Changes

==Gene Overview==

==Gene Overview==

The ''TP53'' gene is well-known tumor suppressor gene that has been implicated in many cancer types. (Wang, et al. 2018) The ''TP53'' protein product is involved in regulating the cell cycle pathway and can prevent replication if cell damage has occurred. (Hampp, et al. 2016)  Deletions, LOH, and loss of function (LOF) mutations have been associated with ''TP53''. These alterations often confer a poor prognosis [CITE] and chemoresistance [CITE].

The ''TP53'' gene is well-known tumor suppressor gene that has been implicated in many cancer types [1]. The ''TP53'' protein product is involved in regulating the cell cycle pathway and can prevent replication if cell damage has occurred [2]. Deletions, LOH, and loss of function (LOF) mutations have been associated with ''TP53''. These alterations often confer a poor prognosis and chemoresistance.

==Most common types of alterations observed in TP53==

==Most common types of alterations observed in TP53==