Difference between revisions of "Cancer Types"

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== Common Adult Cancers ==
 
== Common Adult Cancers ==
 +
#[[:Category:AML|Acute Myeloid Leukemia]]
 +
#[[:Category:Kidney|Neoplasms of the Kidney]]
 +
#[[:Category:Brain|Neoplasms of the Brain and CNS]]
 +
 
== Common Pediatric Cancers ==
 
== Common Pediatric Cancers ==
  
 
== WHO Classification of Tumours of the Central Nervous System (2016) ==
 
== WHO Classification of Tumours of the Central Nervous System (2016) ==
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''CNS Tumors'''
 +
<div class="mw-collapsible-content">
  
 
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
Line 277: Line 284:
 
</div>
 
</div>
 
'''Metastatic tumors'''
 
'''Metastatic tumors'''
 +
</div>
 +
</div>
  
−
== WHO Classification of Tumours of the Urinary System and Male Genital Organs (2016) ==  
+
== WHO Classification of Pathology and Genetics of Head and Neck Tumors ==
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Head and Neck Tumors'''
 +
<div class="mw-collapsible-content">
  
−
== WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart (2015) ==
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Nasal cavity and paranasal sinuses'''
 +
<div class="mw-collapsible-content">
 +
: Malignant epithelial tumours
 +
: [[Squamous cell carcinoma]]
 +
: [[Lymphoepithelial carcinoma]]
 +
: [[Sinonasal undifferentiated carcinoma]]
 +
: [[Adenocarcinoma]]
 +
: [[Salivary gland-type carcinomas]]
 +
: [[Neuroendocrine tumours]]
 +
: [[Benign epithelial tumours]]
 +
: [[Schneiderian papillomas]]
 +
: [[Respiratory epithelial adenomatoid hamartoma]]
 +
: [[Salivary gland-type adenomas]]
 +
: [[Soft tissue tumours]]
 +
: [[Malignant soft tissue tumours]]
 +
: [[Borderline and LMP tumours]]
 +
: [[Benign soft tissue tumours]]
 +
: [[Tumours of bone and cartilage]]
 +
: [[Malignant tumours]]
 +
: [[Benign tumours]]
 +
: [[Haematolymphoid tumours]]
 +
: [[Neuroectodermal tumours]]
 +
: [[Germ cell tumours]]
 +
: [[Secondary tumours]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Nasopharynx'''
 +
<div class="mw-collapsible-content">
 +
: Malignant epithelial tumours
 +
: Nasopharyngeal carcinoma
 +
: Papillary adenocarcinoma
 +
: Salivary gland-type carcinomas
 +
: Benign epithelial tumours
 +
: Nasopharyngeal angiofibroma
 +
: Haematolymphoid tumours
 +
: Tumours of bone and cartilage
 +
: Secondary tumours
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Hypopharynx, larynx and trachea'''
 +
<div class="mw-collapsible-content">
 +
: Malignant epithelial tumours
 +
: Squamous cell carcinoma
 +
: Verrucous carcinoma
 +
: Basaloid squamous cell carcinoma
 +
: Papillary squamous cell carcinoma
 +
: Spindle cell carcinoma
 +
: Acantholytic squamous cell carcinoma
 +
: Adenosquamous carcinoma
 +
: Lymphoepithelial carcinoma
 +
: Giant cell carcinoma
 +
: Malignant salivary gland-type tumours
 +
: Neuroendocrine tumours
 +
: Adenocarcinoma, N.O.S.
 +
: Myoepithelial carcinoma
 +
: Carcinoma ex pleomorphic adenoma
 +
: Carcinosarcoma
 +
: Metastasizing pleomorphic adenoma
 +
: Squamous cell carcinoma
 +
: Small cell carcinoma
 +
: Large cell carcinoma
 +
: Lymphoepithelial carcinoma
 +
: Sialoblastoma Benign epithelial tumours
 +
: Pleomorphic adenoma
 +
: Myoepithelioma
 +
: Basal cell adenoma
 +
: Warthin tumour
 +
: Oncocytoma
 +
: Canalicular adenoma
 +
: Sebaceous adenoma
 +
: Lymphadenomas
 +
: Ductal papillomas
 +
: Cystadenoma
 +
: Soft tissue tumours
 +
: Haemangioma
 +
: Haematolymphoid tumours
 +
: Secondary tumours
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Odontogenic tumours'''
 +
<div class="mw-collapsible-content">
 +
: Odontogenic carcinomas
 +
: Ameloblastic carcinomas
 +
: Primary intraosseous squamous cell carcinomas
 +
: Clear cell odontogenic carcinoma
 +
: Ghost cell odontogenic carcinoma
 +
: Odontogenic sarcomas
 +
: Benign tumours
 +
: Odontogenic epithelium with mature fibrous stroma,
 +
: without odontogenic ectomesenchyme
 +
: Ameloblastomas
 +
: Squamous odontogenic tumour
 +
: Calcifying epithelial odontogenic tumour
 +
: Adenomatoid odontogenic tumour
 +
: Keratocystic odontogenic tumour
 +
: Odontogenic epithelium with odontogenic ectome-
 +
: senchyme, with or without tissue formation
 +
: Ameloblastic fibroma / fibrodentinoma
 +
: Ameloblastic fibro-odontoma
 +
: Odontoma, complex type
 +
: Odontoma, compound type
 +
: Odontoameloblastoma
 +
: Calcifying cystic odontogenic tumour
 +
: Dentinogenic ghost cell tumour
 +
: Mesenchyme and/or odontogenic ectome- senchyme, with or without odontogenic epithelium
 +
: Odontogenic fibroma
 +
: Odontogenic myxoma / myxofibroma
 +
: Cementoblastoma
 +
: Epithelial precursor lesions
 +
: Benign epithelial tumours
 +
: Papilloma / papillomatosis
 +
: Benign salivary gland-type tumours
 +
: Malignant soft tissue tumours
 +
: Inflammatory myofibroblastic tumour
 +
: Benign soft tissue tumours
 +
: Haematolymphoid tumours
 +
: Tumours of bone and cartilage
 +
: Mucosal malignant melanoma
 +
: Secondary tumours
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Oral cavity and oropharynx'''
 +
<div class="mw-collapsible-content">
 +
: Malignant epithelial tumours
 +
: Squamous cell carcinoma
 +
: Lymphoepithelial carcinoma
 +
: Epithelial precursor lesions
 +
: Proliferative verrucous leukoplakia
 +
: Precancerous conditions
 +
: Benign epithelial tumours
 +
: Papillomas
 +
: Granular cell tumour
 +
: Keratoacanthoma
 +
: Papillary hyperplasia
 +
: Median rhomboid glossitis
 +
: Salivary gland tumours
 +
: Kaposi sarcoma
 +
: Lymphangioma
 +
: Ectomesenchymal chondromyxoid tumour
 +
: Focal oral mucinosis
 +
: Congenital granular cell epulis
 +
: Haematolymphoid tumours
 +
: Malignant melanoma
 +
: Secondary tumours
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Salivary glands'''
 +
<div class="mw-collapsible-content">
 +
: Malignant epithelial tumours
 +
: Acinic cell carcinoma
 +
: Mucoepidermoid  carcinoma
 +
: Adenoid cyctic carcinoma
 +
: Polymorphous low-grade adenocarcinoma
 +
: Epithelial-myoepithelial carcinoma
 +
: Clear cell carcinoma, N.O.S.
 +
: Basal cell adenocarcinoma
 +
: Malignant sebaceous tumours
 +
: Cystadenocarcinoma
 +
: Low-grade cribriform cystadenocarcinoma
 +
: Mucinous adenocarcinoma
 +
: Oncocytic carcinoma
 +
: Salivary duct carcinoma
 +
: Bone related lesions
 +
: Ossifying fibroma
 +
: Fibrous dysplasia
 +
: Osseous dysplasias
 +
: Central giant cell lesion
 +
: Cherubism
 +
: Aneurysmal bone cyst
 +
: Simple bone cyst
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Ear'''
 +
<div class="mw-collapsible-content">
 +
: External ear
 +
: Tumours of ceruminous glands
 +
: Cylindroma
 +
: Squamous cell carcinoma
 +
: Embryonal rhabdomyosarcoma
 +
: Fibrous dysplasia
 +
: Osteoma and exostosis
 +
: Angiolymphoid hyperplasia with eosinophilia
 +
: Kimura disease
 +
: Idiopathic pseudocystic chondromalacia
 +
: Chondrodermatits nodularis chronica helicis
 +
: Middle ear
 +
: Cholesterol granuloma and cholesteatoma
 +
: Adenoma
 +
: Papillary tumours
 +
: Choristoma
 +
: Squamous cell carcinoma
 +
: Meningioma
 +
: Inner ear
 +
: Vesticular schwannoma
 +
: Neurofibromatosis type 2
 +
: Lipoma of the internal auditory canal
 +
: Haemangioma
 +
: Endolymphatic sac tumour
 +
: Haematolymphoid tumours
 +
: Langerhans cell histiocytosis
 +
: Secondary tumours
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Paraganglionic system'''
 +
<div class="mw-collapsible-content">
 +
: Carotid body paraganglioma
 +
: Jugulotympanic  paraganglioma
 +
: Vagal paraganglioma
 +
: Laryngeal paraganglioma
 +
</div>
 +
</div>
 +
</div>
 +
</div>
  
