Difference between revisions of "Global Template"
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+ | {{Under Construction}} | ||
+ | ==Primary Author(s)*== | ||
− | + | Put your text here (Example: Jane Smith, PhD, Institute of Genomics) | |
__TOC__ | __TOC__ | ||
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==Immunophenotype== | ==Immunophenotype== | ||
− | Put your text here or fill in the table | + | Put your text here and/or fill in the table |
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
|- | |- | ||
− | ! Finding | + | !Finding!!Marker |
|- | |- | ||
− | |Positive (universal) || CD1 | + | |Positive (universal)||EXAMPLE CD1 |
|- | |- | ||
− | |Positive (subset) || CD2 | + | |Positive (subset)||EXAMPLE CD2 |
|- | |- | ||
− | |Negative (universal) || CD3 | + | |Negative (universal)||EXAMPLE CD3 |
|- | |- | ||
− | |Negative (subset) || CD4 | + | |Negative (subset)||EXAMPLE CD4 |
|} | |} | ||
− | |||
− | |||
− | |||
− | |||
==Chromosomal Rearrangements (Gene Fusions)== | ==Chromosomal Rearrangements (Gene Fusions)== | ||
− | Put your text here or fill in the table | + | Put your text here and/or fill in the table |
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
|- | |- | ||
− | ! Chromosomal Rearrangement !! Genes in Fusion (5’ or 3’ Segments) !! Pathogenic Derivative !! Prevalence | + | !Chromosomal Rearrangement!!Genes in Fusion (5’ or 3’ Segments)!!Pathogenic Derivative!!Prevalence |
|- | |- | ||
− | |t(9;22) || BCR | + | |EXAMPLE t(9;22)(q34;q11.2)||EXAMPLE 3'ABL1 / 5'BCR||EXAMPLE der(22)||EXAMPLE 5% |
|- | |- | ||
− | |t(8;21) || RUNX1 | + | |EXAMPLE t(8;21)(q22;q22)||EXAMPLE 5'RUNX1 / 3'RUNXT1||EXAMPLE der(8)||EXAMPLE 5% |
|} | |} | ||
− | |||
− | |||
− | |||
− | |||
==Characteristic Chromosomal Aberrations / Patterns== | ==Characteristic Chromosomal Aberrations / Patterns== | ||
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==Genomic Gain/Loss/LOH== | ==Genomic Gain/Loss/LOH== | ||
− | Put your text here or fill in the table | + | Put your text here and/or fill in the table |
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
|- | |- | ||
− | ! Chromosome Number !! Gain/Loss/Amp/LOH !! Region | + | !Chromosome Number!!Gain/Loss/Amp/LOH!!Region |
|- | |- | ||
− | | 8 || Gain || chr8:0-1000000 | + | |EXAMPLE 8||EXAMPLE Gain||EXAMPLE chr8:0-1000000 |
|- | |- | ||
− | |7 || Loss || chr7:0-1000000 | + | |EXAMPLE 7||EXAMPLE Loss||EXAMPLE chr7:0-1000000 |
|} | |} | ||
− | |||
− | |||
− | |||
− | |||
==Gene Mutations (SNV/INDEL)== | ==Gene Mutations (SNV/INDEL)== | ||
− | Put your text here or fill in the | + | Put your text here and/or fill in the tables |
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
|- | |- | ||
− | ! Gene !! Mutation !! Oncogene/Tumor Suppressor/Other !! Presumed Mechanism (LOF/GOF/Other; Driver/Passenger) !! Prevalence (COSMIC/TCGA/Other) | + | !Gene!!Mutation!!Oncogene/Tumor Suppressor/Other!!Presumed Mechanism (LOF/GOF/Other; Driver/Passenger)!!Prevalence (COSMIC/TCGA/Other) |
|- | |- | ||
− | | TP53 || R273H || Tumor Suppressor || LOF || 20% | + | |EXAMPLE TP53||EXAMPLE R273H||EXAMPLE Tumor Suppressor||EXAMPLE LOF||EXAMPLE 20% |
|} | |} | ||
− | === | + | ===Other Mutations=== |
− | + | {| class="wikitable sortable" | |
− | + | |- | |
− | + | !Type!!Gene/Region/Other | |
− | + | |- | |
− | + | |Concomitant Mutations||EXAMPLE IDH1 R123H | |
− | + | |- | |
− | + | |Secondary Mutations||EXAMPLE Trisomy 7 | |
− | + | |- | |
− | + | |Mutually Exclusive||EXAMPLE EGFR Amplification | |
+ | |} | ||
==Epigenomics (Methylation)== | ==Epigenomics (Methylation)== | ||
