloblastoma, non-WNT/non-SHH
:Medulloblastomas, histologically defined
::Medulloblastoma, classic
::Desmoplastic/nodular medulloblastoma
::Medulloblastoma with extensive nodularity
::Large cell / anaplastic medulloblastoma
:Embryonal tumour with multilayered rosettes, C19MC-altered
:Embryonal tumour with multilayered rosettes, NOS
:Other CNS embryonal tumors
::Medulloepithelioma
::CNS neuroblastoma
::CNS ganglioneuroblastoma
::CNS embryonal tumour, NOS
:Atypical teratoid/rhabdoid tumour
:CNS embryonal tumour with rhabdoid features
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Tumors of the cranial and paraspinal nerves'''
<div class="mw-collapsible-content">
:Schwannoma
::Cellular schwannoma
::Plexiform schwannoma
:Melanotic schwannoma
:Neurofibroma
::Atypical neurofibroma
::Plexiform neurofibroma
:Perineurioma
:Hybrid nerve sheath tumors
:Malignant peripheral nerve sheath tumour (MPNST)
::MPNST with divergent differentiation
::Epithelioid MPNST
::MPNST with perineurial differentiation
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Meningiomas'''
<div class="mw-collapsible-content">
:Meningioma
:Meningioma variants
::Meningothelial meningioma
::Fibrous meningioma
::Transitional meningioma
::Psammomatous meningioma
::Angiomatous meningioma
::Microcystic meningioma
::Secretory meningioma
::Lymphoplasmacyte-rich meningioma
::Metaplastic meningioma
::Chordoid meningioma
::Clear cell meningioma
::Atypical meningioma
::Papillary meningioma
::Rhabdoid meningioma
::Anaplastic (malignant) meningioma
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Mesenchymal, non-meningothelial tumors'''
<div class="mw-collapsible-content">
:Solitary fibrous tumour / haemangiopericytoma
:Haemangioblastoma
:Haemangioma
:Epithelioid haemangioendothelioma
:Angiosarcoma
:Kaposi sarcoma
:Ewing sarcoma / peripheral primitive
::Neuroectodermal tumour
:Lipoma
:Angiolipoma
:Hibernoma
:Liposarcoma
:Desmoid-type fibromatosis
:Myofibroblastoma
:Inflammatory myofibroblastic tumour
:Benign fibrous histiocytoma
:Fibrosarcoma
:Undifferentiated pleomorphic sarcoma / malignant
::Fibrous histiocytoma
:Leiomyoma
:Leiomyosarcoma
:Rhabdomyoma
:Rhabdomyosarcoma
:Chondroma
:Chondrosarcoma
:Osteoma
:Osteochondroma
:Osteosarcoma
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Melanocytic tumors'''
<div class="mw-collapsible-content">
:Meningeal melanocytosis
:Meningeal melanomatosis
:Meningeal melanocytoma
:Meningeal melanoma
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Lymphomas'''
<div class="mw-collapsible-content">
:Diffuse large B-cell lymphoma of the CNS
::Corticoid-mitigated lymphoma
::Sentinel lesions
:Immunodeficiency-associated CNS lymphomas
::AIDS-related diffuse large B-cell lymphoma
::EBV+ diffuse large B-cell lymphoma, NOS
::Lymphomatoid granulomatosis
:Intravascular large B-cell lymphoma
:Miscellaneous rare lymphomas in the CNS
::Low-grade B-cell lymphomas
::T-cell and NK/T-cell lymphomas
::Anaplastic large cell lymphoma (ALK+/ALK–)
:MALT lymphoma of the dura
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Histiocytic tumors'''
<div class="mw-collapsible-content">
:Langerhans cell histiocytosis
:Erdheim–Chester disease
:Rosai–Dorfman disease
:Juvenile xanthogranuloma
:Histiocytic sarcoma
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Germ cell tumors'''
<div class="mw-collapsible-content">
:Germinoma
:Embryonal carcinoma
:Yolk sac tumour
:Choriocarcinoma
:Teratoma
::Mature teratoma
::Immature teratoma
:Teratoma with malignant transformation
:Mixed germ cell tumour
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Familial tumour syndromes'''
<div class="mw-collapsible-content">
:Neurofibromatosis type 1
:Neurofibromatosis type 2
:Schwannomatosis
:Von Hippel–Lindau disease
:Tuberous sclerosis
:Li–Fraumeni syndrome
:Cowden syndrome
:Turcot syndrome
::Mismatch repair cancer syndrome
::Familial adenomatous polyposis
:Naevoid basal cell carcinoma syndrome
:Rhabdoid tumour predisposition syndrome
</div>
</div>
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
'''Tumors of the sellar region'''
<div class="mw-collapsible-content">
:Craniopharyngioma
::Adamantinomatous craniopharyngioma
::Papillary craniopharyngioma
Granular cell tumour of the sellar region
Pituicytoma 332 Spindle cell oncocytoma
</div>
</div>
'''Metastatic tumors'''
== Miscellaneous Cancer Types ==
== Miscellaneous Cancer Types ==