−
== WHO Classification of Tumours of Female Reproductive Organs (2014) ==
+
== WHO Classification of Tumors of the Urinary System and Male Genital Organs (2016) ==
  
−
== WHO Classification of Tumours of Soft Tissue and Bone (2013) ==
+
== WHO Classification of Tumors of Endocrine Organs ==
  
−
== WHO Classification of Tumours of the Breast (2012) ==
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Endocrine Tumors'''
 +
<div class="mw-collapsible-content">
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Tumors of the pituitary'''
 +
<div class="mw-collapsible-content">
 +
:Pituitary adenomas
 +
:Growth hormone producing adenoma
 +
:Prolactin producing adenoma
 +
:Thyrotropin producing adenoma
 +
:ACTH producing adenoma
 +
:Gonadotropin producing adenoma
 +
:Null cell adenoma
 +
:Plurihormonal adenoma
 +
:Pituitary carcinoma
 +
:Gangliocytoma
 +
:Mesenchymal tumors
 +
:Chordoma
 +
:Meningioma
 +
:Granular cell tumour
 +
:Secondary tumors
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Tumors of the thyroid and parathyroid'''
 +
<div class="mw-collapsible-content">
 +
:Papillary carcinoma
 +
:Follicular carcinoma
 +
:Poorly differentiated carcinoma
 +
:Undifferentiated (anaplastic) carcinoma
 +
:Squamous cell carcinoma
 +
:Mucoepidermoid carcinoma
 +
:Sclerosing mucoepidermoid carcinomawith eosinophilia
 +
:Mucinous carcinoma
 +
:Medullary thyroid carcinoma
 +
:Mixed medullary and follicular cell carcinoma
 +
:Spindle cell tumour with thymus-like differentiation
 +
:Carcinoma showing thymus-like differentiation
 +
:Follicular adenoma
 +
:Hyalinizing trabecular tumour
 +
:Teratoma
 +
:Primary lymphoma and plasmacytoma
 +
:Ectopic thymoma
 +
:Angiosarcoma
 +
:Smooth muscle tumors
 +
:Peripheral nerve sheath tumors
 +
:Paraganglioma
 +
:Solitary fibrous tumour
 +
:Rosai-Dorfman disease
 +
:Follicular dendritic cell tumour
 +
:Langerhans cell histiocytosis
 +
:Secondary tumors of the thyroid
 +
:Parathyroid carcinoma
 +
:Parathyroid adenoma
 +
:Secondary tumors of the parathyroid
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Tumors of the adrenal gland'''
 +
<div class="mw-collapsible-content">
 +
:Adrenal cortical carcinoma
 +
:Adrenal cortical adenoma
 +
:Malignant adrenal phaeochromocytoma
 +
:Benign phaeochromocytoma
 +
:Composite phaeochromocytoma or paraganglioma
 +
:Extra-adrenal paraganglioma
 +
:Carotid body, jugulotympanic, vagal, laryngeal, aortico-pulmonary
 +
:Gangliocytic, cauda equina, orbital, nasopharyngeal
 +
:Extra-adrenal sympathetic paraganglioma
 +
:Superior and inferior paraaortic
 +
:Cervical, intrathoracic and urinary bladder
 +
:Adenomatoid tumour
 +
:Sex cord-stromal tumour
 +
:Adrenal soft tissue and germ cell tumors
 +
:Secondary tumors
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Tumors of the endocrine pancreas'''
 +
<div class="mw-collapsible-content">
 +
:Insulinoma
 +
:Glucagonoma
 +
:Somatostatinoma
 +
:Gastrinoma
 +
:VIPoma
 +
:Serotonin secreting tumour
 +
:ACTH and other ectopic hormone producing tumors
 +
:Non-functioning tumors and microadenomas
 +
:Mixed exocrine-endocrine carcinomas
 +
:Poorly differentiated endocrine carcinoma
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Inherited tumour syndromes'''
 +
<div class="mw-collapsible-content">
 +
:Multiple endocrine neoplasia type 2
 +
:Multiple endocrine neoplasia type 1
 +
:Hyperparathyroidism-Jaw tumour syndrome
 +
:Von Hippel-Lindau syndrome (VHL)
 +
:Familial paraganglioma-phaeochromocytoma syndromes caused by SDHB, SDHC and SDHD mutations
 +
:Neurofibromatosis type 1
 +
:Carney complex
 +
:McCune-Albright syndrome
 +
:Familial non-medullary thyroid cancer
 +
</div>
 +
</div>
 +
</div>
 +
</div>
 +
 
 +
== WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart (2015) ==
 +
 
 +
== WHO Classification of Tumors of Female Reproductive Organs (2014) ==
 +
 
 +
== WHO Classification of Tumors of Soft Tissue and Bone (2013) ==
 +
 
 +
== WHO Classification of Tumors of the Breast (2012) ==
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Breast Tumors'''
 +
<div class="mw-collapsible-content">
 +
'''Invasive carcinoma of no special type (invasive ductal carcinoma)'''
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Special subtypes'''
 +
<div class="mw-collapsible-content">
 +
: [[Invasive lobular carcinoma]]
 +
: [[Tubular carcinoma]] and [[cribriform carcinoma]]
 +
: [[Carcinoma with medullary features]]
 +
: [[Metaplastic carcinoma]]
 +
: [[Carcinoma with apocrine differentiation]]
 +
: [[Salivary gland/skin adnexal type tumors]]
 +
: [[Adenoid cystic carcinoma]]
 +
: [[Mucoepidermoid  carcinoma]]
 +
: [[Polymorphous carcinoma]]
 +
: [[Mucinous carcinoma]] and [[Carcinoma with signet-ring-cell differentiation]]
 +
:      [[Carcinoma with neuroendocrine features]]
 +
: [[Invasive papillary carcinoma]]
 +
: [[Invasive micropapillary carcinoma]]
 +
: [[Inflammatory carcinoma]]
 +
: Bilateral breast carcinoma and non-synchronous breast carcinoma
 +
: [[Secretory carcinoma]]
 +
: [[Oncocytic carcinoma]]
 +
: [[Sebaceous carcinoma]]
 +
: [[Lipid-rich carcinoma]]
 +
: [[Glycogen-rich clear cell carcinoma]]
 +
: [[Acinic cell carcinoma]]
 +
</div>
 +
</div>
 +
 
 +
'''Lobular neoplasia'''
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Intraductal proliferative lesions'''
 +
<div class="mw-collapsible-content">
 +
: Usual ductal hyperplasia
 +
: Columnar cell lesions
 +
: Atypical ductal hyperplasia
 +
: [[Ductal carcinoma in situ]]
 +
</div>
 +
</div>
 +
 
