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BCR (view source)

Revision as of 19:23, 21 June 2018

299 bytes added , 19:23, 21 June 2018

→‎Gene Overview

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==Gene Overview==

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The function of the normal BCR gene product is as a GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. The protein has serine/threonine kinase activity. (1)

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Mention that is haas coiled coil domain and prob. aggregates as Fusion BRC-ABL1.

==Common Alteration Types==

Brian.Davis

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