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{{Under Construction}}
==Primary Author(s)*==
Put your text here (Example: Jane Smith, PhD, Institute of Genomics)
__TOC__
__TOC__
==Cancer Category/Type==
==Cancer Category/Type==
Put your text here
==Cancer Sub-Classification / Subtype==
==Cancer Sub-Classification / Subtype==
Put your text here
==Definition / Description of Disease==
==Definition / Description of Disease==
Put your text here
==Synonyms / Terminology==
==Synonyms / Terminology==
Put your text here
==Epidemiology / Prevalence==
==Epidemiology / Prevalence==
Put your text here
==Clinical Features==
==Clinical Features==
Put your text here
==Sites of Involvement==
==Sites of Involvement==
Put your text here
==Morphologic Features==
==Morphologic Features==
Put your text here
==Immunophenotype==
==Immunophenotype==
Put your text here and/or fill in the table
{| class="wikitable sortable"
{| class="wikitable sortable"
|-
|-
! Finding !! Marker
!Finding!!Marker
|-
|-
|Positive (universal) || CD1
|Positive (universal)||EXAMPLE CD1
|-
|-
|Positive (subset) || CD2
|Positive (subset)||EXAMPLE CD2
|-
|-
|Negative (universal) || CD3
|Negative (universal)||EXAMPLE CD3
|-
|-
|Negative (subset) || CD4
|Negative (subset)||EXAMPLE CD4
|}
|}
==Chromosomal Rearrangements (Gene Fusions)==
==Chromosomal Rearrangements (Gene Fusions)==
Put your text here and/or fill in the table
{| class="wikitable sortable"
{| class="wikitable sortable"
|-
|-
! Chromosomal Rearrangement !! Genes in Fusion (5’ or 3’ Segments) !! Pathogenic Derivative !! Prevalence
!Chromosomal Rearrangement!!Genes in Fusion (5’ or 3’ Segments)!!Pathogenic Derivative!!Prevalence
|-
|-
|t(9;22) || BCR-ABL1 || der(22) || 5%
|EXAMPLE t(9;22)(q34;q11.2)||EXAMPLE 3'ABL1 / 5'BCR||EXAMPLE der(22)||EXAMPLE 5%
|-
|-
|t(8;21) || RUNX1-RUNXT1 || der(8) || 5%
|EXAMPLE t(8;21)(q22;q22)||EXAMPLE 5'RUNX1 / 3'RUNXT1||EXAMPLE der(8)||EXAMPLE 5%
|}
|}
===Additional Description:===
==Characteristic Chromosomal Aberrations / Patterns==
Put your text here
==Genomic Gain/Loss/LOH==
==Genomic Gain/Loss/LOH==
Put your text here and/or fill in the table
{| class="wikitable sortable"
{| class="wikitable sortable"
|-
|-
! Chromosome Number !! Gain/Loss/Amp/LOH !! Region
!Chromosome Number!!Gain/Loss/Amp/LOH!!Region
|-
|-
| 8 || Gain || chr8:0-1000000
|EXAMPLE 8||EXAMPLE Gain||EXAMPLE chr8:0-1000000
|-
|-
|7 || Loss || chr7:0-1000000
|EXAMPLE 7||EXAMPLE Loss||EXAMPLE chr7:0-1000000
|}
|}
===Additional Description:===
==Gene Mutations (SNV/INDEL)==
Put your text here and/or fill in the tables
{| class="wikitable sortable"
{| class="wikitable sortable"
|-
|-
! Gene !! Mutation !! Oncogene/Tumor Suppressor/Other !! Presumed Mechanism (LOF/GOF/Other; Driver/Passenger) !! Prevalence (COSMIC/TCGA/Other)
!Gene!!Mutation!!Oncogene/Tumor Suppressor/Other!!Presumed Mechanism (LOF/GOF/Other; Driver/Passenger)!!Prevalence (COSMIC/TCGA/Other)
|-
|-
| TP53 || R273H || Tumor Suppressor || LOF || 20%
|EXAMPLE TP53||EXAMPLE R273H||EXAMPLE Tumor Suppressor||EXAMPLE LOF||EXAMPLE 20%
|}
|}
===Additional Description:===
===Other Mutations===
{| class="wikitable sortable"
|-
!Type!!Gene/Region/Other
|-
|Concomitant Mutations||EXAMPLE IDH1 R123H
|-
|Secondary Mutations||EXAMPLE Trisomy 7
|-
|Mutually Exclusive||EXAMPLE EGFR Amplification
|}
==Epigenomics (Methylation)==
==Epigenomics (Methylation)==
Put your text here
==Genes and Main Pathways Involved==
==Genes and Main Pathways Involved==
Put your text here
==Diagnostic Testing Methods==
==Diagnostic Testing Methods==
Put your text here
==Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)==
==Clinical Significance (Diagnosis, Prognosis and Therapeutic Implications)==
Diagnosis: Put your text here
Prognosis: Put your text here
Therapeutic: Put your text here
==Familial Forms==
==Familial Forms==
Put your text here
==Other Information==
==Other Information==
Put your text here
==Links==
==Links==
Put your links here (use "Link" icon at top of page)
==References==
==References==
(use "Cite" icon at top of page)
<references />
===EXAMPLE Book===
#Arber DA, et al., (2017). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Arber DA, Hasserjian RP, Le Beau MM, Orazi A, and Siebert R, Editors. IARC Press: Lyon, France, p129-171.
==Notes==
<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page. If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage). Additional global feedback or concerns are also welcome.
=== Reference Example, BOOK ===