 +
'''Microinvasive carcinoma'''
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Intraductal papillary lesions'''
 +
<div class="mw-collapsible-content">
 +
: [[Intraductal papilloma]]
 +
: [[Intraductal papillary carcinoma]]
 +
: [[Encapsulated papillary carcinoma]]
 +
: [[Solid papillary carcinoma]]
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Benign epithelial proliferations'''
 +
<div class="mw-collapsible-content">
 +
: Adenosis, sclerosing adenosis and apocrine adenosis
 +
: [[Microglandular adenosis]],[[atypical microglandular adenosis and microglandular adenosis with carcinoma]]
 +
: [[Radial scar and complex sclerosing lesion]]           
 +
: [[Tubular adenoma]]
 +
: Lactating adenoma
 +
: Apocrine adenoma 
 +
: Ductal adenoma 
 +
: Pleomorphic adenoma
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Myoepithelial and epithelial–myoepithelial lesions'''
 +
<div class="mw-collapsible-content">
 +
: [[Myoepithelial and epithelial–myoepithelial lesions]]
 +
: [[Adenomyoepithelioma and adenomyoepithelioma with carcinoma]]
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Mesenchymal tumors'''
 +
<div class="mw-collapsible-content">
 +
: Nodular fasciitis
 +
: Benign vascular lesions
 +
: [[Pseudoangiomatous stromal hyperplasia]]
 +
: [[Myofibroblastoma]]
 +
: [[Desmoid-type fibromatosis]]
 +
: Inflammatory myofibroblastic tumour
 +
: Lipoma
 +
: Granular cell tumour and benign peripheral
 +
: nerve-sheath tumour
 +
: [[Angiosarcoma]]
 +
: Liposarcoma
 +
: Rhabdomyosarcoma
 +
: Osteosarcoma
 +
: Leiomyoma and leiomyosarcoma
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Fibroepithelial tumors'''
 +
<div class="mw-collapsible-content">
 +
: [[Fibroadenoma]]
 +
: [[Phyllodes tumour]]
 +
: Hamartoma
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Tumors of the nipple'''
 +
<div class="mw-collapsible-content">
 +
: Nipple adenoma
 +
: Syringomatous tumour
 +
: [[Paget disease]]
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Lymphoid and haematopoietic tumors'''
 +
<div class="mw-collapsible-content">
 +
: [[Diffuse large B-cell lymphoma]]
 +
: Burkitt lymphoma
 +
: T-cell lymphoma
 +
: Extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue
 +
: Follicular lymphoma
 +
</div>
 +
</div>
 +
 +
'''Metastases of extramammary malignancies to the breast'''
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Tumors of the male breast'''
 +
<div class="mw-collapsible-content">
 +
: [[Gynaecomastia]]
 +
: [[Carcinoma of the male breast]]
 +
</div>
 +
</div>
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Genetic susceptibility: inherited syndromes'''
 +
<div class="mw-collapsible-content">
 +
: Inherited syndromes associated with an increased risk of breast cancer: Introduction
 +
: [[BRCA1 symdrome]] and [[BRCA2 syndrome]]
 +
: [[Li-Fraumeni syndrome]]
 +
: Ataxia telangiectasia syndrome
 +
: Cowden syndrome
 +
: Lynch syndrome
 +
: Other breast cancer-predisposing genes
 +
</div>
 +
</div>
 +
</div>
 +
</div>
  
 
== WHO Classification of Tumours of the Digestive System (2010) ==
 
== WHO Classification of Tumours of the Digestive System (2010) ==
  
−
== WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (2008) ==  
+
== WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (2008) ==
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Hematological and Lymphoid Neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
 