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==Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)== | ==Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)== | ||
− | Put your text here | + | Diagnosis: Put your text here |
+ | |||
+ | Prognosis: Put your text here | ||
+ | |||
+ | Therapeutic: Put your text here | ||
==Familial Forms== | ==Familial Forms== | ||
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==Links== | ==Links== | ||
− | Put your links here | + | Put your links here (use "Link" icon at top of page) |
==References== | ==References== | ||
+ | (use "Cite" icon at top of page) | ||
+ | <references /> | ||
+ | ===EXAMPLE Book=== | ||
− | + | #Arber DA, et al., (2017). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Arber DA, Hasserjian RP, Le Beau MM, Orazi A, and Siebert R, Editors. IARC Press: Lyon, France, p129-171. | |
− | #Arber DA, | ||
− | |||
− | |||
− | |||
− | == Notes == | + | ==Notes== |
<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome. | <nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome. |
Latest revision as of 08:41, 15 April 2021
This page is under construction |
Primary Author(s)*
Put your text here (Example: Jane Smith, PhD, Institute of Genomics)
Cancer Category/Type
Put your text here
Cancer Sub-Classification / Subtype
Put your text here
Definition / Description of Disease
Put your text here
Synonyms / Terminology
Put your text here
Epidemiology / Prevalence
Put your text here
Clinical Features
Put your text here
Sites of Involvement
Put your text here
Morphologic Features
Put your text here
Immunophenotype
Put your text here and/or fill in the table
Finding | Marker |
---|---|
Positive (universal) | EXAMPLE CD1 |
Positive (subset) | EXAMPLE CD2 |
Negative (universal) | EXAMPLE CD3 |
Negative (subset) | EXAMPLE CD4 |
Chromosomal Rearrangements (Gene Fusions)
Put your text here and/or fill in the table
Chromosomal Rearrangement | Genes in Fusion (5’ or 3’ Segments) | Pathogenic Derivative | Prevalence |
---|---|---|---|
EXAMPLE t(9;22)(q34;q11.2) | EXAMPLE 3'ABL1 / 5'BCR | EXAMPLE der(22) | EXAMPLE 5% |
EXAMPLE t(8;21)(q22;q22) | EXAMPLE 5'RUNX1 / 3'RUNXT1 | EXAMPLE der(8) | EXAMPLE 5% |
Characteristic Chromosomal Aberrations / Patterns
Put your text here
Genomic Gain/Loss/LOH
Put your text here and/or fill in the table
Chromosome Number | Gain/Loss/Amp/LOH | Region |
---|---|---|
EXAMPLE 8 | EXAMPLE Gain | EXAMPLE chr8:0-1000000 |
EXAMPLE 7 | EXAMPLE Loss | EXAMPLE chr7:0-1000000 |
Gene Mutations (SNV/INDEL)
Put your text here and/or fill in the tables
Gene | Mutation | Oncogene/Tumor Suppressor/Other | Presumed Mechanism (LOF/GOF/Other; Driver/Passenger) | Prevalence (COSMIC/TCGA/Other) |
---|---|---|---|---|
EXAMPLE TP53 | EXAMPLE R273H | EXAMPLE Tumor Suppressor | EXAMPLE LOF | EXAMPLE 20% |
Other Mutations
Type | Gene/Region/Other |
---|---|
Concomitant Mutations | EXAMPLE IDH1 R123H |
Secondary Mutations | EXAMPLE Trisomy 7 |
Mutually Exclusive | EXAMPLE EGFR Amplification |
Epigenomics (Methylation)
Put your text here
Genes and Main Pathways Involved
Put your text here
Diagnostic Testing Methods
Put your text here
Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)
Diagnosis: Put your text here
Prognosis: Put your text here
Therapeutic: Put your text here
Familial Forms
Put your text here
Other Information
Put your text here
Links
Put your links here (use "Link" icon at top of page)
References
(use "Cite" icon at top of page)
EXAMPLE Book
- Arber DA, et al., (2017). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Arber DA, Hasserjian RP, Le Beau MM, Orazi A, and Siebert R, Editors. IARC Press: Lyon, France, p129-171.
Notes
*Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.