Compendium of Cancer Genome Aberrations

Changes

Translocations et al. in Hematological Cancers (view source)

Revision as of 20:30, 2 March 2016

69 bytes removed ,  20:30, 2 March 2016
→‎Translocations
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|-
 
|-
 
|[[Translocation t(1;3)(p36;q21)|t(1;3)(p36;q21)]]
 
|[[Translocation t(1;3)(p36;q21)|t(1;3)(p36;q21)]]
−
|[[MDS]],[[ AML]]
+
|[[MDS]],[[AML]]
 
|[[PRDM16(MEL1)-RPN1]]
 
|[[PRDM16(MEL1)-RPN1]]
 
|-
 
|-
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|-
 
|-
 
|[[der(1;7)(q10;p10)]]
 
|[[der(1;7)(q10;p10)]]
−
|[[MDS]],[[ AML]],[[ MPD]]
+
|[[MDS]],[[AML]],[[ MPD]]
 
|
 
|
 
|-
 
|-
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|-
 
|-
 
|[[t(2;14)(p15;q32)]]
 
|[[t(2;14)(p15;q32)]]
−
|[[CLL]],[[ NHL]],[[ B-ALL]],[[ T-ALL]],[[ AML]]
+
|[[CLL]],[[ NHL]],[[ B-ALL]],[[ T-ALL]],[[AML]]
 
|
 
|
 
|-
 
|-
 
|[[t(3;3)(q21;q26.2) ]]
 
|[[t(3;3)(q21;q26.2) ]]
−
|[[MDS]],[[ AML]]
+
|[[MDS]],[[AML]]
 
|[[RPN1-MECOM(EVI1)]]
 
|[[RPN1-MECOM(EVI1)]]
 
|-
 
|-
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|-
 
|-
 
|[[t(6;9)(p23;q34) ]]
 
|[[t(6;9)(p23;q34) ]]
−
|[[MDS]],[[ AML]]
+
|[[MDS]],[[AML]]
 
|[[DEK-NUP214 (CAN)]]
 
|[[DEK-NUP214 (CAN)]]
 
|-
 
|-
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|-
 
|-
 
|[[t(8;16)(p11.2;p13.3)  A]]
 
|[[t(8;16)(p11.2;p13.3)  A]]
−
|[[AML M4]],[[ M5a]],[[ M5b]],[[ t-MDS]]
+
|[[AML]],[[t-MDS]]
 
|[[KAT6A(MYST3)-CREBBP(CBP)]]
 
|[[KAT6A(MYST3)-CREBBP(CBP)]]
 
|-
 
|-
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|-
 
|-
 
|[[t(9;11)(p22;q23)]]
 
|[[t(9;11)(p22;q23)]]
−
|[[AML mostly M5]],[[ M4]],[[ B-ALL]]
+
|[[AML]],[[B-ALL]]
 
|[[MLLT3(AF9)-KMT2A(MLL)]]
 
|[[MLLT3(AF9)-KMT2A(MLL)]]
 
|-
 
|-
 
|[[t(9;14)(p13;q32)]]
 
|[[t(9;14)(p13;q32)]]
−
|[[MM]],[[ CLL]],[[ DLBCL]],[[ FL]],[[ MCL splenic MZL]]
+
|[[MM]],[[CLL]],[[DLBCL]],[[ FL]],[[MCL splenic MZL]]
 
|[[PAX5-IGH]]
 
|[[PAX5-IGH]]
 
|-
 
|-
−
|[[t(9;22)(q34;q11.2) A B ]]
+
|[[t(9;22)(q34;q11.2)]]
 
|[[CML]],[[ B-ALL]],[[  T-ALL]]
 
|[[CML]],[[ B-ALL]],[[  T-ALL]]
 
|[[ABL1(ABL)-BCR]]
 
|[[ABL1(ABL)-BCR]]
 
|-
 
|-
−
|[[t(11;14)(q13;q32) A ]]
+
|[[t(11;14)(q13;q32)]]
 
|[[MCL]],[[ MM]]
 
|[[MCL]],[[ MM]]
 
|[[CCND1(BCL1)- IGH]]
 
|[[CCND1(BCL1)- IGH]]
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|[[BIRC3(API2)-MALT1]]
 
|[[BIRC3(API2)-MALT1]]
 
|-
 
|-
−
|[[t(11;19)(q23;p13.1) ]]
+
|[[t(11;19)(q23;p13.1)]]
 
|[[AML]]
 
|[[AML]]
 
|[[KMT2A(MLL)-ELL]]
 
|[[KMT2A(MLL)-ELL]]
 
|-
 
|-
−
|[[t(11;19)(q23;p13.3) ]]
+
|[[t(11;19)(q23;p13.3)]]
−
|[[B-ALL]],[[ AML]],[[ T-ALL]]
+
|[[B-ALL]],[[AML]],[[T-ALL]]
 
|[[KMT2A(MLL)-MLLT1(ENL)]]
 
|[[KMT2A(MLL)-MLLT1(ENL)]]
 
|-
 
|-
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|[[IGH-MAF]]
 
|[[IGH-MAF]]
 
|-
 
|-
−
|[[t(14;18)(q32;q21) ]]
+
|[[t(14;18)(q32;q21)]]
−
|[[BL]],[[ DLBCL]],[[ FL]],[[ CLL]]
+
|[[BL]],[[DLBCL]],[[FL]],[[CLL]]
 
|[[IGH-BCL2]]
 
|[[IGH-BCL2]]
 
|-
 
|-
 
|[[t(14;19)(q32;q13.3)]]
 
|[[t(14;19)(q32;q13.3)]]
−
|[[CLL]],[[ DLBCL]],[[ MCL]],[[ MZL]],[[ SLVL]]
+
|[[CLL]],[[DLBCL]],[[MCL]],[[MZL]],[[SLVL]]
 
|
 
|
 
|-
 
|-
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