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Myeloproliferative neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Chronic myelogenous leukaemia, BCR-ABL1 positive]]
 +
:[[Chronic neutrophilic leukaemia]]
 +
:[[Polycythaemia vera]]
 +
:[[Primary myelofibrosis]]
 +
:[[Essential thrombocythaemia]]
 +
:[[Chronic eosinophilic leukaemia, NOS]]
 +
:[[HAEM4:Mastocytosis]]
 +
:[[Cutaneous mastocytosis]]
 +
:[[Systemic mastocytosis]]
 +
:[[Mast cell leukaemia]]
 +
:[[Mast cell sarcoma]]
 +
:[[Extracutaneous mastocytoma]]
 +
:[[Myeloproliferative neoplasm, unclassifiable]]
 +
</div>
 +
</div>
 +
'''[[Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA,PDGFRB or FGFR1]]
 +
'''
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Myelodysplastic/myeloproliferative neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Chronic myelomonocytic leukaemia]]
 +
:[[Atypical chronic myeloid leukaemia, BCR-ABL1 negative]]
 +
:[[Juvenile myelomonocytic leukaemia]]
 +
:[[Myelodysplastic/myeloproliferative neoplasm, unclassifiable]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Myelodysplastic syndromes]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Myelodysplastic syndromes/neoplasms, overview]]
 +
:[[Refractory cytopenia with unilineage dysplasia]]
 +
:[[Refractory anaemia with ring sideroblasts]]
 +
:[[Refractory cytopenia with multilineage dysplasia]]
 +
:[[Refractory anaemia with excess blasts]]
 +
:[[Myelodysplastic syndrome with isolated del(5q)]]
 +
:[[Myelodysplastic syndrome, unclassifiable]]
 +
:[[Childhood myelodysplastic syndrome]]
 +
:[[Refractory cytopenia of childhood]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Acute myeloid leukaemia (AML) and related precursor neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[AML with recurrent genetic abnormalities]]
 +
:[[AML with t(8;21)(q22;q22); RUNX1-RUNX1T1]]
 +
:[[AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11]]
 +
:[[Acute promyelocytic leukaemia with t(15;17)(q22;q12); PML-RARA]]
 +
:[[AML with t(9;11)(p22;q23); MLLT3-MLL]]
 +
:[[AML with t(6;9)(p23;q34); DEK-NUP214]]
 +
:[[AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2);RPN1-EVI1]]
 +
:[[AML (megakaryoblastic) with t(1;22)(p13;q13);RBM15-MKL1]]
 +
:[[AML with mutated NPM1]]
 +
:[[AML with mutated CEBPA]]
 +
:[[AML with myelodysplasia-related changes]]
 +
:[[Therapy-related myeloid neoplasms]]
 +
:[[Acute myeloid leukaemia, NOS]]
 +
:[[AML with minimal differentiation]]
 +
:[[AML without maturation]]
 +
:[[AML with maturation]]
 +
:[[Acute myelomonocytic leukaemia]]
 +
:[[Acute monoblastic and monocytic leukaemia]]
 +
:[[Acute erythroid leukaemia]]
 +
:[[Acute megakaryoblastic leukaemia]]
 +
:[[Acute basophilic leukaemia]]
 +
:[[Acute panmyelosis with myelofibrosis]]
 +
:[[Myeloid sarcoma]]
 +
:[[Myeloid proliferations related to Down syndrome]]
 +
:[[Transient abnormal myelopoiesis]]
 +
:[[Myeloid leukaemia associated with Down syndrome]]
 +
:[[Blastic plasmacytoid dendritic cell neoplasm]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Acute leukaemias of ambiguous lineage]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Acute undifferentiated leukaemia]]
 +
:[[Mixed phenotype acute leukaemia with t(9;22)(q34;q11.2); BCR-ABL1]]
 +
:[[Mixed phenotype acute leukaemia with t(v;11q23); MLL rearranged]]
 +
:[[Mixed phenotype acute leukaemia, B/myeloid, NOS]] 152
 +
:[[Mixed phenotype acute leukaemia, T/myeloid, NOS]] 153
 +
:[[Mixed phenotype acute leukaemia, NOS - rare types]]
 +
:[[Other ambiguous lineage leukaemias]]
 +
:[[Natural killer (NK)-cell lymphoblastic leukaemia/lymphoma]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Precursor lymphoid neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[B lymphoblastic leukaemia/lymphoma, NOS]]
 +
:[[B lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities]]
 +
:[[B lymphoblastic leukaemia/lymphoma with t(9:22)(q34;q11.2); BCR-ABL1]]
 +
:[[B lymphoblastic leukaemia/lymphoma with t(v;11q23); MLL rearranged]]
 +
:[[B lymphoblastic leukaemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1)]]
 +
:[[B lymphoblastic leukaemia/lymphoma with hyperdiploidy]]
 +
:[[B lymphoblastic leukaemia/lymphoma with hypodiploidy (Hypodiploid ALL)]]
 +
:[[B lymphoblastic leukaemia/lymphoma with t(5;14)(q31;q32); IL3-IGH]]
 +
:[[B lymphoblastic leukaemia/lymphoma with t(1;19) (q23;p13.3); E2A-PBX1(TCF3-PBX1)]]
 +
:[[T lymphoblastic leukaemia/lymphoma]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Mature B-cell neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Chronic lymphocytic leukaemia /small lymphocytic lymphoma]]
 +
:[[B-cell prolymphocytic leukaemia]]
 +
:[[Splenic marginal zone lymphoma]]
 +
:[[Hairy cell leukaemia]]
 +
:[[Splenic B-cell lymphoma/leukaemia, unclassifiable]]
 +
:[[Splenic diffuse red pulp small B-cell lymphoma]]
 +
:[[Hairy cell leukaemia-variant]]
 +
:[[Lymphoplasmacytic lymphoma]]
 +
:[[Heavy chain diseases]]
 +
:[[Gamma heavy chain disease]]
 +
:[[Mu heavy chain disease]]
 +
:[[Alpha heavy chain disease]]
 +
:[[Plasma cell neoplasms]]
 +
:[[Monoclonal gammopathy of undetermined significance (MGUS)]]
 +
:[[Plasma cell myeloma]]
 +
:[[Solitary plasmacytoma of bone]]
 +
:[[Extraosseous plasmacytoma]]
 +
:[[Monoclonal immunoglobulin deposition diseases]]
 +
:[[Extranodal marginal zone lymphoma of mucosa- associated lymphoid tissue (MALT lymphoma)]]
 +
:[[Nodal marginal zone lymphoma]]
 +
:[[Follicular lymphoma]]
 +
:[[Primary cutaneous follicle centre lymphoma]]
 +
:[[Mantle cell lymphoma]]
 +
:[[Diffuse large B-cell lymphoma (DLBCL), NOS]]
 +
:[[T cell/histiocyte-rich large B-cell lymphoma]]
 +
:[[Primary DLBCL of the CNS]]
 +
:[[Primary cutaneous DLBCL, leg type]]
 +
:[[EBV positive DLBCL of the elderly]]
 +
:[[DLBCL associated with chronic inflammation]]
 +
:[[Lymphomatoid granulomatosis]]
 +
:[[Primary mediastinal (thymic) large B-cell lymphoma]]
 +
:[[Intravascular large B-cell lymphoma]]
 +
:[[ALK positive large B-cell lymphoma]]
 +
:[[Plasmablastic lymphoma]]
 +
:[[Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease]]
 +
:[[Primary effusion lymphoma]]
 +
:[[Burkitt lymphoma]]
 +
:[[B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and Burkitt lymphoma]]
 +
:[[B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and classical Hodgkin lymphoma]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Mature T- and NK-cell neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[T-cell prolymphocytic leukaemia]]
 +
:[[T-cell large granular lymphocytic leukaemia]]
 +
:[[Chronic lymphoproliferative disorder of NK cells]]
 +
:[[Aggressive NK cell leukaemia]]
 +
:[[Epstein-Barr virus (EBV) positive T-cell lymphoproliferative diseases of childhood]]
 +
:[[Systemic EBV+ T-cell lymphoproliferative disease of childhood]]
 +
:[[Hydroa vacciniforme-like lymphoma]]
 +
:[[Adult T-cell leukaemia/lymphoma]]
 +
:[[Extranodal NK/T-cell lymphoma, nasal type]]
 +
:[[Enteropathy-associated T-cell lymphoma]]
 +
:[[Hepatosplenic T-cell lymphoma]]
 +
:[[Subcutaneous panniculitis-like T-cell lymphoma]]
 +
:[[Mycosis fungoides]]
 +
:[[Sézary syndrome]]
 +
:[[Primary cutaneous CD30 positive T-cell lymphoproliferative disorders]]
 +
:[[Primary cutaneous peripheral T-cell lymphomas, rare subtypes]]
 +
:[[Primary cutaneous gamma-delta T-cell lymphoma]]
 +
:[[Primary cutaneous CD8 positive aggressive epidermotropic cytotoxic T-cell lymphoma]]
 +
:[[Primary cutaneous CD4 positive small/medium T-cell lymphoma]]
 +
:[[Peripheral T-cell lymphoma, NOS]]
 +
:[[Angioimmunoblastic T-cell lymphoma]]
 +
:[[Anaplastic large cell lymphoma, ALK positive]]
 +
:[[Anaplastic large cell lymphoma, ALK negative]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Hodgkin lymphoma]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Nodular lymphocyte predominant Hodgkin lymphoma]]
 +
:[[Classical Hodgkin lymphoma]]
 +
:[[Nodular sclerosis classical Hodgkin lymphoma]]
 +
:[[Mixed cellularity classical Hodgkin lymphoma]]
 +
:[[Lymphocyte-rich classical Hodgkin lymphoma]]
 +
:[[Lymphocyte-depleted classical Hodgkin lymphoma]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Immunodeficiency-associated lymphoproliferative disorders]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Lymphoproliferative diseases associated with primary immune disorders]]
 +
:[[Lymphomas associated with HIV infection]]
 +
:[[Post-transplant lymphoproliferative disorders (PTLD)]]
 +
:[[Plasmacytic hyperplasia and infectious- mononucleosis-like PTLD]]
 +
:[[Polymorphic PTLD]]
 +
:[[Monomorphic PTLD]]
 +
:[[Classical Hodgkin lymphoma type PTLD]]
 +
:[[Other iatrogenic immunodeficiency-associated lymphoproliferative disorders]]
 +
</div>
 +
</div>
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''[[Histiocytic and dendritic cell neoplasms]]'''
 +
<div class="mw-collapsible-content">
 +
:[[Histiocytic sarcoma]]
 +
:[[Tumours derived from Langerhans cells]]
 +
:[[Langerhans cell histiocytosis]]
 +
:[[Langerhans cell sarcoma]]
 +
:[[Interdigitating dendritic cell sarcoma]]
 +
:[[Follicular dendritic cell sarcoma]]
 +
:[[Other rare dendritic cell tumours]]
 +
:[[Disseminated juvenile xanthogranuloma]]
 +
</div>
 +
</div>
 +
</div>
 +
</div>
  
 
== Miscellaneous Cancer Types ==
 
== Miscellaneous Cancer Types ==
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:800px">
 +
'''Miscellaneous Tumors'''
 +
<div class="mw-collapsible-content">
 
: [[Acute Lymphoblastic Leukaemia (ALL)]]
 
: [[Acute Lymphoblastic Leukaemia (ALL)]]
 
: [[Acute Myeloid Leukaemia (AML)]]
 
: [[Acute Myeloid Leukaemia (AML)]]
−
::[[Acute Megakaryoblastic Leukemia (AMKL)]]
+
::[[HAEM5:Acute megakaryoblastic leukaemia]]
 
: [[Adrenal cortical carcinoma]]
 
: [[Adrenal cortical carcinoma]]
 
: [[Anal Cancer]]
 
: [[Anal Cancer]]
Line 491: Line 1,215:
 
: [[Vaginal Cancer]]
 
: [[Vaginal Cancer]]
 
: [[Vulval Cancer]]
 
: [[Vulval Cancer]]
 +
</div>
 +
</div>

Latest revision as of 13:56, 12 December 2023

These classifications are based on WHO/IARC guidelines. See [1] for further details.

