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A small number of chronic myeloproliferative disorders patients have been described with BCR-FGFR1 and BCR-PDCFRA fusion genes (15).
A small number of chronic myeloproliferative disorders patients have been described with BCR-FGFR1 and BCR-PDCFRA fusion genes (15).
Small numbers of somatic mutation of BCR have been found spread throughout the BCR gene (see '''[https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=BCR COSMIC June 2018]''' , indicating these mutations are probably mostly carrier mutations. The exception may be the point mutation at D1106N in the RhoGAP domain and which occurs more frequently and has been associated with Colon Cancer.