AML Copy Number Profile

Copy Number Losses

• MDS/AML with CUX1 deletion or del(7q22)
• Monosomy 7 in AML
• 17p loss in AML

Copy Number Gains

• Trisomy 8 in AML

Amplifications

None known.

Structural Rearrangements

1. Translocation t(3;3)(q21;q26.2) and Inversion inv(3)(q21q26.2) RPN1-MECOM
2. Translocation t(8;21)(q22;q22) RUNX1-RUNX1T1
3. Translocation t(6;9)(p23;q34) DEK-NUP214

TCGA Copy Number Profile

{{#iDisplay:http://54.191.11.12/AML.html%7C1200}}