Common Adult Cancers

  1. Acute Myeloid Leukemia
  2. Neoplasms of the Kidney
  3. Neoplasms of the Brain and CNS

Common Pediatric Cancers

WHO Classification of Tumours of the Central Nervous System (2016)

CNS Tumors

Diffuse astrocytic and oligodendroglial tumors

Diffuse astrocytoma, IDH-mutant
Gemistocytic astrocytoma, IDH-mutant
Diffuse astrocytoma, IDH-wildtype
Diffuse astrocytoma, NOS
Anaplastic astrocytoma, IDH-mutant
Anaplastic astrocytoma, IDH-wildtype
Anaplastic astrocytoma, NOS
Glioblastoma, IDH-wildtype
Giant cell glioblastoma
Gliosarcoma
Epithelioid glioblastoma
Glioblastoma, IDH-mutant
Glioblastoma, NOS
Diffuse midline glioma, H3 K27M–mutant
Oligodendroglioma, IDH-mutant and 1p/19q-codeleted
Oligodendroglioma, NOS 69
Anaplastic oligodendroglioma, IDH-mutant and 1p/19q-codeleted
Anaplastic oligodendroglioma, NOS
Oligoastrocytoma, NOS
Anaplastic oligoastrocytoma, NOS

Other astrocytic tumors

Pilocytic astrocytoma
Pilomyxoid astrocytoma
Subependymal giant cell astrocytoma
Pleomorphic xanthoastrocytoma
Anaplastic pleomorphic xanthoastrocytoma

Ependymal tumors

Subependymoma
Myxopapillary ependymoma
Ependymoma
Papillary ependymoma
Clear cell ependymoma
Tanycytic ependymoma
Ependymoma, RELA fusion–positive
Anaplastic ependymoma

Other gliomas

Chordoid glioma of the third ventricle
Angiocentric glioma
Astroblastoma

Choroid plexus tumors

Choroid plexus papilloma
Atypical choroid plexus papilloma
Choroid plexus carcinoma

Neuronal and mixed neuronal–glial tumors

Dysembryoplastic neuroepithelial tumour
Gangliocytoma
Ganglioglioma
Anaplastic ganglioglioma
Dysplastic cerebellar gangliocytoma (Lhermitte–Duclos disease)
Desmoplastic infantile astrocytoma and ganglioglioma
Papillary glioneuronal tumour
Rosette-forming glioneuronal tumour
Diffuse leptomeningeal glioneuronal tumour
Central neurocytoma
Extraventricular neurocytoma
Cerebellar liponeurocytoma
Paraganglioma

Tumors of the pineal region

Pineocytoma
Pineal parenchymal tumour of intermediate differentiation
Pineoblastoma
Papillary tumour of the pineal region

Embryonal tumors

Medulloblastoma
Medulloblastoma, NOS
Medulloblastomas, genetically defined
Medulloblastoma, WNT-activated
Medulloblastoma, SHH-activated and TP53-mutant
Medulloblastoma, SHH-activated and TP53-wildtype
Medulloblastoma, non-WNT/non-SHH
Medulloblastomas, histologically defined
Medulloblastoma, classic
Desmoplastic/nodular medulloblastoma
Medulloblastoma with extensive nodularity
Large cell / anaplastic medulloblastoma
Embryonal tumour with multilayered rosettes, C19MC-altered
Embryonal tumour with multilayered rosettes, NOS
Other CNS embryonal tumors
Medulloepithelioma
CNS neuroblastoma
CNS ganglioneuroblastoma
CNS embryonal tumour, NOS
Atypical teratoid/rhabdoid tumour
CNS embryonal tumour with rhabdoid features

Tumors of the cranial and paraspinal nerves

Schwannoma
Cellular schwannoma
Plexiform schwannoma
Melanotic schwannoma
Neurofibroma
Atypical neurofibroma
Plexiform neurofibroma
Perineurioma
Hybrid nerve sheath tumors
Malignant peripheral nerve sheath tumour (MPNST)
MPNST with divergent differentiation
Epithelioid MPNST
MPNST with perineurial differentiation

Meningiomas

Meningioma
Meningioma variants
Meningothelial meningioma
Fibrous meningioma
Transitional meningioma
Psammomatous meningioma
Angiomatous meningioma
Microcystic meningioma
Secretory meningioma
Lymphoplasmacyte-rich meningioma
Metaplastic meningioma
Chordoid meningioma
Clear cell meningioma
Atypical meningioma
Papillary meningioma
Rhabdoid meningioma
Anaplastic (malignant) meningioma

Mesenchymal, non-meningothelial tumors

Solitary fibrous tumour / haemangiopericytoma
Haemangioblastoma
Haemangioma
Epithelioid haemangioendothelioma
Angiosarcoma
Kaposi sarcoma
Ewing sarcoma / peripheral primitive
Neuroectodermal tumour
Lipoma
Angiolipoma
Hibernoma
Liposarcoma
Desmoid-type fibromatosis
Myofibroblastoma
Inflammatory myofibroblastic tumour
Benign fibrous histiocytoma
Fibrosarcoma
Undifferentiated pleomorphic sarcoma / malignant
Fibrous histiocytoma
Leiomyoma
Leiomyosarcoma
Rhabdomyoma
Rhabdomyosarcoma
Chondroma
Chondrosarcoma
Osteoma
Osteochondroma
Osteosarcoma

Melanocytic tumors

Meningeal melanocytosis
Meningeal melanomatosis
Meningeal melanocytoma
Meningeal melanoma

Lymphomas

Diffuse large B-cell lymphoma of the CNS
Corticoid-mitigated lymphoma
Sentinel lesions
Immunodeficiency-associated CNS lymphomas
AIDS-related diffuse large B-cell lymphoma
EBV+ diffuse large B-cell lymphoma, NOS
Lymphomatoid granulomatosis
Intravascular large B-cell lymphoma
Miscellaneous rare lymphomas in the CNS
Low-grade B-cell lymphomas
T-cell and NK/T-cell lymphomas
Anaplastic large cell lymphoma (ALK+/ALK–)
MALT lymphoma of the dura

Histiocytic tumors

Langerhans cell histiocytosis
Erdheim–Chester disease
Rosai–Dorfman disease
Juvenile xanthogranuloma
Histiocytic sarcoma

Germ cell tumors

Germinoma
Embryonal carcinoma
Yolk sac tumour
Choriocarcinoma
Teratoma
Mature teratoma
Immature teratoma
Teratoma with malignant transformation
Mixed germ cell tumour

Familial tumour syndromes

Neurofibromatosis type 1
Neurofibromatosis type 2
Schwannomatosis
Von Hippel–Lindau disease
Tuberous sclerosis
Li–Fraumeni syndrome
Cowden syndrome
Turcot syndrome
Mismatch repair cancer syndrome
Familial adenomatous polyposis
Naevoid basal cell carcinoma syndrome
Rhabdoid tumour predisposition syndrome

Tumors of the sellar region

Craniopharyngioma
Adamantinomatous craniopharyngioma
Papillary craniopharyngioma

Granular cell tumour of the sellar region Pituicytoma 332 Spindle cell oncocytoma

Metastatic tumors

WHO Classification of Pathology and Genetics of Head and Neck Tumors

Head and Neck Tumors

Nasal cavity and paranasal sinuses

Malignant epithelial tumours
Squamous cell carcinoma
Lymphoepithelial carcinoma
Sinonasal undifferentiated carcinoma
Adenocarcinoma
Salivary gland-type carcinomas
Neuroendocrine tumours
Benign epithelial tumours
Schneiderian papillomas
Respiratory epithelial adenomatoid hamartoma
Salivary gland-type adenomas
Soft tissue tumours
Malignant soft tissue tumours
Borderline and LMP tumours
Benign soft tissue tumours
Tumours of bone and cartilage
Malignant tumours
Benign tumours
Haematolymphoid tumours
Neuroectodermal tumours
Germ cell tumours
Secondary tumours

Nasopharynx

Malignant epithelial tumours
Nasopharyngeal carcinoma
Papillary adenocarcinoma
Salivary gland-type carcinomas
Benign epithelial tumours
Nasopharyngeal angiofibroma
Haematolymphoid tumours
Tumours of bone and cartilage
Secondary tumours

Hypopharynx, larynx and trachea

Malignant epithelial tumours
Squamous cell carcinoma
Verrucous carcinoma
Basaloid squamous cell carcinoma
Papillary squamous cell carcinoma
Spindle cell carcinoma
Acantholytic squamous cell carcinoma
Adenosquamous carcinoma
Lymphoepithelial carcinoma
Giant cell carcinoma
Malignant salivary gland-type tumours
Neuroendocrine tumours
Adenocarcinoma, N.O.S.
Myoepithelial carcinoma
Carcinoma ex pleomorphic adenoma
Carcinosarcoma
Metastasizing pleomorphic adenoma
Squamous cell carcinoma
Small cell carcinoma
Large cell carcinoma
Lymphoepithelial carcinoma
Sialoblastoma Benign epithelial tumours
Pleomorphic adenoma
Myoepithelioma
Basal cell adenoma
Warthin tumour
Oncocytoma
Canalicular adenoma
Sebaceous adenoma
Lymphadenomas
Ductal papillomas
Cystadenoma
Soft tissue tumours
Haemangioma
Haematolymphoid tumours
Secondary tumours

