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Myeloid proliferations and neoplasms (Overview Page Link)
Myeloid precursor lesions
Clonal Haematopoiesis - Clonal haematopoiesis - Clonal cytopenias of undetermined significance
Myeloproliferative neoplasms
Myeloproliferative neoplasms - Chronic myeloid leukaemia - Chronic neutrophilic leukaemia - Chronic eosinophilic leukaemia - Polycythaemia vera - Essential thrombocythaemia - Primary myelofibrosis - Juvenile myelomonocytic leukaemia - Myeloproliferative neoplasm, NOS
Mastocytosis
- Cutaneous mastocytosis - Systemic mastocytosis - Mast cell sarcoma
Myelodysplastic neoplasms
Myelodysplastic neoplasms, with defining genetic abnormalities - Myelodysplastic neoplasm with low blasts and 5q deletion - Myelodysplastic neoplasm with low blasts and SF3B1 mutation - Myelodysplastic neoplasm with biallelic TP53 inactivation Myelodysplastic neoplasms, morphologically defined - Myelodysplastic neoplasm with low blasts - Myelodysplastic neoplasm, hypoplastic - Myelodysplastic neoplasm with increased blasts Myelodysplastic neoplasms of childhood - Childhood myelodysplastic neoplasm with low blasts - Childhood myelodysplastic neoplasm with increased blasts
Myelodysplastic/myeloproliferative neoplasms
- Chronic myelomonocytic leukaemia - Myelodysplastic/myeloproliferative neoplasm with neutrophilia - Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis - Myelodysplastic/myeloproliferative neoplasm, NOS
Acute myeloid leukaemia
Acute myeloid leukaemia with defining genetic abnormalities - Acute promyelocytic leukaemia with PML::RARA fusion - Acute myeloid leukaemia with RUNX1::RUNX1T1 fusion - Acute myeloid leukaemia with CBFB::MYH11 fusion - Acute myeloid leukaemia with DEK::NUP214 fusion - Acute myeloid leukaemia with RBM15::MRTFA fusion - Acute myeloid leukaemia with BCR::ABL1 fusion - Acute myeloid leukaemia with KMT2A rearrangement - Acute myeloid leukaemia with MECOM rearrangement - Acute myeloid leukaemia with NUP98 rearrangement - Acute myeloid leukaemia with NPM1 mutation - Acute myeloid leukaemia with CEBPA mutation - Acute myeloid leukaemia, myelodysplasia-related - Acute myeloid leukaemia with other defined genetic alterations Acute myeloid leukaemia, defined by differentiation - Acute myeloid leukaemia with minimal differentiation - Acute myeloid leukaemia without maturation - Acute myeloid leukaemia with maturation - Acute basophilic leukaemia - Acute myelomonocytic leukaemia - Acute monocytic leukaemia - Acute erythroid leukaemia - Acute megakaryoblastic leukaemia Myeloid sarcoma - Myeloid sarcoma
Myeloid neoplasms, secondary
Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions - Myeloid neoplasm post cytotoxic therapy - Myeloid neoplasms associated with germline predisposition - Myeloid proliferations associated with Down syndrome
Myeloid/lymphoid neoplasms
Myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangement - Myeloid/lymphoid neoplasm with PDGFRA rearrangement - Myeloid/lymphoid neoplasm with PDGFRB rearrangement - Myeloid/lymphoid neoplasm with FGFR1 rearrangement - Myeloid/lymphoid neoplasm with JAK2 rearrangement - Myeloid/lymphoid neoplasm with FLT3 rearrangement - Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion - Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes
Acute leukaemias of mixed or ambiguous lineage
Acute leukaemia of ambiguous lineage with defining genetic abnormalities - Mixed-phenotype acute leukaemia with BCR::ABL1 fusion - Mixed-phenotype acute leukaemia with KMT2A rearrangement - Acute leukaemia of ambiguous lineage with other defined genetic alterations Acute leukaemia of ambiguous lineage, immunophenotypically defined - Mixed-phenotype acute leukaemia, B/myeloid - Mixed-phenotype acute leukaemia, T/myeloid - Mixed-phenotype acute leukaemia, rare types - Acute leukaemia of ambiguous lineage, NOS - Acute undifferentiated leukaemia
Histiocytic/Dendritic cell neoplasms (Overview Page Link)
Plasmacytoid dendritic cell neoplasms
