Changes

<blockquote class='blockedit'>{{Box-round|title=v4:Clinical Features|The content below was from the old template. Please incorporate above.}}

<blockquote class='blockedit'>{{Box-round|title=v4:Clinical Features|The content below was from the old template. Please incorporate above.}}</blockquote>

<blockquote class='blockedit'>{{Box-round|title=Unassigned References|The following referenees were placed in the header. Please place them into the appropriate locations in the text.}}<ref>Arber, D.A., et al., ''Hematopathology''. 2017, Philadelphia, PA: Elsevier.</ref></blockquote>

<blockquote class='blockedit'>{{Box-round|title=Unassigned References|The following referenees were placed in the header. Please place them into the appropriate locations in the text.}}</blockquote><ref>Arber, D.A., et al., ''Hematopathology''. 2017, Philadelphia, PA: Elsevier.</ref><blockquote class="blockedit">

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==Sites of Involvement==

==Sites of Involvement==

<blockquote class='blockedit'>{{Box-round|title=v4:Chromosomal Rearrangements (Gene Fusions)|The content below was from the old template. Please incorporate above.}}

<blockquote class='blockedit'>{{Box-round|title=v4:Chromosomal Rearrangements (Gene Fusions)|The content below was from the old template. Please incorporate above.}}</blockquote>

<blockquote class='blockedit'>{{Box-round|title=Unassigned References|The following referenees were placed in the header. Please place them into the appropriate locations in the text.}}<ref>{{Cite journal|last=Martín-Garcia|first=David|last2=Navarro|first2=Alba|last3=Valdés-Mas|first3=Rafael|last4=Clot|first4=Guillem|last5=Gutiérrez-Abril|first5=Jesús|last6=Prieto|first6=Miriam|last7=Ribera-Cortada|first7=Inmaculada|last8=Woroniecka|first8=Renata|last9=Rymkiewicz|first9=Grzegorz|date=02 28, 2019|title=CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma|url=https://pubmed.ncbi.nlm.nih.gov/30538135|journal=Blood|volume=133|issue=9|pages=940–951|doi=10.1182/blood-2018-07-862151|issn=1528-0020|pmc=6396173|pmid=30538135}}</ref></blockquote>

<blockquote class='blockedit'>{{Box-round|title=Unassigned References|The following referenees were placed in the header. Please place them into the appropriate locations in the text.}}</blockquote><ref>{{Cite journal|last=Martín-Garcia|first=David|last2=Navarro|first2=Alba|last3=Valdés-Mas|first3=Rafael|last4=Clot|first4=Guillem|last5=Gutiérrez-Abril|first5=Jesús|last6=Prieto|first6=Miriam|last7=Ribera-Cortada|first7=Inmaculada|last8=Woroniecka|first8=Renata|last9=Rymkiewicz|first9=Grzegorz|date=02 28, 2019|title=CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma|url=https://pubmed.ncbi.nlm.nih.gov/30538135|journal=Blood|volume=133|issue=9|pages=940–951|doi=10.1182/blood-2018-07-862151|issn=1528-0020|pmc=6396173|pmid=30538135}}</ref><blockquote class="blockedit">

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* Individual Region Genomic Gain/Loss/LOH

* Individual Region Genomic Gain/Loss/LOH

* Characteristic Chromosomal Patterns

* Characteristic Chromosomal Patterns

* Gene Mutations (SNV/INDEL)}}

* Gene Mutations (SNV/INDEL)}}</blockquote>

* Median survival: 5 - 7 years

* Median survival: 5 - 7 years

*** High-risk patients based on MIPI-C  

*** High-risk patients based on MIPI-C  

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==Individual Region Genomic Gain / Loss / LOH==

==Individual Region Genomic Gain / Loss / LOH==

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<blockquote class='blockedit'>{{Box-round|title=v4:Genomic Gain/Loss/LOH|The content below was from the old template. Please incorporate above.}}

<blockquote class='blockedit'>{{Box-round|title=v4:Genomic Gain/Loss/LOH|The content below was from the old template. Please incorporate above.}}</blockquote>

