Test

Acute Myeloid Leukemia (AML) and Related Precursor Neoplasms

• Recurrent Genetic Abnormalities
  • t(8;21)(q22;q22.1); RUNX1-RUNX1T1
  • Acute Myeloid Leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11
• Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes
  • sub division
    • sub-sub-sub division

• Acute Myeloid Leukemia (AML) with Recurrent Genetic Abnormalities

  - Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22.1); RUNX1-RUNX1T1
  - Acute Myeloid Leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11
  - Acute Promyelocytic Leukemia (APL) with PML-RARA
  - Acute Myeloid Leukemia (AML) with t(9;11)(p21.3;q23.3); KMT2A-MLLT3
  - Acute Myeloid Leukemia (AML) with t(6;9)(p23;q34.1); DEK-NUP214
  - Acute Myeloid Leukemia (AML) with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2);GATA2, MECOM
  - Acute Myeloid Leukemia (AML) Megakaryoblastic with t(1;22)(p13.3;q13.1);RBM15-MKL1
  - Acute Myeloid Leukemia (AML) with BCR-ABL1
  - Acute Myeloid Leukemia (AML) with Mutated NPM1
  - Acute Myeloid Leukemia (AML) with Biallelic Mutations of CEBPA
  - Acute Myeloid Leukemia (AML) with Mutated RUNX1

• Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes

• Therapy-Related Myeloid Neoplasms

• Acute Myeloid Leukemia (AML), Not Otherwise Specified

  - Acute Myeloid Leukemia (AML) with Minimal Differentiation
  - Acute Myeloid Leukemia (AML) without Maturation
  - Acute Myeloid Leukemia (AML) with Maturation
  - Acute Myelomonocytic Leukemia
  - Acute Monoblastic and Monocytic Leukemia
  - Pure Erythroid Leukemia
  - Acute Megakaryoblastic Leukemia (AMKL)
  - Acute Basophilic Leukemia
  - Acute Panmyelosis with Myelofibrosis

• Myeloid Sarcoma

• Myeloid Proliferations Associated with Down Syndrome

  - Transient Abnormal Myelopoiesis (TAM) Associated with Down Syndrome
  - Myeloid Leukemia Associated with Down Syndrome

• Blastic Plasmacytoid Dendritic Cell Neoplasm

• Acute Leukemias of Ambiguous Lineage

  - Acute Undifferentiated Leukemia
  - Mixed Phenotype Acute Leukemia (MPAL) with t(9;22)(q34.1;q11.2); BCR-ABL1
  - Mixed Phenotype Acute Leukemia (MPAL) with t(v;11q23.3); KMT2A Rearranged
  - Mixed Phenotype Acute Leukemia (MPAL), B/Myeloid, Not Otherwise Specified
  - Mixed Phenotype Acute Leukemia (MPAL), T/Myeloid, Not Otherwise Specified
  - Mixed-Phenotype Acute Leukemia, Not Otherwise Specified (NOS), Rare Types
  - Acute Leukemias of Ambiguous Lineage, Not Otherwise Specified (NOS)

• Myeloid Neoplasms with Germline Predisposition

  - Acute Myeloid Leukaemia with Germline CEBPA Mutation
  - Myeloid Neoplasms with Germline DDX41 Mutation
  - Myeloid Neoplasms with Germline RUNX1 Mutation
  - Myeloid Neoplasms with Germline ANKRD26 Mutation
  - Myeloid Neoplasms with Germline ETV6 Mutation
  - Myeloid Neoplasms with Germline GATA2 Mutation

• Myelodysplastic Syndrome (MDS) with Single Lineage Dysplasia
• Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)
• Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia
• Myelodysplastic Syndrome (MDS) with Multilineage Dysplasia
• Myelodysplastic Syndrome (MDS) with Excess Blasts
• Myelodysplastic Syndrome (MDS) with Isolated del(5q)
• Myelodysplastic Syndrome (MDS), Unclassifiable
• Refractory Cytopenia of Childhood

• Chronic Myeloid Leukemia (CML), BCR-ABL1 Positive
• Chronic Neutrophilic Leukemia (CNL)
• Polycythemia Vera (PV)
• Primary Myelofibrosis (PMF)
• Essential Thrombocythemia (ET)
• Chronic Eosinophilic Leukemia, Not Otherwise Specified
• Myeloproliferative Neoplasm (MPN), Unclassifiable

1. Chronic Myelomonocytic Leukemia (CMML)
2. Atypical Chronic Myeloid Leukemia (aCML), BCR-ABL1 Negative
3. Juvenile Myelomonocytic Leukemia (JMML)
4. Myelodysplastic/Myeloproliferative Neoplasms with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T)
5. Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN), Unclassifiable