Plasmacytoid dendritic cell neoplasms - Mature plasmacytoid dendritic cell proliferation associated with myeloid neoplasm - Blastic plasmacytoid dendritic cell neoplasm
Langerhans cell and other dendritic cell neoplasms
Langerhans cells neoplasms - Langerhans cell histiocytosis - Langerhans cell sarcoma Other dendritic cell neoplasms - Indeterminate dendritic cell tumour - Interdigitating dendritic cell sarcoma
Histiocyte/macrophage neoplasms
Histiocytic neoplasms - Juvenile xanthogranuloma - Erdheim-Chester disease - Rosai-Dorfman Disease - ALK-positive histiocytosis - Histiocytic sarcoma
B-cell lymphoid proliferations and lymphomas (Overview Page Link)
Tumour like lesions with B-cell predominance
- Reactive B-cell rich lymphoid proliferations that can mimic lymphoma - IgG4-related disease - Unicentric Castleman disease - Idiopathic multicentric Castleman disease - KSHV/HHV8-associated multicentric Castleman disease
Precursor B-cell neoplasms
B-lymphoblastic leukaemias/lymphomas - B-lymphoblastic leukaemia/lymphoma - B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy - B-lymphoblastic leukaemia/lymphoma with hypodiploidy - B-lymphoblastic leukaemia/lymphoma with iAMP21 - B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion - B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features - B lymphoblastic leukaemia/lymphoma with KMT2A rearrangement - B lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion - B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features - B lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion - B lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion - B lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion - B-lymphoblastic leukaemia/lymphoma with other defined genetic alterations - B-lymphoblastic leukaemia/lymphoma, NOS
Mature B-cell neoplasms
Pre-neoplastic and neoplastic small lymphocytic proliferations - Monoclonal B-cell lymphocytosis - Chronic lymphocytic leukaemia/small lymphocytic lymphoma Splenic B-cell lymphomas and leukaemias - Hairy cell leukaemia - Splenic marginal zone lymphoma - Splenic diffuse red pulp small B-cell lymphoma - Splenic B-cell lymphoma/leukaemia with prominent nucleoli Lymphoplasmacytic lymphoma - Lymphoplasmacytic lymphoma Marginal zone lymphoma - Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue - Primary cutaneous marginal zone lymphoma - Nodal marginal zone lymphoma - Paediatric nodal marginal zone lymphoma Follicular lymphoma - In situ follicular B-cell neoplasm - Follicular lymphoma - Paediatric-type follicular lymphoma - Duodenal-type follicular lymphoma Cutaneous follicle centre lymphoma - Primary cutaneous follicle centre lymphoma Mantle cell lymphoma - In situ mantle cell neoplasm - Mantle cell lymphoma - Leukaemic non-nodal mantle cell lymphoma Transformations of indolent B-cell lymphomas - Transformations of indolent B-cell lymphomas Large B-cell lymphomas - Diffuse large B-cell lymphoma, NOS - T-cell/histiocyte-rich large B-cell lymphoma - Diffuse large B-cell lymphoma / high grade B-cell lymphoma with MYC and BCL2 rearrangements - ALK-positive large B-cell lymphoma - Large B-cell lymphoma with IRF4 rearrangement - High grade B-cell lymphoma with 11q aberrations - Lymphomatoid granulomatosis - EBV-positive diffuse large B-cell lymphoma - Diffuse large B-cell lymphoma associated with chronic inflammation - Fibrin-associated large B-cell lymphoma - Fluid overload-associated large B-cell lymphoma - Plasmablastic lymphoma - Primary large B-cell lymphoma of immune-privileged sites - Primary cutaneous diffuse large B-cell lymphoma, leg type - Intravascular large B-cell lymphoma - Primary mediastinal large B-cell lymphoma - Mediastinal grey zone lymphoma - High-grade B-cell lymphoma, NOS Burkitt lymphoma - Burkitt lymphoma KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas - Primary effusion lymphoma - KSHV/HHV8-positive diffuse large B-cell lymphoma - KSHV/HHV8-positive germinotropic lymphoproliferative disorder Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation - Hyperplasias arising in immune deficiency/dysregulation - Polymorphic lymphoproliferative disorders arising in immune deficiency / dysregulation - EBV-positive mucocutaneous ulcer - Lymphomas arising in immune deficiency / dysregulation - Inborn error of immunity-associated lymphoid proliferations and lymphomas