Secondary chromosomal aberrations<ref>{{Cite journal|last=C|first=Royo|last2=I|first2=Salaverria|last3=Em|first3=Hartmann|last4=A|first4=Rosenwald|last5=E|first5=Campo|last6=S|first6=Beà|date=2011|title=The complex landscape of genetic alterations in mantle cell lymphoma|url=https://pubmed.ncbi.nlm.nih.gov/21945515/|language=en|pmid=21945515}}</ref>

Secondary chromosomal aberrations<ref>{{Cite journal|last=C|first=Royo|last2=I|first2=Salaverria|last3=Em|first3=Hartmann|last4=A|first4=Rosenwald|last5=E|first5=Campo|last6=S|first6=Beà|date=2011|title=The complex landscape of genetic alterations in mantle cell lymphoma|url=https://pubmed.ncbi.nlm.nih.gov/21945515/|language=en|pmid=21945515}}</ref>

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==Characteristic Chromosomal Patterns==

==Characteristic Chromosomal Patterns==

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<blockquote class='blockedit'>{{Box-round|title=v4:Characteristic Chromosomal Aberrations / Patterns|The content below was from the old template. Please incorporate above.}}

<blockquote class='blockedit'>{{Box-round|title=v4:Characteristic Chromosomal Aberrations / Patterns|The content below was from the old template. Please incorporate above.}}</blockquote>

*''CCND1'' rearrangement; t(11;14)(q13;q32)

*''CCND1'' rearrangement; t(11;14)(q13;q32)

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==Gene Mutations (SNV / INDEL)==

==Gene Mutations (SNV / INDEL)==

<blockquote class='blockedit'>{{Box-round|title=v4:Gene Mutations (SNV/INDEL)|The content below was from the old template. Please incorporate above.}}

<blockquote class='blockedit'>{{Box-round|title=v4:Gene Mutations (SNV/INDEL)|The content below was from the old template. Please incorporate above.}}</blockquote>

<blockquote class='blockedit'>{{Box-round|title=Unassigned References|The following referenees were placed in the header. Please place them into the appropriate locations in the text.}}<ref>{{Cite journal|last=Rosenquist|first=R.|last2=Beà|first2=S.|last3=Du|first3=M.-Q.|last4=Nadel|first4=B.|last5=Pan-Hammarström|first5=Q.|date=11 2017|title=Genetic landscape and deregulated pathways in B-cell lymphoid malignancies|url=https://pubmed.ncbi.nlm.nih.gov/28631441|journal=Journal of Internal Medicine|volume=282|issue=5|pages=371–394|doi=10.1111/joim.12633|issn=1365-2796|pmid=28631441}}</ref></blockquote>

<blockquote class='blockedit'>{{Box-round|title=Unassigned References|The following referenees were placed in the header. Please place them into the appropriate locations in the text.}}</blockquote><ref>{{Cite journal|last=Rosenquist|first=R.|last2=Beà|first2=S.|last3=Du|first3=M.-Q.|last4=Nadel|first4=B.|last5=Pan-Hammarström|first5=Q.|date=11 2017|title=Genetic landscape and deregulated pathways in B-cell lymphoid malignancies|url=https://pubmed.ncbi.nlm.nih.gov/28631441|journal=Journal of Internal Medicine|volume=282|issue=5|pages=371–394|doi=10.1111/joim.12633|issn=1365-2796|pmid=28631441}}</ref><blockquote class="blockedit">

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==Epigenomic Alterations==

==Epigenomic Alterations==

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<blockquote class='blockedit'>{{Box-round|title=v4:Genes and Main Pathways Involved|The content below was from the old template. Please incorporate above.}}

<blockquote class='blockedit'>{{Box-round|title=v4:Genes and Main Pathways Involved|The content below was from the old template. Please incorporate above.}}</blockquote>

Please refer to Gene Mutations (SNV/INDEL)

Please refer to Gene Mutations (SNV/INDEL)

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==Genetic Diagnostic Testing Methods==

==Genetic Diagnostic Testing Methods==