SET-NUP214
Revision as of 09:58, 31 August 2016 by ChrisWenzinger2 (talk | contribs)
Contributors
Daynna J. Wolff, PhD
Description
NUP214-SET is a fusion of the genes NUP214 (Nucleoporin 214kDa) and SET (SET Nuclear Proto-Oncogene), located at 9q34.13 and 9q34.11, respectively. The fusion has been described as resulting from a recurrent cryptic deletion, del(9)(q34.11q34.13).
Tumor Types
T-cell Acute Lymphoblastic Leukemia
Rare: [5]
Prevalence
Write your comments here
Genes Involved / Domains Affected
Write your comments here
Diagnostic Testing
Write your comments here
Clinical Significance
Write your comments here
Therapeutics
Write your comments here
Links
References
- ↑ Reference: Ann Clin Lab Sci. 2011 Summer;41(3):267-72. T-cell acute lymphoblastic leukemia associated with complex karyotype and SET-NUP214 rearrangement: a case study and review of the literature. Lee SG1, Park TS, Cho SY, Lim G, Park GJ, Oh SH, Cho EH, Chong SY, Huh JY. PMID: 22075511 http://www.ncbi.nlm.nih.gov/pubmed/22075511
- ↑ Ann Hematol. 2012 Feb;91(2):193-201. doi: 10.1007/s00277-011-1289-x. Epub 2011 Jul 1.
- ↑ Phenotypic and genetic characterization of adult T-cell acute lymphoblastic leukemia with del(9)(q34);SET-NUP214 rearrangement. Chae H1, Lim J, Kim M, Park J, Kim Y, Han K, Lee S, Min WS. PMID: http://www.ncbi.nlm.nih.gov/pubmed/21720744 Oncol Lett. 2014 Sep; 8(3): 959–962. Published online 2014 Jun 18. doi: 10.3892/ol.2014.2263 PMCID: PMC4114590
- ↑ NUP214 fusion genes in acute leukemia (Review) MIN-HANG ZHOU and QING-MING YANG PMID: http://www.ncbi.nlm.nih.gov/pubmed/25120641
- ↑ B-cell Lymphoid Leukemia Test Reference: Oncol Lett. 2016 Apr;11(4):2644-2650. Epub 2016 Feb 23. B-cell acute lymphoblastic leukemia associated with SET-NUP214 rearrangement: A case report and review of the literature. Zhu HH1, Zhao XS1, Qin YZ1, Lai YY1, Jiang H1 PMID:27073532