Hodgkin lymphoma
- Classic Hodgkin lymphoma - Nodular lymphocyte predominant Hodgkin lymphoma
Plasma cell neoplasms and other diseases with paraproteins
Monoclonal gammopathies - Cold agglutinin disease - IgM monoclonal gammopathy of undetermined significance - Non-IgM monoclonal gammopathy of undetermined significance - Monoclonal gammopathy of renal significance Diseases with monoclonal immunoglobulin deposition - Immunoglobulin-related (AL) amyloidosis - Monoclonal immunoglobulin deposition disease Heavy chain diseases - Mu heavy chain disease - Gamma heavy chain disease - Alpha heavy chain disease Plasma cell neoplasms - Plasmacytoma - Plasma cell myeloma / multiple myeloma - Plasma cell neoplasms with associated paraneoplastic syndrome
T-cell and NK-cell lymphoid proliferations and lymphomas (Overview Page Link)
Tumour-like lesions with T-cell predominance
- Kikuchi-Fujimoto disease - Autoimmune lymphoproliferative syndrome - Indolent T-lymphoblastic proliferation
Precursor T-cell neoplasms
T-lymphoblastic leukaemia / lymphoma - T-lymphoblastic leukaemia / lymphoma, NOS - Early T-precursor lymphoblastic leukaemia / lymphoma
Mature T-cell and NK-cell neoplasms
Mature T-cell and NK-cell leukaemias - T-prolymphocytic leukaemia - T-large granular lymphocytic leukaemia - NK-large granular lymphocytic leukaemia - Adult T-cell leukaemia/lymphoma - Sezary syndrome - Aggressive NK-cell leukaemia Primary cutaneous T-cell lymphoid proliferations and lymphomas - Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorder - Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder - Mycosis fungoides - Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Lymphomatoid papulosis - Primary cutaneous CD30-positive T-cell lymphoproliferative disorder: Primary cutaneous anaplastic large cell lymphoma - Subcutaneous panniculitis-like T-cell lymphoma - Primary cutaneous gamma/delta T-cell lymphoma - Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma - Primary cutaneous peripheral T-cell lymphoma, NOS Intestinal T-cell and NK-cell lymphoid proliferations and lymphomas - Indolent T-cell lymphoma of the gastrointestinal tract - Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract - Enteropathy-associated T-cell lymphoma - Monomorphic epitheliotropic intestinal T-cell lymphoma - Intestinal T-cell lymphoma, NOS Hepatosplenic T-cell lymphoma - Hepatosplenic T-cell lymphoma Anaplastic large cell lymphoma - ALK-positive anaplastic large cell lymphoma - ALK-negative anaplastic large cell lymphoma - Breast implant-associated anaplastic large cell lymphoma Nodal T-follicular helper (TFH) cell lymphoma - Nodal TFH cell lymphoma, angioimmunoblastic-type - Nodal TFH cell lymphoma, follicular-type - Nodal TFH cell lymphoma, NOS Other peripheral T-cell lymphomas - Peripheral T-cell lymphoma, NOS EBV-positive NK-cell and T-cell lymphomas - EBV-positive nodal T- and NK-cell lymphoma - Extranodal NK/T-cell lymphoma EBV-positive T-cell and NK-cell lymphoid proliferations and lymphomas of childhood - Severe mosquito bite allergy - Hydroa vacciniforme lymphoproliferative disorder - Systemic chronic active EBV disease - Systemic EBV-positive T-cell lymphoma of childhood
Stroma-derived neoplasms of lymphoid tissues (Overview Page Link)
Mesenchymal dendritic cell neoplasms
Follicular dendritic cell neoplasms - Follicular dendritic cell sarcoma - EBV-positive inflammatory follicular dendritic cell sarcoma - Fibroblastic reticular cell tumour
Myofibroblastic tumours
Myofibroblastic tumour - Intranodal palisaded myofibroblastoma
Spleen-specific vascular-stromal tumours
Splenic vascular-stromal tumours - Littoral cell angioma - Splenic hamartoma - Sclerosing angiomatoid nodular transformation (SANT) of spleen
Genetic tumour syndromes (Overview Page Link)
- Fanconi anaemia - Bloom syndrome - Ataxia-telangiectasia syndrome - RASopathies