Difference between revisions of "IGH Rearrangements"
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| − | [[B-ALL|ALL]] | + | [[Category:Translocations in B-ALL]] |
| − | [[Lymphoma]] | + | |
| − | [[Multiple Myeloma]] | + | Immunoglobulin locus rearrangements occur in tumors arising from the B-cell lineage [[B-ALL|ALL]], [[Lymphoma]] and [[Multiple Myeloma]]. |
| − | BCL11B | + | IGH/K/L partner genes are numerous and include: |
| − | BACH2 | + | *BCL11B |
| − | CCND1 | + | *BACH2 |
| − | BCL2 | + | *CCND1 |
| − | BANK1 | + | *BCL2 |
| − | CCND3 | + | *BANK1 |
| − | CCND2 | + | *CCND3 |
| − | BCL10 | + | *CCND2 |
| − | FGFR3 | + | *BCL10 |
| − | CEBPA | + | *FGFR3 |
| − | BCL11A | + | *CEBPA |
| − | IRF4 | + | *[[DUX4]] |
| − | CEBPB | + | *BCL11A |
| − | BCL2 | + | *IRF4 |
| − | MAF | + | *CEBPB |
| − | CEBPD | + | *BCL2 |
| − | BCL3 | + | *MAF |
| − | MAFB | + | *CEBPD |
| − | CEBPE | + | *BCL3 |
| − | BCL6 | + | *MAFB |
| − | MMSET | + | *CEBPE |
| − | CEBPG | + | *BCL6 |
| − | BCL7A | + | *MMSET |
| − | MYC | + | *CEBPG |
| − | CRLF2 | + | *BCL7A |
| − | BCL8 | + | *MYC |
| − | [[EPOR]] | + | *[[CRLF2]] |
| − | CBAFA2T3 | + | *BCL8 |
| − | HOXA | + | *[[IGH-EPOR|EPOR]] |
| − | CCND1 | + | *CBAFA2T3 |
| − | ID4 | + | *HOXA |
| − | CCND2 | + | *CCND1 |
| − | IGF2BP1 | + | *ID4 |
| − | CCNE1 | + | *CCND2 |
| − | IL3 | + | *IGF2BP1 |
| − | CD44 | + | *CCNE1 |
| − | LCK | + | *IL3 |
| − | CDK6 | + | *CD44 |
| − | LMO1 | + | *LCK |
| − | CND3 | + | *CDK6 |
| − | LMO2 | + | *LMO1 |
| − | FCGR2A | + | *CND3 |
| − | LYL1 | + | *LMO2 |
| − | FCGR2B | + | *FCGR2A |
| − | MYC | + | *LYL1 |
| − | FOXP1 | + | *FCGR2B |
| − | NOTCH1 | + | *MYC |
| − | GPR34 | + | *FOXP1 |
| − | OLIG2 | + | *NOTCH1 |
| − | IRF4 | + | *GPR34 |
| − | TAL1 | + | *OLIG2 |
| − | IRF8 | + | *IRF4 |
| − | TAL2 | + | *TAL1 |
| − | IRTA1 | + | *IRF8 |
| − | TCL1 | + | *TAL2 |
| − | LHX2 | + | *IRTA1 |
| − | TLX1 | + | *TCL1 |
| − | MALT1 | + | *LHX2 |
| − | TLX3 | + | *TLX1 |
| − | MUC1 | + | *MALT1 |
| − | MYC | + | *TLX3 |
| − | NFKB2 | + | *MUC1 |
| − | PAFAH1A2 | + | *MYC |
| − | PAX5 | + | *NFKB2 |
| − | RCK | + | *PAFAH1A2 |
| − | SPIB | + | *PAX5 |
| − | ZPP36L1 | + | *RCK |
| + | *SPIB | ||
| + | *ZPP36L1 | ||
Latest revision as of 12:05, 11 August 2016
Immunoglobulin locus rearrangements occur in tumors arising from the B-cell lineage ALL, Lymphoma and Multiple Myeloma.
IGH/K/L partner genes are numerous and include:
- BCL11B
- BACH2
- CCND1
- BCL2
- BANK1
- CCND3
- CCND2
- BCL10
- FGFR3
- CEBPA
- DUX4
- BCL11A
- IRF4
- CEBPB
- BCL2
- MAF
- CEBPD
- BCL3
- MAFB
- CEBPE
- BCL6
- MMSET
- CEBPG
- BCL7A
- MYC
- CRLF2
- BCL8
- EPOR
- CBAFA2T3
- HOXA
- CCND1
- ID4
- CCND2
- IGF2BP1
- CCNE1
- IL3
- CD44
- LCK
- CDK6
- LMO1
- CND3
- LMO2
- FCGR2A
- LYL1
- FCGR2B
- MYC
- FOXP1
- NOTCH1
- GPR34
- OLIG2
- IRF4
- TAL1
- IRF8
- TAL2
- IRTA1
- TCL1
- LHX2
- TLX1
- MALT1
- TLX3
- MUC1
- MYC
- NFKB2
- PAFAH1A2
- PAX5
- RCK
- SPIB
- ZPP36L1