Odontogenic tumours

Odontogenic carcinomas
Ameloblastic carcinomas
Primary intraosseous squamous cell carcinomas
Clear cell odontogenic carcinoma
Ghost cell odontogenic carcinoma
Odontogenic sarcomas
Benign tumours
Odontogenic epithelium with mature fibrous stroma,
without odontogenic ectomesenchyme
Ameloblastomas
Squamous odontogenic tumour
Calcifying epithelial odontogenic tumour
Adenomatoid odontogenic tumour
Keratocystic odontogenic tumour
Odontogenic epithelium with odontogenic ectome-
senchyme, with or without tissue formation
Ameloblastic fibroma / fibrodentinoma
Ameloblastic fibro-odontoma
Odontoma, complex type
Odontoma, compound type
Odontoameloblastoma
Calcifying cystic odontogenic tumour
Dentinogenic ghost cell tumour
Mesenchyme and/or odontogenic ectome- senchyme, with or without odontogenic epithelium
Odontogenic fibroma
Odontogenic myxoma / myxofibroma
Cementoblastoma
Epithelial precursor lesions
Benign epithelial tumours
Papilloma / papillomatosis
Benign salivary gland-type tumours
Malignant soft tissue tumours
Inflammatory myofibroblastic tumour
Benign soft tissue tumours
Haematolymphoid tumours
Tumours of bone and cartilage
Mucosal malignant melanoma
Secondary tumours

Oral cavity and oropharynx

Malignant epithelial tumours
Squamous cell carcinoma
Lymphoepithelial carcinoma
Epithelial precursor lesions
Proliferative verrucous leukoplakia
Precancerous conditions
Benign epithelial tumours
Papillomas
Granular cell tumour
Keratoacanthoma
Papillary hyperplasia
Median rhomboid glossitis
Salivary gland tumours
Kaposi sarcoma
Lymphangioma
Ectomesenchymal chondromyxoid tumour
Focal oral mucinosis
Congenital granular cell epulis
Haematolymphoid tumours
Malignant melanoma
Secondary tumours

Salivary glands

Malignant epithelial tumours
Acinic cell carcinoma
Mucoepidermoid carcinoma
Adenoid cyctic carcinoma
Polymorphous low-grade adenocarcinoma
Epithelial-myoepithelial carcinoma
Clear cell carcinoma, N.O.S.
Basal cell adenocarcinoma
Malignant sebaceous tumours
Cystadenocarcinoma
Low-grade cribriform cystadenocarcinoma
Mucinous adenocarcinoma
Oncocytic carcinoma
Salivary duct carcinoma
Bone related lesions
Ossifying fibroma
Fibrous dysplasia
Osseous dysplasias
Central giant cell lesion
Cherubism
Aneurysmal bone cyst
Simple bone cyst

Ear

External ear
Tumours of ceruminous glands
Cylindroma
Squamous cell carcinoma
Embryonal rhabdomyosarcoma
Fibrous dysplasia
Osteoma and exostosis
Angiolymphoid hyperplasia with eosinophilia
Kimura disease
Idiopathic pseudocystic chondromalacia
Chondrodermatits nodularis chronica helicis
Middle ear
Cholesterol granuloma and cholesteatoma
Adenoma
Papillary tumours
Choristoma
Squamous cell carcinoma
Meningioma
Inner ear
Vesticular schwannoma
Neurofibromatosis type 2
Lipoma of the internal auditory canal
Haemangioma
Endolymphatic sac tumour
Haematolymphoid tumours
Langerhans cell histiocytosis
Secondary tumours

Paraganglionic system

Carotid body paraganglioma
Jugulotympanic paraganglioma
Vagal paraganglioma
Laryngeal paraganglioma

WHO Classification of Tumors of the Urinary System and Male Genital Organs (2016)

WHO Classification of Tumors of Endocrine Organs

Endocrine Tumors

Tumors of the pituitary

Pituitary adenomas
Growth hormone producing adenoma
Prolactin producing adenoma
Thyrotropin producing adenoma
ACTH producing adenoma
Gonadotropin producing adenoma
Null cell adenoma
Plurihormonal adenoma
Pituitary carcinoma
Gangliocytoma
Mesenchymal tumors
Chordoma
Meningioma
Granular cell tumour
Secondary tumors

Tumors of the thyroid and parathyroid

Papillary carcinoma
Follicular carcinoma
Poorly differentiated carcinoma
Undifferentiated (anaplastic) carcinoma
Squamous cell carcinoma
Mucoepidermoid carcinoma
Sclerosing mucoepidermoid carcinomawith eosinophilia
Mucinous carcinoma
Medullary thyroid carcinoma
Mixed medullary and follicular cell carcinoma
Spindle cell tumour with thymus-like differentiation
Carcinoma showing thymus-like differentiation
Follicular adenoma
Hyalinizing trabecular tumour
Teratoma
Primary lymphoma and plasmacytoma
Ectopic thymoma
Angiosarcoma
Smooth muscle tumors
Peripheral nerve sheath tumors
Paraganglioma
Solitary fibrous tumour
Rosai-Dorfman disease
Follicular dendritic cell tumour
Langerhans cell histiocytosis
Secondary tumors of the thyroid
Parathyroid carcinoma
Parathyroid adenoma
Secondary tumors of the parathyroid

Tumors of the adrenal gland

Adrenal cortical carcinoma
Adrenal cortical adenoma
Malignant adrenal phaeochromocytoma
Benign phaeochromocytoma
Composite phaeochromocytoma or paraganglioma
Extra-adrenal paraganglioma
Carotid body, jugulotympanic, vagal, laryngeal, aortico-pulmonary
Gangliocytic, cauda equina, orbital, nasopharyngeal
Extra-adrenal sympathetic paraganglioma
Superior and inferior paraaortic
Cervical, intrathoracic and urinary bladder
Adenomatoid tumour
Sex cord-stromal tumour
Adrenal soft tissue and germ cell tumors
Secondary tumors

Tumors of the endocrine pancreas

Insulinoma
Glucagonoma
Somatostatinoma
Gastrinoma
VIPoma
Serotonin secreting tumour
ACTH and other ectopic hormone producing tumors
Non-functioning tumors and microadenomas
Mixed exocrine-endocrine carcinomas
Poorly differentiated endocrine carcinoma

Inherited tumour syndromes

Multiple endocrine neoplasia type 2
Multiple endocrine neoplasia type 1
Hyperparathyroidism-Jaw tumour syndrome
Von Hippel-Lindau syndrome (VHL)
Familial paraganglioma-phaeochromocytoma syndromes caused by SDHB, SDHC and SDHD mutations
Neurofibromatosis type 1
Carney complex
McCune-Albright syndrome
Familial non-medullary thyroid cancer

WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart (2015)

WHO Classification of Tumors of Female Reproductive Organs (2014)

WHO Classification of Tumors of Soft Tissue and Bone (2013)

WHO Classification of Tumors of the Breast (2012)

Breast Tumors

Invasive carcinoma of no special type (invasive ductal carcinoma)

Special subtypes

Invasive lobular carcinoma
Tubular carcinoma and cribriform carcinoma
Carcinoma with medullary features
Metaplastic carcinoma
Carcinoma with apocrine differentiation
Salivary gland/skin adnexal type tumors
Adenoid cystic carcinoma
Mucoepidermoid carcinoma
Polymorphous carcinoma
Mucinous carcinoma and Carcinoma with signet-ring-cell differentiation
Carcinoma with neuroendocrine features
Invasive papillary carcinoma
Invasive micropapillary carcinoma
Inflammatory carcinoma
Bilateral breast carcinoma and non-synchronous breast carcinoma
Secretory carcinoma
Oncocytic carcinoma
Sebaceous carcinoma
Lipid-rich carcinoma
Glycogen-rich clear cell carcinoma
Acinic cell carcinoma

Lobular neoplasia

Intraductal proliferative lesions

Usual ductal hyperplasia
Columnar cell lesions
Atypical ductal hyperplasia
Ductal carcinoma in situ

