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→Common Alteration Types
A small number of chronic myeloproliferative disorders patients have been described with BCR-FGFR1 and BCR-PDGFRA fusion genes [15].
A small number of chronic myeloproliferative disorders patients have been described with BCR-FGFR1 and BCR-PDGFRA fusion genes [15].
Somatic mutations of ''BCR'' have rarely been found spread throughout the gene (see '''[https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=BCR COSMIC June 2018]''', indicating these are probably mostly carrier mutations. The exception may be the point mutation D1106N in the RhoGAP domain which occurs more frequently and has been associated with Colon Cancer.
Somatic mutations of ''BCR'' have rarely been found spread throughout the gene (see '''[https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=BCR COSMIC June 2018]'''), indicating these are probably mostly carrier mutations. The exception may be the point mutation D1106N in the RhoGAP domain which occurs more frequently and has been associated with Colon Cancer.
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