Breast Cancer

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Contents

1 Primary Author(s)*

2 Graphical Data

2 General Disease Overview / Description of Cancer Category

3 WHO Classification Pages (Includes Links to Content)

4 Other Related Pages (Includes Links to Content)

5 Additional Information 6 References

6.1 EXAMPLE Book

6.2 EXAMPLE Journal Article

7 Notes

Primary Author(s)*

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Graphical Data Links

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Table 5: Genes with known hereditary risk associations in breast cancer according to National Comprehensive Cancer Network (NCCN) Guidelines (version 3.2019)

Gene	Associated Syndrome; Breast Cancer Subtype
ATM	Ataxia telangiectasia syndrome
BRCA1	BRCA-Related Breast/ Ovarian Cancer Syndrome; TNBC
BRCA2	BRCA-Related Breast/ Ovarian Cancer Syndrome; TNBC
CDH1	Hereditary Diffuse Gastric Cancer and Lobular Breast Cancer
CHEK2	Inherited breast cancer
NBN	Nijmegen Breakage Syndrome (autosomal recessive inheritance)
NF1	Neurofibromatosis type 1
PALB2	Fanconi anemia
PTEN	Cowden syndrome
STK11	Peutz-Jeghers syndrome
TP53	Li-Fraumeni syndrome

Inheritance is autosomal dominant with incomplete penetrance, unless otherwise specified

General Disease Overview / Description of Cancer Category

Put your text here

WHO Classification Pages

(Includes Links to Content)

Put your text here, EXAMPLE #Chromophobe renal cell carcinoma

Other Related Pages

(Includes Links to Content)

Put your text here, EXAMPLE #Acute Myeloid Leukemia (AML) with Mutated FLT3

Additional Information

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References

EXAMPLE Book Arber DA, et al., (2008). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, Editors. IARC Press: Lyon, France, p117-118.

EXAMPLE Journal Article Li Y, et al., (2001). Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet 28:220-221, PMID 11431691.

Notes

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