Changes

'''Acute Myeloid Leukemia (AML);'''  

'''Acute Myeloid Leukemia (AML);'''  

The most common chromosomal translocations is t(8;21)(q22;q22) in de novo AML (2) RUNX1-RUNX1T1. translocations confer a favorable prognosis in their respective diseases (2)  

The most common chromosomal translocations is t(8;21)(q22;q22) (RUNX1-RUNX1T1) in de novo AML, at approximately 7% (2, 6). This translocation confers a favorable prognosis in AML and other neoplasms (2, 5, 6). 

inv(16)(p13;q22) or t(16)(p13;q22), which disrupt CBFB the non-DNA-binding partner of RUNX1 and the MYH11 gene:  also translocation confer a favorable prognosis in their respective diseases (2)

inv(16)(p13;q22) or t(16)(p13;q22), which disrupt CBFB the non-DNA-binding partner of RUNX1 and the MYH11 gene:  also translocation confer a favorable prognosis in their respective diseases (2)

'''B-cell Acute Lymphocytic Leukemia (B-ALL)'''   

'''B-cell Acute Lymphocytic Leukemia (B-ALL)'''   

most common chromosomal translocations is t(12;21)(p13;q22) (ETV6-RUNX1) in B-cell acute lymphocytic leukemia (B-ALL) (2).  This translocation occurs in 25% of Pediatic B-ALL but only 2% of Adult B-ALL (  translocation confer a favorable prognosis in their respective diseases(2)

The most common chromosomal translocations is t(12;21)(p13;q22) (ETV6-RUNX1) in B-cell acute lymphocytic leukemia (B-ALL) (2).  This translocation occurs in 25% of Pediatric B-ALL but only 2% of Adult B-ALL (5). This translocation confers a favorable prognosis in B-ALL and other neoplasms (2, 5, 6).

 

'''Chromic Myeloid Leukemia (CML)'''

'''Chromic Myeloid Leukemia (CML)'''