ETV6

Primary Author(s)*

Brian Davis PhD

Synonyms

Put your text here

EXAMPLE: Tumor protein p53, LFS1, p53, BCC7, TRP53

Genomic Location

Cytoband: Put your text here. EXAMPLE: 17p13.1

Genomic Coordinates:

Put your text here

EXAMPLE: chr17:7,571,720-7,590,868 [hg19]

EXAMPLE: chr17:7,668,402-7,687,538 [hg38]

Cancer Category/Type

Put your text here

Gene Overview

Put your text here.

Common Alteration Types

Put your text here and/or fill in the table with an X where applicable

Copy Number Loss	Copy Number Gain	LOH	Loss-of-Function Mutation	Gain-of-Function Mutation	Translocation/Fusion
EXAMPLE: X	EXAMPLE: X	EXAMPLE: X	EXAMPLE: X	EXAMPLE: X	EXAMPLE: X

Internal Pages

Put your text here

EXAMPLE Germline Cancer Predisposition Genes

External Links

Put your text here - Include as applicable links to: 1) Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2) COSMIC, 3) CIViC, 4) St. Jude ProteinPaint, 5) Precision Medicine Knnowledgebase (Weill Cornell), 6) Cancer Index, 7) OncoKB, 8) My Cancer Genome, 9) UniProt, 10) Pfam, 11) GeneCards, 12) GeneReviews, and 13) Any gene-specific databases.

EXAMPLES

ETV6 by Atlas of Genetics and Cytogenetics in Oncology and Haematology - detailed gene information

ETV6 by COSMIC - sequence information, expression, catalogue of mutations

ETV6 by St. Jude ProteinPaint mutational landscape and matched expression data.

ETV6 by Precision Medicine Knowledgebase (Weill Cornell) - manually vetted interpretations of variants and CNVs

ETV6 by Cancer Index - gene, pathway, publication information matched to cancer type

ETV6 by OncoKB - mutational landscape, mutation effect, variant classification

ETV6 by My Cancer Genome - brief gene overview

ETV6 by UniProt - protein and molecular structure and function

ETV6 by Pfam - gene and protein structure and function information

ETV6 by GeneCards - general gene information and summaries

ETV6 by NCBI Gene - general gene information and summaries

ETV6 by OMIM - compendium of human genes and genetic phenotypes

ETV6 by LOVD(3) - Leiden Open Variation Database

ETV6 by TICdb - database of Translocation breakpoints In Cancer

References

1 .Arber DA, et al., (2008). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, Editors. IARC Press: Lyon, France, p117-118.

2. Schafer, E.S. . et al. (2015). Molecular Genetics of Acute Lymphoblastic Leukemia in The Molecular Basis of Cancer, 4th edition. Mendelsohn, J, Howley, PM, Israel, MA, Gray, JW, Thompson, CB. Editors. Elsevier Press: Philadelphia, USA, p395-406.

Notes

*Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.