Microinvasive carcinoma

Intraductal papillary lesions

Intraductal papilloma
Intraductal papillary carcinoma
Encapsulated papillary carcinoma
Solid papillary carcinoma

Benign epithelial proliferations

Adenosis, sclerosing adenosis and apocrine adenosis
Microglandular adenosis,atypical microglandular adenosis and microglandular adenosis with carcinoma
Radial scar and complex sclerosing lesion
Tubular adenoma
Lactating adenoma
Apocrine adenoma
Ductal adenoma
Pleomorphic adenoma

Myoepithelial and epithelial–myoepithelial lesions

Myoepithelial and epithelial–myoepithelial lesions
Adenomyoepithelioma and adenomyoepithelioma with carcinoma

Mesenchymal tumors

Nodular fasciitis
Benign vascular lesions
Pseudoangiomatous stromal hyperplasia
Myofibroblastoma
Desmoid-type fibromatosis
Inflammatory myofibroblastic tumour
Lipoma
Granular cell tumour and benign peripheral
nerve-sheath tumour
Angiosarcoma
Liposarcoma
Rhabdomyosarcoma
Osteosarcoma
Leiomyoma and leiomyosarcoma

Fibroepithelial tumors

Fibroadenoma
Phyllodes tumour
Hamartoma

Tumors of the nipple

Nipple adenoma
Syringomatous tumour
Paget disease

Lymphoid and haematopoietic tumors

Diffuse large B-cell lymphoma
Burkitt lymphoma
T-cell lymphoma
Extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue
Follicular lymphoma

Metastases of extramammary malignancies to the breast

Tumors of the male breast

Gynaecomastia
Carcinoma of the male breast

Genetic susceptibility: inherited syndromes

Inherited syndromes associated with an increased risk of breast cancer: Introduction
BRCA1 symdrome and BRCA2 syndrome
Li-Fraumeni syndrome
Ataxia telangiectasia syndrome
Cowden syndrome
Lynch syndrome
Other breast cancer-predisposing genes

WHO Classification of Tumours of the Digestive System (2010)

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (2008)

Hematological and Lymphoid Neoplasms

Myeloproliferative neoplasms

Chronic myelogenous leukaemia, BCR-ABL1 positive
Chronic neutrophilic leukaemia
Polycythaemia vera
Primary myelofibrosis
Essential thrombocythaemia
Chronic eosinophilic leukaemia, NOS
HAEM4:Mastocytosis
Cutaneous mastocytosis
Systemic mastocytosis
Mast cell leukaemia
Mast cell sarcoma
Extracutaneous mastocytoma
Myeloproliferative neoplasm, unclassifiable

Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA,PDGFRB or FGFR1

Myelodysplastic/myeloproliferative neoplasms

Chronic myelomonocytic leukaemia
Atypical chronic myeloid leukaemia, BCR-ABL1 negative
Juvenile myelomonocytic leukaemia
Myelodysplastic/myeloproliferative neoplasm, unclassifiable

Myelodysplastic syndromes

Myelodysplastic syndromes/neoplasms, overview
Refractory cytopenia with unilineage dysplasia
Refractory anaemia with ring sideroblasts
Refractory cytopenia with multilineage dysplasia
Refractory anaemia with excess blasts
Myelodysplastic syndrome with isolated del(5q)
Myelodysplastic syndrome, unclassifiable
Childhood myelodysplastic syndrome
Refractory cytopenia of childhood

Acute myeloid leukaemia (AML) and related precursor neoplasms

AML with recurrent genetic abnormalities
AML with t(8;21)(q22;q22); RUNX1-RUNX1T1
AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11
Acute promyelocytic leukaemia with t(15;17)(q22;q12); PML-RARA
AML with t(9;11)(p22;q23); MLLT3-MLL
AML with t(6;9)(p23;q34); DEK-NUP214
AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2);RPN1-EVI1
AML (megakaryoblastic) with t(1;22)(p13;q13);RBM15-MKL1
AML with mutated NPM1
AML with mutated CEBPA
AML with myelodysplasia-related changes
Therapy-related myeloid neoplasms
Acute myeloid leukaemia, NOS
AML with minimal differentiation
AML without maturation
AML with maturation
Acute myelomonocytic leukaemia
Acute monoblastic and monocytic leukaemia
Acute erythroid leukaemia
Acute megakaryoblastic leukaemia
Acute basophilic leukaemia
Acute panmyelosis with myelofibrosis
Myeloid sarcoma
Myeloid proliferations related to Down syndrome
Transient abnormal myelopoiesis
Myeloid leukaemia associated with Down syndrome
Blastic plasmacytoid dendritic cell neoplasm

Acute leukaemias of ambiguous lineage

Acute undifferentiated leukaemia
Mixed phenotype acute leukaemia with t(9;22)(q34;q11.2); BCR-ABL1
Mixed phenotype acute leukaemia with t(v;11q23); MLL rearranged
Mixed phenotype acute leukaemia, B/myeloid, NOS 152
Mixed phenotype acute leukaemia, T/myeloid, NOS 153
Mixed phenotype acute leukaemia, NOS - rare types
Other ambiguous lineage leukaemias
Natural killer (NK)-cell lymphoblastic leukaemia/lymphoma

Precursor lymphoid neoplasms

B lymphoblastic leukaemia/lymphoma, NOS
B lymphoblastic leukaemia/lymphoma with recurrent genetic abnormalities
B lymphoblastic leukaemia/lymphoma with t(9:22)(q34;q11.2); BCR-ABL1
B lymphoblastic leukaemia/lymphoma with t(v;11q23); MLL rearranged
B lymphoblastic leukaemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1)
B lymphoblastic leukaemia/lymphoma with hyperdiploidy
B lymphoblastic leukaemia/lymphoma with hypodiploidy (Hypodiploid ALL)
B lymphoblastic leukaemia/lymphoma with t(5;14)(q31;q32); IL3-IGH
B lymphoblastic leukaemia/lymphoma with t(1;19) (q23;p13.3); E2A-PBX1(TCF3-PBX1)
T lymphoblastic leukaemia/lymphoma

Mature B-cell neoplasms

Chronic lymphocytic leukaemia /small lymphocytic lymphoma
B-cell prolymphocytic leukaemia
Splenic marginal zone lymphoma
Hairy cell leukaemia
Splenic B-cell lymphoma/leukaemia, unclassifiable
Splenic diffuse red pulp small B-cell lymphoma
Hairy cell leukaemia-variant
Lymphoplasmacytic lymphoma
Heavy chain diseases
Gamma heavy chain disease
Mu heavy chain disease
Alpha heavy chain disease
Plasma cell neoplasms
Monoclonal gammopathy of undetermined significance (MGUS)
Plasma cell myeloma
Solitary plasmacytoma of bone
Extraosseous plasmacytoma
Monoclonal immunoglobulin deposition diseases
Extranodal marginal zone lymphoma of mucosa- associated lymphoid tissue (MALT lymphoma)
Nodal marginal zone lymphoma
Follicular lymphoma
Primary cutaneous follicle centre lymphoma
Mantle cell lymphoma
Diffuse large B-cell lymphoma (DLBCL), NOS
T cell/histiocyte-rich large B-cell lymphoma
Primary DLBCL of the CNS
Primary cutaneous DLBCL, leg type
EBV positive DLBCL of the elderly
DLBCL associated with chronic inflammation
Lymphomatoid granulomatosis
Primary mediastinal (thymic) large B-cell lymphoma
Intravascular large B-cell lymphoma
ALK positive large B-cell lymphoma
Plasmablastic lymphoma
Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease
Primary effusion lymphoma
Burkitt lymphoma
B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and Burkitt lymphoma
B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and classical Hodgkin lymphoma

