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!Notes
!Notes
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|inv(14)(q11q32)
|inv(14)(q11.2q32.1)
t(14;14)(q11;q32)
t(14;14)(q11.2;q32.1)
|TCL1A/TRD|| ||inv(14) ~60%
|TCL1A/TRD|| ||inv(14) ~60%
t(14;14) ~25%
t(14;14) ~25%
|No
|No
|Recurrent secondary finding <ref>{{Cite journal|last=Matutes|first=E.|last2=Brito-Babapulle|first2=V.|last3=Swansbury|first3=J.|last4=Ellis|first4=J.|last5=Morilla|first5=R.|last6=Dearden|first6=C.|last7=Sempere|first7=A.|last8=Catovsky|first8=D.|date=1991-12-15|title=Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia|url=https://pubmed.ncbi.nlm.nih.gov/1742486|journal=Blood|volume=78|issue=12|pages=3269–3274|issn=0006-4971|pmid=1742486}}</ref>
|Recurrent secondary finding <ref>{{Cite journal|last=Matutes|first=E.|last2=Brito-Babapulle|first2=V.|last3=Swansbury|first3=J.|last4=Ellis|first4=J.|last5=Morilla|first5=R.|last6=Dearden|first6=C.|last7=Sempere|first7=A.|last8=Catovsky|first8=D.|date=1991-12-15|title=Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia|url=https://pubmed.ncbi.nlm.nih.gov/1742486|journal=Blood|volume=78|issue=12|pages=3269–3274|issn=0006-4971|pmid=1742486}}</ref>
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|6
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|11
|11
|Loss
|Loss
|11q23.3
|11q23.3
|ch11
|ch11q21-q23
|Yes
|Yes
|Yes
|Yes
|Frequent
|Frequent
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|5
|12
|Loss
|12p13
|chr12
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|13
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|13q14.3
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|In approximately (37%)
|In approximately (37%)
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|12
|17
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|22
|Loss
|Loss
|12p13
|Monosomy 22
|chr12
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|Yes
|Yes
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|Biallelic inactivation (missense mutations) of the ATM gene was demonstrated in virtually all sporadic cases of T-PLL (Dr. Jaffe book)
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|''EZH2''
|''EZH2''
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|Oncogene, TSG
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|''FBXW10''
|''FBXW10''
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|TSG
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|''CHEK2''
|''CHEK2''
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|TSG
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|''JAK1, JAK3, STAT5B''
|''IL2RG,'' ''JAK1, JAK3, STAT5B''
|Oncogene
|Oncogene
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|The mutations within this pathway typically occur in a mutually exclusive manner (Dr jaffe book)
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|''IL2RG''
|TP53
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|''ATM, CHEK2''
|''ATM, CHEK2''
|DNA damage repair pathway
|DNA damage repair pathway
|Genomic instability
|Genomic instability
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|''JAK1, JAK3, STAT5B''
|''JAK1, JAK3, STAT5B''