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Recurrent Genomic Alterations in Pediatric and Adult Central Nervous System Tumors Detected by Chromosomal Microarray (view source)
Revision as of 13:28, 16 November 2018
, 13:28, 16 November 2018no edit summary
| Anaplastic PXA, WHO grade III / Ganglioglioma, WHO Grade III
| Anaplastic PXA, WHO grade III / Ganglioglioma, WHO Grade III
| '''Loss:''' monosomy 9 / 9p deletion, but no diagnostic findings
| '''Loss:''' monosomy 9 / 9p deletion, but no diagnostic findings
| '''Mutation:''' BRAF V600E less common here than in PXA, grade II
| '''Mutation:''' BRAF V600E less common here than in PXA, grade II<br>
'''Loss:''' CDKN2A/CDKN2B
'''Loss:''' CDKN2A/CDKN2B
| CDKN2A/CDKN2B loss may correlate with anaplastic histology
| CDKN2A/CDKN2B loss may correlate with anaplastic histology
|Glioblastoma, WHO grade IV
|Glioblastoma, WHO grade IV
|IDH-mutant
|IDH-mutant
|'''Gain:''' 1q, 2q, 3q, 7, 16p, 17q, 21q
|'''Gain:''' 1q, 2q, 3q, 7, 16p, 17q, 21q<br>
'''Loss:''' 6q, 8q, 9p, 9q, 10q, 13q, 17p, 22q
'''Loss:''' 6q, 8q, 9p, 9q, 10q, 13q, 17p, 22q
''' Chromothripsis:''' observed
''' Chromothripsis:''' observed