Mature T- and NK-cell neoplasms

T-cell prolymphocytic leukaemia
T-cell large granular lymphocytic leukaemia
Chronic lymphoproliferative disorder of NK cells
Aggressive NK cell leukaemia
Epstein-Barr virus (EBV) positive T-cell lymphoproliferative diseases of childhood
Systemic EBV+ T-cell lymphoproliferative disease of childhood
Hydroa vacciniforme-like lymphoma
Adult T-cell leukaemia/lymphoma
Extranodal NK/T-cell lymphoma, nasal type
Enteropathy-associated T-cell lymphoma
Hepatosplenic T-cell lymphoma
Subcutaneous panniculitis-like T-cell lymphoma
Mycosis fungoides
Sézary syndrome
Primary cutaneous CD30 positive T-cell lymphoproliferative disorders
Primary cutaneous peripheral T-cell lymphomas, rare subtypes
Primary cutaneous gamma-delta T-cell lymphoma
Primary cutaneous CD8 positive aggressive epidermotropic cytotoxic T-cell lymphoma
Primary cutaneous CD4 positive small/medium T-cell lymphoma
Peripheral T-cell lymphoma, NOS
Angioimmunoblastic T-cell lymphoma
Anaplastic large cell lymphoma, ALK positive
Anaplastic large cell lymphoma, ALK negative

Hodgkin lymphoma

Nodular lymphocyte predominant Hodgkin lymphoma
Classical Hodgkin lymphoma
Nodular sclerosis classical Hodgkin lymphoma
Mixed cellularity classical Hodgkin lymphoma
Lymphocyte-rich classical Hodgkin lymphoma
Lymphocyte-depleted classical Hodgkin lymphoma

Immunodeficiency-associated lymphoproliferative disorders

Lymphoproliferative diseases associated with primary immune disorders
Lymphomas associated with HIV infection
Post-transplant lymphoproliferative disorders (PTLD)
Plasmacytic hyperplasia and infectious- mononucleosis-like PTLD
Polymorphic PTLD
Monomorphic PTLD
Classical Hodgkin lymphoma type PTLD
Other iatrogenic immunodeficiency-associated lymphoproliferative disorders

Histiocytic and dendritic cell neoplasms

Histiocytic sarcoma
Tumours derived from Langerhans cells
Langerhans cell histiocytosis
Langerhans cell sarcoma
Interdigitating dendritic cell sarcoma
Follicular dendritic cell sarcoma
Other rare dendritic cell tumours
Disseminated juvenile xanthogranuloma

Miscellaneous Cancer Types

Miscellaneous Tumors

Acute Lymphoblastic Leukaemia (ALL)
Acute Myeloid Leukaemia (AML)
HAEM5:Acute megakaryoblastic leukaemia
Adrenal cortical carcinoma
Anal Cancer
Angiomatoid Fibrous Histiocytoma
Bile duct Cancer
Bladder Cancer
Bladder: Squamous cell carcinoma
Bladder: Urothelial carcinomas
Bone Cancer
Adamantinoma
Aneurysmal bone cysts
Angiosarcoma
Chondroblastoma
Chondroma
Chondromyxoid fibroma
Chondrosarcoma
Conventional Osteosarcoma
Dedifferentiated chondrosarcoma
Enchondroma
Epithelioid hemangioendothelioma
Fibrous dysplasia of the bone
Giant cell tumour
Haemangiomas and related lesions
Osteoblastoma
Osteochondroma
Osteoid Osteoma
Osteoma
Osteosarcoma
Periosteal chondroma
Vascular Tumours
Bowel Cancer
Brain tumours
Breast Cancer
Ductal carcinoma
Secretory Ductal Carcinoma
Carcinoid Tumors
Central Nervous System: Glioma
Cervical Cancer
Chordoma
Choriocarcinoma
Chronic lymphocytic leukaemia (CLL)
Chronic myeloid leukaemia (CML)
Clear Cell Hidradenoma of the Skin (CCH)
Colorectal Cancer
Dermatofibrosarcoma Protuberans
Desmoid-type fibromatosis
Digestive organs: Carcinoma of the gallbladder and extrahepatic bile ducts
Digestive organs: Liver: Combined hepatocellular and cholangiocarcinoma
Endometrial Cancer
Esophagus
adenocarcinoma
Barrett's esophagus
Eye Cancer
Eye tumors: an overview
Fallopian tube tumors: an overview
Fibrogenesis imperfecta ossium
Gallbladder Cancer
Gastric Cancer
Gastric Tumors: an overview
Gestational trophoblastic tumours (GTT)
Hairy cell leukaemia
Head and Neck Cancer Squamous cell carcinoma (HNSCC)
Ear: Endolymphatic Sac Tumor (ELST)
Epidermoid carcinoma
Iris Hamartomas
Odontogenic tumor: Ameloblastoma
Oral leukoplakia
Pleomorphic salivary gland adenoma with ins(8)(q12;q11q11) TCEA1/PLAG1
Pleomorphic salivary gland adenoma with inv(8)(q12q12) CHCHD7/PLAG1
Retinoblastoma
Retinoma
Salivary gland tumors: an overview
Thymus
Thymoma
Heart
Cardiac Myxoma
Hodgkin lymphoma
Inflammatory fibroid polyps
Intrahepatic cholangiocarcinoma
Kidney Cancer
Chromophobe renal cell carcinoma
Clear cell renal cell carcinoma
Metanephric adenoma
Mucinous tubular and spindle cell carcinoma
Nephroblastoma (Wilms tumor)
Papillary adenoma
Papillary renal cell carcinoma
Renal cell carcinoma
Renal Oncocytoma
Laryngeal Cancer
Laryngeal squamous cell carcinoma
Liver adenoma
Liver Cancer
Fibrolamellar carcinoma
Hepatoblastoma
Hepatocellular carcinoma
Nested stromal epithelial tumor
Undifferentiated carcinoma
Lung Cancer
Non-small cell carcinoma
Pleuropulmonary blastoma
small cell Cancer
Lymphangioleiomyoma
Lymphangioleiomyomatosis
Lymphoma
Melanoma skin Cancer
Melanoma
Mesothelioma
Molar pregnancy
Mouth and oropharyngeal Cancer
Multiple Myeloma
Nasal and sinus Cancers
Nasopharyngeal Cancer
Nervous system tumours
Peripheral neuroblastic tumours
Neuroblastoma
Ganglioneuroblastoma
Ganglioneuroma
Astrocytic tumors
Ependymomas
Medulloblastoma
Meningioma
Peripheral nerve sheath tumors
Neuroendocrine tumors
Phaeochromocytoma
Neurofibroma
Non Hodgkin lymphoma (NHL)
Oesophageal Cancer
Optic Nerve Glioma
Oral squamous cell carcinoma
Ovarian Cancer
Choriocarcinoma
Epithelial tumors
Germ cell tumors
Sex cord-stromal tumors
Pancreatic Cancer
Penile Cancer
Pericytoma
Pituitary Adenomas
Posterior uveal melanoma
Prostate Cancer
Rectal Cancer
Rhabdoid tumor
Salivary gland Cancer
Warthin's Tumors
Skin Cancer
Melanoma
Cutaneous benign fibrous histiocytomas
Cylindroma
Pilomatricoma
Spitz tumors
Smooth muscle
Intravenous leiomyomatosis
Soft tissue tumors
Aggressive angiomyxoma
Alveolar rhabdomyosarcoma
Alveolar soft part sarcoma
Angiofibroma
Clear cell sarcoma
Desmoplastic small round cell tumor
Elastofibroma
Embryonal rhabdomyosarcoma
Ewing's tumors/Primitive neurectodermal tumors (PNET)
Extraskeletal myxoid chondrosarcoma
Extraskeletal osteosarcoma
Inflammatory myofibroblastic tumor
Lipoblastoma
Lipoma / benign lipomatous tumors
Lipoma: Chondroid lipoma
Liposarcoma / malignant lipomatous tumors
Liposarcoma: Myxoid liposarcoma
Low grade fibromyxoid sarcoma
Malignant Myoepithelioma
Rhabdomyosarcoma
Soft Tissue Leiomyosarcoma
Soft tissue chondroma
Synovial sarcoma
Hibernomas
Squamous cell Cancer
Stomach Cancer
Testicular Cancer
Germ cell tumors
Spermatocytic seminoma
Thyroid Cancer
Anaplastic (undifferentiated) carcinoma
Medullary carcinoma
Oncocytic tumors
Papillary Carcinoma with inv(7)(q21q34) AKAP9/BRAF
Papillary carcinoma/Adenocarcinoma
Uterine Cancer
Carcinoma of the cervix
Endometrial carcinoma
Leiomyoma
Vulva and Vagina tumors
Vaginal Cancer
Vulval Cancer
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